A5048741217- Disaster Response and Management
- COVID-19 Clinical Research Studies
- Inflammatory Biomarkers in Disease Prognosis
- Long-Term Effects of COVID-19
- Traumatic Ocular and Foreign Body Injuries
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac Arrest and Resuscitation
- Health and Conflict Studies
- Intestinal Malrotation and Obstruction Disorders
- Respiratory Support and Mechanisms
- Congenital Diaphragmatic Hernia Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Pain Management
- Trauma Management and Diagnosis
- Intestinal and Peritoneal Adhesions
- Pancreatic and Hepatic Oncology Research
- SARS-CoV-2 and COVID-19 Research
- Pancreatitis Pathology and Treatment
- Esophageal and GI Pathology
- Abdominal Surgery and Complications
- Bacillus and Francisella bacterial research
- COVID-19 Impact on Reproduction
- Dermatological and COVID-19 studies
- Airway Management and Intubation Techniques
- Autopsy Techniques and Outcomes
Assuta Medical Center
2020-2025
Ben-Gurion University of the Negev
2021-2025
Rambam Health Care Campus
2006-2017
Technion – Israel Institute of Technology
2004-2013
Tel Aviv University
1996-2005
Tel Aviv Sourasky Medical Center
2001-2005
Meir Medical Center
1998-2005
BackgroundWe assessed outcome of patients with moderate and severe COVID-19 following treatment convalescent plasma (CP) the association IgG levels in transfused CP.MethodsA prospective cohort study. Primary was improvement at day 14 defined as alive, not on mechanical ventilation, moderate, mild, or recovered from COVID-19. Antibody CP units were unknown time treatment. against spike protein S1 subsequently measured by ELISA. Neutralizing antibodies titers determined a subset. Outcome...
To assess the analgesic efficacy of patient-controlled bupivacaine wound instillation, 50 patients undergoing major intraabdominal surgery were enrolled into this prospective, placebo-controlled, double-blinded study. In all cases, a standard general anesthetic was administered. On completion surgery, two multihole 20-gauge epidural catheters tunneled through proximal and distal apices surgical placed above fascia such that tips at margin first second thirds wound, respectively....
Blast injuries are rare, and although blast-induced perforation of the bowel have been described in past, entity a delayed caused by an evolving injury not reported. We report three men injured explosion terrorist bombing open air. They suffered primary blast injuries, which resulted isolated perforations terminal ileum. were operated at different times after event. The resected specimens examined under light microscopy. One patient was immediately, had In other two patients, abdominal...
Coronavirus disease 2019 (Covid-19) is associated with high incidence of venous and arterial thromboembolic events. Currently, there are no markers to guide antithrombotic therapy in Covid-19. Immature platelets represent a population hyper-reactive This prospective study compared consecutive Covid-19 patients (n = 47, median age 56 years) acute myocardial infarction (AMI, n 100, 59 group stable cardiovascular risk factors 64, 68 years). platelet fraction (IPF) immature count (IPC) were...
Bombings and explosion incidents directed against innocent civilians are the primary instrument of global terror. In present review we highlight major observations lessons learned from these events. Five mechanisms blast injury outlined different type that they cause is described. Indeed, consequences terror bombings differ those non-terrorism trauma in severity complexity injury, constitute a new class casualties conventional trauma. The clinical implications bombing, treatment dilemmas...
Coronavirus disease 2019 (COVID-19) is associated with a high incidence of thromboembolic events, both venous and arterial. There are currently no specific clinical or laboratory markers to guide antithrombotic therapy for COVID-19 patients. Immature platelets represent population hyper-reactive arterial thrombotic events. This prospective study compared consecutive severe patients (n = 53, median age 73 years) versus sepsis from another origin 41, 69 years). Total platelet counts, immature...
Objective: Bombing is the primary weapon of global terrorism, and it results in a complicated, multidimensional injury pattern. It induces bodily injuries through well-documented primary, secondary, tertiary, quaternary mechanisms blast. Their effects dictate special medical concern timely implementation diagnostic management strategies. Our objective to report on new clinical observations patients admitted Tel Aviv Medical Center following recent terrorist bombing.Results: The explosion...
