A5039257302- Sinusitis and nasal conditions
- Genetic Neurodegenerative Diseases
- Mitochondrial Function and Pathology
- Head and Neck Surgical Oncology
- Autophagy in Disease and Therapy
- Nasal Surgery and Airway Studies
- Cancer, Stress, Anesthesia, and Immune Response
- Neuroblastoma Research and Treatments
- Oral and Maxillofacial Pathology
- Olfactory and Sensory Function Studies
- Lung Cancer Research Studies
- Neuroendocrine Tumor Research Advances
Second Hospital of Shanxi Medical University
2018-2024
Shanxi Medical University
2018-2024
Macquarie University
2024
Abstract Spinocerebellar ataxia type 3 (SCA3, also known as Machado Joseph disease) is a fatal neurodegenerative disease caused by the expansion of trinucleotide repeat region within ATXN3/MJD gene. Mutation ATXN3 causes formation ataxin‐3 protein aggregates, neurodegeneration, and motor deficits. Here we investigated therapeutic potential mechanistic activity sodium butyrate (SB), salt butyric acid, metabolite naturally produced gut microbiota, on cultured SH‐SY5Y cells transgenic zebrafish...
The latest research findings on bidirectional regulation of neuro-immunity through traditional neural circuits shed new light the theoretical basis role vidian neurectomy (VN). This article aims to provide a comprehensive understanding VN, including history principle neuroimmuno-interaction, applied anatomy VN as well methods transnasal endoscopic surgery. Additionally, we introduce concept nose-brain axis, which was proposed based advancement in area neuro-immune interactions.
Objective:The aim of this study is to explore an improved trans-nasal endoscopic surgical approach for vidian neurectomy. Method:Ninety-one patients with nasal hyperreactive disease were collected, including 49 cases allergic rhinitis and 42 non rhinitis. All sufferers enrolled in the have treated medicine, but symptoms not effectively controlled. Preoperative CT localization canal was performed each candidate. During surgery a"Three-step" followed under guidance accordance operation...
上气道高反应性（upper airway hyperresponsiveness，AHR）疾病主要包括变应性鼻炎、血管运动性鼻炎、局部变应性鼻炎、非变应性鼻炎伴嗜酸细胞增多综合征等，是一类高度异质性疾病，发病率高，发病机制复杂。除了传统的免疫学理论外，还存在神经免疫机制。本文主要介绍神经免疫的基本概念和研究进展；AHR时神经免疫的主要形式，如神经源性炎性反应，2型固有淋巴细胞诱导的Th2样反应等；瞬时受体电位及其在冷热刺激诱发神经源性炎性反应和免疫源性炎性反应中的作用机制；生物钟紊乱及其对外周靶器官生物时相的影响；最后结合翼管神经切断术介绍神经阻断在神经免疫调控中的作用。.
Objective: To investigate the clinical and pathological features, treatments prognosis of laryngeal neuroendocrine carcinoma (LNEC). Methods: We conducted retrospective analysis data 12 patients with LNEC admitted to Department Otorhinolaryngology Head Neck Surgery, Second Hospital Shanxi Medical University from May 2014 December 2021, including 9 males 3 females, aged 50-77 years. There were 4 cases typical carcinoid tumour (highly differentiated), 5 atypical (moderately differentiated)...
Abstract Spinocerebellar ataxia type 3 (SCA3, also known as Machado Joseph disease) is a fatal neurodegenerative disease caused by expansion of the trinucleotide repeat region within ATXN3/MJD gene. Mutation ATXN3 causes formation ataxin-3 protein aggregates, neurodegeneration and motor deficits. Here we investigated therapeutic potential mechanistic activity sodium butyrate (SB), salt butyric acid, metabolite naturally produced gut microbiota, on cultured SH-SY5Y cells transgenic zebrafish...