A. L. Guajardo-Aldaco

ORCID: 0009-0006-4116-7554
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Systemic Lupus Erythematosus Research
  • Rheumatoid Arthritis Research and Therapies
  • Liver Disease Diagnosis and Treatment
  • Pregnancy and Medication Impact
  • Systemic Sclerosis and Related Diseases
  • Adolescent and Pediatric Healthcare
  • Cardiovascular Health and Disease Prevention
  • Viral Infections and Immunology Research
  • Cerebrovascular and Carotid Artery Diseases
  • Eosinophilic Esophagitis
  • Cardiovascular Disease and Adiposity
  • Cardiovascular Health and Risk Factors
  • Lipoproteins and Cardiovascular Health
  • Psoriasis: Treatment and Pathogenesis
  • Spondyloarthritis Studies and Treatments
  • Breastfeeding Practices and Influences
  • Ultrasound and Hyperthermia Applications
  • Inflammatory Myopathies and Dermatomyositis
  • Pharmaceutical studies and practices
  • Cardiac Fibrosis and Remodeling
  • Hematological disorders and diagnostics
  • Gout, Hyperuricemia, Uric Acid
  • Inflammatory Biomarkers in Disease Prognosis
  • Signaling Pathways in Disease
  • Drug-Induced Hepatotoxicity and Protection

Universidad Autónoma de Nuevo León
2023-2025

Hospital Universitario Dr José Eleuterio Gonzalez
2023-2025

Abstract Background Patients with rheumatoid arthritis (RA) have a higher cardiovascular risk (CVR) compared to the general population contributing decreased life expectancy. Systematic and periodic assessment of CVR is recommended in all patients RA. The newly developed PREVENTTM calculator was designed estimate absolute disease provides an atherosclerotic heart failure. Purpose This study aimed evaluate sensitivity specificity new algorithm identify CP RA without prior CVD compare these...

10.1093/ehjci/jeae333.410 article EN European Heart Journal - Cardiovascular Imaging 2025-01-01

Abstract Background Liver tests are used to evaluate liver damage due medication and have gained attention for their potential role in assessing cardiovascular risk (CVR) patients with rheumatoid arthritis (RA) psoriatic (PsA). In the general population, studies suggest that serum gamma-glutamyl transpeptidase (GGT) levels correlate endothelial dysfunction left ventricular (LV) alterations, leading a higher of events. contrast, bilirubin (SB), byproduct heme metabolism known its antioxidant...

10.1093/ehjci/jeae333.411 article EN European Heart Journal - Cardiovascular Imaging 2025-01-01

Abstract Background Rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and psoriatic (PsA) are heterogeneous autoimmune diseases with established cardiovascular involvement associated a higher risk of developing heart failure (HF). Studies have shown greater for HF in rheumatologic patients compared to the general population, however, calculated varies among studies. PREVENTTM is first calculator predict HF. Purpose To evaluate performance novel detect subclinical inflammatory...

10.1093/ehjci/jeae333.473 article EN European Heart Journal - Cardiovascular Imaging 2025-01-01

Abstract Background Platelet/lymphocyte ratio (PLR) has recently been described as a predictor for adverse cardiovascular outcomes, such heart failure and coronary artery disease. In systemic lupus erythematosus (SLE), PLR studied marker of disease activity. not evaluated biomarker in SLE. Purpose To compare the prevalence echocardiographic abnormalities between normal high patients with Methods Cross-sectional, retrospective, descriptive study. Women older than 18 years who met ACR/EULAR...

10.1093/ehjci/jeae333.474 article EN European Heart Journal - Cardiovascular Imaging 2025-01-01

<h3>Background:</h3> Breastfeeding (BF) is associated with multiple benefits for infants and their mothers. Different factors influence its practice, such as the level of knowledge, women's attitude toward feeding practices, mother's confidence in BF her child correctly well sociodemographic determinants. A lack information support makes it difficult women autoimmune rheumatic diseases (ARDs) to make well-informed decisions about infant during long-term disease management [1]....

10.1136/annrheumdis-2024-eular.5740 article EN Annals of the Rheumatic Diseases 2024-06-01

<h3>Background:</h3> Women with autoimmune rheumatic diseases (ARDs) have greater risk of adverse obstetric outcomes during pregnancy, such as perinatal losses. Perinatal loss (PL) is defined a from any gestational age or in the neonatal period [1]; it's considered traumatic event that lead to process grieving, involves emotional reactions sadness, disbelief and anger [2]. Grief can become pathological when daily function wellbeing person compromised. Resilience refers individual's ability...

10.1136/annrheumdis-2024-eular.3549 article EN Annals of the Rheumatic Diseases 2024-06-01

<h3>Background:</h3> An increase in left atrial diameter (LAD) and a greater relative wall thickness (RWT) of the ventricle (LV) has been associated with risk suffering cardiovascular disease (CVD). It shown that hyperuricemia can lead to an LAD RWT healthy adults, but its effect patients inflammatory rheumatic not established. <h3>Objectives:</h3> Compare diagnosed without hyperuricemia. <h3>Methods:</h3> A cross-sectional study was carried out, including aged 40 75 years who met...

10.1136/annrheumdis-2024-eular.502 article EN Annals of the Rheumatic Diseases 2024-06-01

<h3>Background:</h3> Rheumatoid arthritis (RA) is a chronic, autoimmune, and inflammatory disease. Cardiovascular (CV) disease in the main cause of death this population due to presence proinflammatory cytokines, contributing development atherosclerosis endothelial damage. CV risk algorithms for general have shown underestimate real RA patients. The American Heart Association published Predicting Risk EVENTs (PREVENT<sup>TM</sup>) algorithm 2023 assess developing atherosclerotic 10 years...