Objective: Bombing is the primary weapon of global terrorism, and it results in a complicated, multidimensional injury pattern. It induces bodily injuries through well-documented primary, secondary, tertiary, quaternary mechanisms blast. Their effects dictate special medical concern timely implementation diagnostic management strategies. Our objective to report on clinical observations patients admitted Tel Aviv Medical Center following terrorist bombing. Results: The explosion injured 27...
Once a patient has been diagnosed with severe COVID-19 pneumonia, treatment options have limited effectiveness. Opaganib is an oral under investigation being evaluated for of hospitalized patients pneumonia. A randomized, placebo-controlled, double-blind phase 2/3 trial was conducted in 57 sites worldwide from August 2020 to July 2021. Patients received either opaganib (n = 230; 500 mg twice daily) or matching placebo 233) 14 days. The primary outcome the proportion no longer requiring...
To evaluate the efficacy and safety of a long acting somatostatin analogue in subset patients with refractory rheumatoid arthritis (RA).Ten active, RA, who had failed to respond at least four disease modifying antirheumatic drugs (DMARDs), were treated monthly intramuscular injections 20 mg preparation octreotide (Sandostatin-LAR) for three months. They evaluated every two weeks an open label pilot study. The primary measure clinical response was American College Rheumatology criteria 20%...
Mass casualty incidents (MCI) resulting from terrorist bombings pose special problems and may overwhelm even the most experienced trauma centre. Although role assignments for MCI management control are documented, we would like to share several aspects that have found be crucial of bombing MCI. Twelve topics possible answers were brought up discussed extensively in debriefing sessions our institution. They two main categories: functions key personnel, principles definitions. The first...
Coronavirus disease 2019 (Covid-19) is associated with a high incidence of venous and arterial thromboembolic events. Currently, there are no clinical or laboratory markers that predict thrombotic risk. Circulating immature platelets hyper-reactive platelets, which The aim this study was to assess whether the proportion circulating severity in Covid-19 patients. Patients admitted were prospectively assessed. Immature platelet count (IPC) fraction (IPF) measured at admission additional time...
Objectives: To determine whether placental cell therapy PLacental eXpanded (PLX)-PAD (Pluristem Therapeutics, Haifa, Israel) may be beneficial to treating critically ill patients suffering from acute respiratory distress syndrome due coronavirus disease 2019. Design: Retrospective case report of 2019 treated with March 26, 2020, April 4, follow-up through May 2, 2020. Setting: Four hospitals in Israel (Rambam Health Care Campus, Bnai Zion Medical Center, and Samson Assuta Ashdod University...
Paran, Haim MD, FACS; Mayo, Ami MD; Afanasiev, Alexander Epstein, Tsvi Neufeld, David Kluger, Yoram Shwartz, Ivan MD Author Information
Various metal objects added to explosives increase and diversify the wounding from bombing; especially favoured are spherical missiles for their special injuring characteristics. Our objective was study medical consequences ballistic effects on human tissue of pellets used in terrorist bombings.The clinical forensic data all bodily injured casualties a suicide bombing crowded hotel dining room were analysed retrospectively.Of 250 people at scene, 164 injured, with 91 (55.5%) suffering...
In spite of the availability high-tech devices for wound assessment, plastic surgeons recognize that color and confluence granulation tissue are most important indicators open-wound healing. We developed a simple inexpensive pocket-size scale--the Granulometer--to facilitate finer assessment to standardize documentation This device overcomes limitations set by conditions such as lighting or recent exposure other wounds could distort examiner's perception in question. this study we examined...
ABSTRACT Rationale There are few treatment options for severe COVID-19 pneumonia. Opaganib is an oral under investigation. Objective Evaluate opaganib in hospitalized patients with Methods A randomized, placebo-controlled, double-blind phase 2/3 trial was conducted 60 sites worldwide from August 2020 to July 2021. Patients received either (n=230; 500mg twice daily) or matching placebo (n=233) 14 days. Main Outcome Measurements Primary outcome the proportion of no longer requiring...