Brian Martins
A5075221228- Animal Virus Infections Studies
- interferon and immune responses
- Molecular Biology Techniques and Applications
- Microbial infections and disease research
- Bone health and treatments
- Veterinary Oncology Research
- Gene expression and cancer classification
- Viral Infections and Vectors
- Bat Biology and Ecology Studies
- MicroRNA in disease regulation
- Immunotoxicology and immune responses
- Chemokine receptors and signaling
- Bone Metabolism and Diseases
- Genetic and phenotypic traits in livestock
- Identification and Quantification in Food
- Advanced Biosensing Techniques and Applications
- Wildlife Ecology and Conservation
Arizona State University
2023-2024
Abstract Cancer is pervasive across multicellular species, but what explains the differences in cancer prevalence species? Using 16,049 necropsy records for 292 species spanning three clades of tetrapods (amphibians, sauropsids, and mammals), we found that neoplasia malignancy increases with adult mass (contrary to Peto’s paradox) somatic mutation rate decreases gestation time. The relationship between was only apparent when controlled Evolution susceptibility appears have undergone sudden...
<div>Abstract<p>Cancer is pervasive across multicellular species, but what explains the differences in cancer prevalence species? Using 16,049 necropsy records for 292 species spanning three clades of tetrapods (amphibians, sauropsids, and mammals), we found that neoplasia malignancy increases with adult mass (contrary to Peto’s paradox) somatic mutation rate decreases gestation time. The relationship between was only apparent when controlled Evolution susceptibility appears have...
<p>High resolution cladogram from Figure 6 in the main text with species' names as tip labels</p>
<p>Analysis of our results with the outlier species removed</p>
<p>Analysis our of regression results with various data transformation techniques</p>
<p>All of the PGLS regressions done with exception multivariate analysis. The analysis is included as a separate file S41</p>
<p>Multivariate PGLS regression analysis</p>
Cancer is pervasive across multicellular species, but what explains differences in cancer prevalence species? Using 16,049 necropsy records for 292 species spanning three clades (amphibians, sauropsids and mammals) we found that neoplasia malignancy increases with adult weight (contrary to Petos Paradox) somatic mutation rate, decreases gestation time. Evolution of susceptibility appears have undergone sudden shifts followed by stabilizing selection. Outliers include the common porpoise...
Abstract Cancer is pervasive across multicellular species, but what explains differences in cancer prevalence species? Using 16,049 necropsy records for 292 species spanning three clades (amphibians, sauropsids and mammals) we found that neoplasia malignancy increases with adult weight (contrary to Peto’s Paradox) somatic mutation rate, decreases gestation time. Evolution of susceptibility appears have undergone sudden shifts followed by stabilizing selection. Outliers include the common...