10.1136/annrheumdis-2024-eular.4682 article EN Annals of the Rheumatic Diseases 2024-06-01

<h3>Background:</h3> Rheumatic diseases have a higher risk of heart failure compared to the non-rheumatic population. Several cardiovascular (CVR) algorithms are used predict outcomes, but none them provide among this The predicting disease EVENTs (PREVENT) calculator uniquely estimates atherosclerotic and risks, offering cost-effective approach population health. <h3>Objectives:</h3> To evaluate performance PREVENT in detecting patients with rheumatic diseases. <h3>Methods:</h3> A...

10.1136/annrheumdis-2024-eular.6028 article EN Annals of the Rheumatic Diseases 2024-06-01

<h3>Background:</h3> The atherogenic index of plasma (AIP) is a novel marker to identify cardiovascular disease. Recently, it was reported that AIP related long-term disease risk in women with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). <h3>Objectives:</h3> To evaluate if RA-patients high present higher prevalence carotid plaque comparison patients RA low AIP. <h3>Methods:</h3> A cross-sectional comparative study including aged 40 75 who fulfilled the ACR/EULAR 2010...

10.1136/annrheumdis-2024-eular.264 article EN Annals of the Rheumatic Diseases 2024-06-01

<h3>Background:</h3> Lupus nephritis is one of the main causes mortality along with cardiovascular diseases. Proteinuria a clinical expression lupus and has recently been established as risk factor. <h3>Objectives:</h3> To associate echocardiographic abnormalities in patients systemic erythematosus (SLE) proteinuria. <h3>Methods:</h3> Cross-sectional, observational, comparative study SLE who met classification criteria ACR/EULAR 2019, aged 18 years or older. Patients diagnosis overlapping...

10.1136/annrheumdis-2024-eular.479 article EN Annals of the Rheumatic Diseases 2024-06-01

<h3>Background:</h3> Systemic Lupus Erythematosus (SLE) is a chronic inflammatory disease characterized by multiple organ damage and high cardiovascular mortality rate. Valvular Heart Disease (VHD) known cardiac manifestation of SLE. Involvement the mitral valve most frequently encountered. Valve replacement in SLE patients established as common surgery, with mean 24 months duration. <h3>Objectives:</h3> To compare prevalence heart according to duration their seropositivity....

10.1136/annrheumdis-2024-eular.297 article EN Annals of the Rheumatic Diseases 2024-06-01

<h3>Background:</h3> Sleep disorders are common in patients with Systemic Lupus Erythematosus (SLE). Up to 80% of SLE have poor sleep quality, and the prevalence rate is 55–81%. Patients a higher risk myocardial involvement, which can result ventricular dysfunction. A shorter duration has been identified as factor for cardiovascular diseases increased mortality. Pseudonormal diastolic function pattern compensatory state progressive heart failure, often underdiagnosed undervalued by...

10.1136/annrheumdis-2024-eular.477 article EN Annals of the Rheumatic Diseases 2024-06-01

<h3>Background:</h3> Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease. The existing evidence suggests that serum uric acid (SUA) contributes to the progression of atherosclerosis by disrupting lipid metabolism, inhibiting nitric oxide synthesis in endothelial cells, fostering proliferation vascular smooth muscle and exacerbating inflammation. acid/serum creatinine ratio (SUA/SCr), which represents levels blood with normalized renal function, associated an increased...

10.1136/annrheumdis-2024-eular.554 article EN Annals of the Rheumatic Diseases 2024-06-01

<h3>Background:</h3> Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death in rheumatoid arthritis (RA) patients. Several risk (CVR) algorithms are used RA patients to predict outcomes, underestimating real CVR. <h3>Objectives:</h3> To compare CVR with carotid US findings without clinical ASCVD and identify which calculator best predictor that correlates plaque (CP). <h3>Methods:</h3> A cross-sectional descriptive study included RA-patients aged 30 79 who fulfilled...

10.1136/annrheumdis-2024-eular.5938 article EN Annals of the Rheumatic Diseases 2024-06-01

Dionicio Angel Galarza-Delgado, M.D., Ph.D., Valeria Gonzalez-Gonzalez, Natalia Guajardo-Jauregui, Jesus Alberto Cardenas-de la Garza, Rosa Icela Arvizu-Rivera, Maria Fernanda Elizondo-Benitez, Andrea Lizbeth Guajardo-Aldaco, Jose Ramon Azpiri-Lopez, Iris Jazmin Colunga-Pedraza, Ph.D.. J Rheum Dis -0001;0:. https://doi.org/10.4078/jrd.2024.0093

10.4078/jrd.2024.0093 article ES cc-by-nc Journal of Rheumatic Diseases 2024-10-08

Abstract Background Anti-cyclic citrullinated peptide (anti-CCP) antibodies and rheumatoid factor (RF), markers of Rheumatoid Arthritis (RA) activity, are associated with adverse cardiovascular outcomes, suggesting a potential link between RA cardiac remodeling. Purpose Our study aimed to explore the correlation antibody levels (anti-CCP RF) left ventricular (LV) remodeling in patients without known heart disease. Additionally, it sought identify other disease-related factors that correlate...

10.1093/eurheartj/ehae666.2729 article EN European Heart Journal 2024-10-01
Coming Soon ...