A5091164309- Attention Deficit Hyperactivity Disorder
- Neurogenetic and Muscular Disorders Research
- Antibiotics Pharmacokinetics and Efficacy
- Congenital Anomalies and Fetal Surgery
- Neurotransmitter Receptor Influence on Behavior
- Pharmacological Effects and Toxicity Studies
- Functional Brain Connectivity Studies
- Epilepsy research and treatment
- Antimicrobial Resistance in Staphylococcus
- Pneumocystis jirovecii pneumonia detection and treatment
- Drug-Induced Adverse Reactions
- Gastrointestinal disorders and treatments
- RNA modifications and cancer
- Pediatric Hepatobiliary Diseases and Treatments
- Congenital heart defects research
- Emergency and Acute Care Studies
- Evacuation and Crowd Dynamics
- Disaster Management and Resilience
- Intestinal Malrotation and Obstruction Disorders
- Congenital Heart Disease Studies
- Metabolism and Genetic Disorders
- Inflammatory mediators and NSAID effects
- Dialysis and Renal Disease Management
- Neural and Behavioral Psychology Studies
- Disaster Response and Management
Ehime University
2016-2024
Ehime University Hospital
2019
Ehime Prefectural Central Hospital
2016
With improved treatments, patients with Duchenne muscular dystrophy (DMD) can survive far beyond adolescence. However, advanced-stage DMD are at risk of developing renal dysfunction. In this study, long-term function outcomes and associated factors in advanced stage were analyzed.Fifty-one classified into three different age groups (<20, 20-29, ≥30 years age), cystatin C (CysC) levels compared among groups.Median serum CysC 0.74 mg/L, 0.63 0.76 mg/L the <20, years, respectively (P = .003)....
We evaluated the efficacy of linezolid treatment in 6 children with health care-associated meningitis or ventriculitis (HCAMV) caused by gram-positive cocci. All were diagnosed and treated at Ehime University Hospital between January 2010 December 2017. Of these, 5 as an empirical therapy. In these patients, vancomycin was initially used but changed to because cerebrospinal fluid (CSF) culture positivity (n = 3) a high minimum inhibitory concentration 2). The most common HCAMV pathogens...
Streptococcus pyogenes (also referred to as group A streptococci, GAS) causes severe invasive diseases such bacteremia, necrotizing fasciitis, pneumonia, osteomyelitis, septic arthritis, and toxic shock syndrome in children. However, there are only a few reports on pleural empyema caused by GAS Here, we report the case of 4-year-old boy who presented with due after influenza virus infection. With intravenous antibiotic administration continuous chest-tube drainage, followed video-assisted...
Stevens-Johnson syndrome (SJS) with respiratory distress can lead to fatal outcomes. However, there are a few reports of drug-induced lung injury diffuse alveolar damage caused by acetaminophen, the most severe type. Here, we describe case acetaminophen-induced SJS in child irreversible lesions.
In addition to genetic factors, environmental factors play a role in the pathogenesis of attention deficit/hyperactivity disorder (ADHD). This study used Lister hooded rats (LHRs) as ADHD model animals evaluate effects factors. Male LHR pups were kept four rearing conditions from postnatal day 23 (4 standard cage; 12 large flat and 4 or an enriched environment [EE]) until 9 weeks age. EE but not cage decreased activity LHRs open field test that was conducted for 7 consecutive days. drop...
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Pediatric sigmoid volvulus is a rare but emergency disease caused by abnormal twisting of the bowel along mesenteric axis [1] [2]. Water immersion colonoscopy has been reported to be effective for because it minimizes colonic distension and improves visibility [3] [4]. Gel-immersion endoscopy new method securing visual field during [5]. The gel better than water removing contaminated fluid improving visibility. Moreover, weight opens colon facilitates passage. We present case pediatric...
Nonocclusive mesenteric ischemia (NOMI) defines acute without occlusion of the arteries. The most common cause NOMI is vasoconstriction or vasospasm a artery. generally affects patients >50 years age, and few cases have been reported in children. A 15-year-old boy with severe neurodevelopmental disability developed sudden-onset fever, abdominal distention, dyspnea. Laboratory radiological findings indicated intestinal obstruction prerenal failure. He transient cardiopulmonary arrest...
The authors declare no conflict of interest.
The indications for surgical intervention epilepsy associated with chromosomal abnormalities remain controversial. We report a 13-year-old girl trisomy 21 and refractory epilepsy. patient developed West syndrome at the age of 5 months. seizures were to multiple antiepileptic drugs, adrenocorticotropic hormone therapy, ketogenic diet. Lennox-Gastaut 7 years. Frequent daily including several sound-induced tonic impeded living her caregivers. For alleviation these seizures, underwent total...
Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disorder. Al-though there was no cure for SMA, newly developed therapeutic drugs (nusinersen, onasemnogene abeparvovec, and risdiplam) have been proven effective the improvement of motor function prevention respiratory insufficiency infants with SMA. Nusinersen introduced in Japan 2017 abeparvovec 2020. We hypothesized that introduction these might influence incidence SMA (more precisely, increase diagnosis rate SMA)...
Stevens–Johnson syndrome (SJS) with respiratory distress can lead to fatal outcomes. However, there are a few reports of drug-induced lung injury diffuse alveolar damage caused by acetaminophen, the most severe type. Here, we describe case acetaminophen-induced SJS in child irreversible lesions.
Although 22q11.2 deletion syndrome (22q11.2DS) is one of the most common chromosomal syndromes, there are only a few previous reports linking recurrent febrile seizures and 22q11.2DS. Here, we present case 12-year-old boy in whom 22q11.2DS was first diagnosed at on-set genetic epilepsy plus. The patient presented with more than 10 since age 8 months. From 11 years, he experienced afebrile generalized tonic-clonic seizures. He for time 12 years. recognition hypocalcemia as well atypical but...
Abstract Genetic factors play a critical role in the pathogenesis of attention deficit/hyperactivity disorder (ADHD), but environmental may also be responsible for ADHD symptoms. In this study, Lister hooded rats (LHRs), which are outbred that exhibit more hyperactive, inattentive, and impulsive behaviors than Wistar rats, were used as model animals. Male LHR pups kept four rearing conditions from postnatal day 23 (4 standard cage; 12 large flat 4 or large, tall cage with an enriched...