A5062883959- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Treatment and Management
- Metabolism, Diabetes, and Cancer
- Liver Disease Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- Chronic Kidney Disease and Diabetes
- Health Systems, Economic Evaluations, Quality of Life
- Helicobacter pylori-related gastroenterology studies
- Cancer, Lipids, and Metabolism
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Heart Failure Treatment and Management
- Diabetes Management and Education
- Blood Pressure and Hypertension Studies
- Acute Myocardial Infarction Research
- Pancreatic and Hepatic Oncology Research
- Chronic Disease Management Strategies
- Lipoproteins and Cardiovascular Health
- Cardiac Health and Mental Health
- Lipid metabolism and disorders
- Cardiac Imaging and Diagnostics
- Cardiovascular and exercise physiology
- Dietary Effects on Health
- Cardiovascular Health and Risk Factors
- Pharmacology and Obesity Treatment
- Obesity, Physical Activity, Diet
Jeju National University Hospital
2024-2025
Prince of Wales Hospital
1999-2020
Chinese University of Hong Kong
1998-2015
Asia Diabetes Foundation
2015
Alice Ho Miu Ling Nethersole Hospital
2001-2006
<h3>PURPOSE</h3> We examined the effects of participating in a "train-the-trainer" program and being peer supporter on metabolic cognitive/psychological/behavioral parameters Chinese patients with type 2 diabetes. <h3>METHODS</h3> In response to our invitation, 79 fair glycemic control (HbA<sub>1c</sub> <8%) agreed participate become supporters. Of 59 who completed successfully, 33 be supporters ("agreed trainees") were each assigned support 10 for 1 year, voluntary extension period 3...
To examine and compare gastrointestinal (GI) symptoms in Hong Kong Chinese Type 2 diabetic outpatients non-diabetic control subjects.A total of 149 patients (66 men 83 women, age (mean +/- SD) 46.8+/-11.1 years) newly referred to the diabetes clinic Prince Wales Hospital, were examined. Sixty-five sex-matched subjects recruited from community as controls (22 43 46.5+/-6.6 years, P = 0.820). All interviewed regarding GI over past year, using a questionnaire that covered 14 items. A scoring...
This study aimed to evaluate the long-term clinical outcomes of patients with acute myocardial infarction (AMI) who underwent successful stent implantation and were subsequently treated angiotensin-converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB). Among 13104 enrolled in Korean AMI registry, 2763 elderly aged 70 years older, prescribed either ACEI ARB at discharge, included this study. Propensity score matching (PSM) was performed adjust for baseline confounders....
Abstract Background Ventricular-arterial coupling (VAC) plays a crucial role in the initiation and progression of heart failure patients with coronary artery disease. The influence VAC on left ventricular (LV) function may vary depending LV systolic function. This study investigated relationship between acute myocardial infarction (AMI), stratified by ejection fraction (EF). Methods Echocardiographic indices volumes, function, diastolic were measured using standard techniques. Effective...
Overweight and metabolic syndrome (MES) are emerging in both adult paediatric populations.To study the prevalence of associated risk factors for MES, using National Cholesterol Education Program definition, among Hong Kong Chinese adolescents studying secondary schools.This was a cross-sectional, population-based study. A sample 2115 randomly selected from 14 schools throughout Kong. Data on anthropometric parameters, fasting blood urine samples were collected school setting. Information...
Summary The purpose of this cross‐sectional study was to examine the risk associations between obesity indexes body mass index (BMI) and waist circumference (WC)], cardiovascular factors plasma glucose lipids, blood pressure urinary albumin excretion (UAE)] morbidity conditions (Type 2 diabetes mellitus, hypertension, dyslipidaemia and/or albuminuria) in Hong Kong Chinese. Seven‐hundred two Chinese subjects (18–65 years age, 59.4% whom had at least one condition) were recruited from Prince...
Visceral fat is believed to be important in the pathogenesis of metabolic syndrome and fatty liver. In this study, we examined relationship between mesenteric thickness other sonographic indices adiposity presence liver among subjects with polycystic ovary (PCOS). A total 117 Chinese PCOS were evaluated (mean age, 28.6 ± 6.5 yr; mean body mass index, 24.3 5.3 kg/m2). Anthropometric measurements risk profile, including a standard oral glucose tolerance test, assessed all subjects. All...
