A5063305428- Alzheimer's disease research and treatments
- Dialysis and Renal Disease Management
- Tryptophan and brain disorders
- Chemotherapy-induced organ toxicity mitigation
- Chronic Disease Management Strategies
- Dementia and Cognitive Impairment Research
- Polyomavirus and related diseases
- Stress Responses and Cortisol
- Potassium and Related Disorders
- Health Literacy and Information Accessibility
- Mobile Health and mHealth Applications
- Nerve injury and regeneration
- Health and Well-being Studies
- Nephrotoxicity and Medicinal Plants
- Magnesium in Health and Disease
- Diagnosis and Treatment of Venous Diseases
- Chronic Kidney Disease and Diabetes
- Health Systems, Economic Evaluations, Quality of Life
- Body Contouring and Surgery
- Parathyroid Disorders and Treatments
- Thermoregulation and physiological responses
- Neurogenesis and neuroplasticity mechanisms
- Frailty in Older Adults
Yokohama City Seibu Hospital
2019-2024
St. Marianna University School of Medicine
2019-2024
Juntendo University
2009-2012
Epidemiologic studies have demonstrated that a history of depression increases the risk developing Alzheimer's disease, particularly among individuals with early-onset depression. On other hand, recent suggested higher amyloid-β protein (Aβ)40 to Aβ42 ratio may be associated future onset disease. Our objective was assess whether pathophysiology involve or affect Aβ metabolism.In this extension case-control pilot study, 193 inpatients DSM-IV major depressive disorder (MDD) (mean age = 55.9...
Depression may increase the risk of developing Alzheimer's disease (AD). Recent large cohort studies have also shown that a low plasma amyloid beta (Abeta)-42 level combined with high Abeta40 increases AD, suggesting Abeta42/40 ratio as useful for identifying mild cognitive impairment and AD. Although several examined Abeta levels in peripheral blood elderly individuals depression, results been inconsistent. Furthermore, no described younger depression.Serum Abeta40, Abeta42 Abeta40/42 were...
Hypomagnesemia, a side effect of proton-pump inhibitors (PPIs), can be asymptomatic. The presence hypocalcemia or hypokalemia is indicative hypomagnesemia; however, the concomitant use PPIs and thiazide may mask hypocalcemia. A 79-year-old woman with history chronic heart failure kidney disease developed symptomatic hypomagnesemia. Five weeks earlier, she had thiazide-induced hyponatremia, so been discontinued. Reviewing patient's charts revealed that three discontinued administrations in...
Brain-derived neurotrophic factor (BDNF) may have an important role in the pathophysiology of depression. Previous studies indicate that serum BDNF levels were lower patients with depression and increased after treatment antidepressants. However, results on remitted been inconsistent. The purpose present study was to determine which factors influence alteration state.Serum evaluated 75 inpatients major depressive disorder (MDD) 108 controls. Multiple regression analyses conducted using as...