- Schizophrenia research and treatment
- Electroconvulsive Therapy Studies
- Attention Deficit Hyperactivity Disorder
- Immunodeficiency and Autoimmune Disorders
- Spacecraft Design and Technology
- Venous Thromboembolism Diagnosis and Management
- Neurological disorders and treatments
- Bipolar Disorder and Treatment
- Cardiac Health and Mental Health
- Multiple Sclerosis Research Studies
- Treatment of Major Depression
- Diet and metabolism studies
- Blood Pressure and Hypertension Studies
- Parkinson's Disease Mechanisms and Treatments
- Autoimmune Neurological Disorders and Treatments
- Lipoproteins and Cardiovascular Health
- Tryptophan and brain disorders
- Atrial Fibrillation Management and Outcomes
- Advanced MIMO Systems Optimization
- Monoclonal and Polyclonal Antibodies Research
- Clinical Laboratory Practices and Quality Control
- Neurological and metabolic disorders
- Particle Detector Development and Performance
- Antenna Design and Optimization
- Antenna Design and Analysis
University of West Bohemia
2016-2024
University Hospital Hradec Králové
2013-2023
Charles University
2012-2023
Czech Technical University in Prague
2022
National Institute of Mental Health
2018
University of Hradec Králové
2010-2012
Antipsychotic treatment has been repeatedly found to be associated with an increased risk for venous thromboembolism in schizophrenia. The extent which the propensity is linked antipsychotic medication alone or psychosis itself unclear. objective of this study was determine whether markers thrombogenesis are psychotic patients who have not yet treated medication. We investigated plasma levels indicating activation coagulation (D-dimers and Factor VIII) platelets (soluble P-selectin,...
The increased susceptibility to infection in the Wiskott-Aldrich syndrome (WAS) has led a number of immunochemical studies, with some- what varied results.Kildeberg (1961) found hyperimmunoglobulinaemia raised level 52A (IgA) and Of 252M (IgM) especially y-globulin where precipitation line was pro- longed indicated presence mobility both ft slow °2.Amiet (1963) reported levels all three immunoglobulins his patients.West, Hong, Holland (1962) described large increase IgA 2 cases suffering...
Encephalitis with antibodies against N-methyl-D-aspartate receptor (NMDA-R) is classified as an autoimmune disorder psychotic symptoms, which are frequently dominant. However, it remains unclear how NMDA-R lead to a condition that mimics psychosis and first-episode schizophrenia. In our work, we investigated the presence of in patients (FEP) comparison healthy volunteers.This study included 50 antipsychotic-naïve FEP (including 21 women) volunteers women). The mean age was 27.4 (±7.4) years...
Taxine alkaloids cause fatal poisoning, in particular due to the compound's toxic effect on cardiovascular apparatus.We describe case of a 39-year-old Caucasian man with common yew intoxication for whom cardiopulmonary resuscitation using all available methods, although delayed and extended, was successful.Extended can be used successfully treat intoxication.
Although some studies have described the pharmacokinetics and pharmacodynamics of donepezil in peripheral compartment, focused on drug transport across blood–brain barrier are still very rare. To our knowledge, fluctuation cerebrospinal fluid concentration after administration has not been literature so far. We recruited 16 patients regularly taking a standard therapeutic dose (10 mg per day). All (Caucasian race) were treated for at least three months with stable 10 day prior to sample...
Abstract The role of the immune system as an integral component inflammatory response in pathophysiology migraine remains unclear. aim this study was to evaluate differences parameters (acquired immunity parameters) patients with episodic (EM) and healthy controls. In EM patients, we aimed determine whether changes found peripheral blood were related severity according standardised MIDAS HIT-6 tests. Forty-nine 50 controls included study. authors compared different lymphocyte obtained by...
Psychiatric disorders and treatment with conventional antipsychotic medications have been associated venous thromboembolism, but only a few data on recent antipsychotics such as olanzapine are available.We describe four subjects treated who developed were hospitalized at the University Hospital in Hradec Kralove during period 2004-2006.We found combination of several clinical laboratory risk factors our patients.A cohort study or case-control studies needed to better elucidate possible role...
Objective: Venous thromboembolism (VTE) is a serious multifactorial disorder. Patients with severe mental illness have higher risk of developing the condition compared to general population. Methods: We observed ten cases VTE in patients who were treated antipsychotic drug olanzapine. The diagnosis was made at University Hospital Hradec Kralove (UH HK) from 2004 2013. objectively determined by imaging techniques (duplex ultrasonography, CT angiography) and laboratory tests (D-dimer). average...
Contemporary beam-forming antenna arrays often use a large number of individual elements, sometimes hundreds or more, to achieve high gain for advanced applications like radar, space communication, and next-gen cellular networks. These are complex costly due the need precise amplitude phase adjustments across elements. The feeding network complexity leads signal losses, reduced efficiency, higher noise. Current research aims simplify arrays, reduce active elements needing frontends,...
Objective. We assessed whether antipsychotic drugs represent a risk factor for venous thromboembolism by comparing the prevalence of use in population patients with versus group individuals treated hypertension. Methods. identified 266 (141 women) diagnosed as having at average age 43.1±11 years who had been hospitalized University Hospital Hradec Králové from 1 January 1996 to 31 December 2004. Two hundred and seventy-four (140 arterial hypertension, an 48.3±8.8 years, represented control...
Conventional solution of the ground station for CubeSat commanding during low Earth orbit mission is based on radio amateur equipment and could be implemented quickly with cost. Such case also our in Pilsen, currently used VZLUSAT-1 daily commanding. However this contains several bottlenecks, as we gained experience after collective launch 31 satellites PSLV-C38 carrier. In paper practical experiences class satellite are described, especially limitations conventional solutions aspects small...