Type 2 diabetic patients have increased cancer risk. We developed and validated an all-site risk score in a prospective cohort of 7374 Chinese type free known history at enrolment, using split-half validation. Spline Cox model was used to detect common factors guide linear transformation non-linear factors. After median follow-up period 5.45 years, 365 (4.95%) cancer. Body mass index (BMI; <24.0 or ≥27.6 kg/m2), triglyceride (≥0.81 <1.41 mmol/l), high-density lipoprotein cholesterol (<0.9...
To develop a simple scoring system for identifying Southern Chinese at risk of diabetes.The score was derived from factor matching cohort Type 2 diabetes in Hong Kong (cohort 1, 2448 subjects without history diabetes; age, mean +/- sd 37.2 8.9 years, median 36.0 years; 1649 had factors and 799 were age-matched control the community). Two other cohorts used to validate 2, 3734 with 3, 1513 participants community survey). All 75 g oral glucose tolerance test (OGTT).In 270 (11%) found have on...
Aim: The aim of this study is to investigate the prevalence metabolic syndrome (MES) in type 2 diabetic patients and predictive values World Health Organization (WHO) National Cholesterol Education Programme (NCEP) definitions individual components MES on total cardiovascular mortality. Methods: A prospective analysis a consecutive cohort 5202 Chinese recruited between July 1994 April 2001. Results: was 49.2–58.1% depending use various criteria. There were 189 deaths (men: 100 women: 89)...
Increased plasma glucose concentration is a predictive factor for mortality in both diabetic and non-diabetic subjects. Although glycated haemoglobin (HbA1c) useful index of mean blood concentrations over the preceding 1 to 3 months, there are few data regarding its relationship cardiovascular risk. We have examined between HbA1c risk factors 1280 subjects with normal tolerance. Based on tertiles (tertile 1: n = 427, 262 men 165 women, level: 2.9–4.7 % 3.2–4.2 women; tertile 2: 426, 261...
Background: The renoprotective effect of angiotensin II antagonists has been demonstrated in type 2 diabetic patients with nephropathy but similar data on angiotensin‐converting enzyme (ACE) inhibitors are limited. We examined the efficacy and tolerability fosinopril, an ACE inhibitor dual hepatic renal clearance, 38 moderate impairment (plasma creatinine 130–300 µmol/l) over a 2‐year period. Methods: This was single‐centre, randomized, double‐blinded, placebo‐controlled trial comparing...
Background. The RENAAL Study has confirmed the renoprotective effects of Losartan in type 2 diabetes. In this subgroup analysis from Study, we hypothesized that intensive care received by patients a clinical trial setting also reduced rate decline renal function through optimization all risk factors.
Background: The aim of this study was to investigate whether chronic infections with Helicobacter pylori and hepatitis B virus (HBV) might affect clinical outcomes in Chinese type 2 diabetic patients advanced nephropathy. Methods: A prospective 97 proteinuria renal insufficiency (median serum creatinine 200 µmol/l). Results: During a median follow‐up period years, 34 developed end‐stage disease (ESRD), 28 had cardiovascular endpoints 11 died (seven men four women), 52.7% combined endpoint....
Abstract Aim Recent studies have shown that the risk of developing coronary heart disease in subjects with ‘isolated low high‐density‐lipoprotein cholesterol (HDL‐C)’ (defined as HDL‐C < 0.9 mmol/l and total (TC) 5.2 mmol/l) was similar to those hypercholesterolaemia. We examined prevalence isolated Hong Kong Chinese its relationship insulin resistance triglyceride (TG) level. Methods ( n = 1493) recruited a population‐based survey for cardiovascular factors were examined. Insulin...
Complete left bundle branch block (CLBBB) is a significant cardiac conduction abnormality often associated with dilated cardiomyopathy (DCM). This case report highlights the improvement in CLBBB and symptom relief through reverse remodeling patient diagnosed DCM following an optimized heart failure treatment regimen consisting of angiotensin-converting enzyme inhibitor, beta-blocker, mineralocorticoid receptor antagonist. potential electrical system patients receiving medical therapy.
Optimal medical therapy, including Beta-blockers (BB), inhibitors of the renin-angiotensin system (RAS), and statins, is recommended for patients with acute myocardial infarction (AMI) in absence contraindications. However, optimal duration these medications has not been clearly established clinical studies. This observational study aimed to investigate period during which are associated improved outcomes. Among enrolled Korea Acute Myocardial Infarction Registry-National Institute Health...