- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Mechanical Circulatory Support Devices
- Cardiovascular Disease and Adiposity
- Cardiac Arrest and Resuscitation
- Infective Endocarditis Diagnosis and Management
- Venous Thromboembolism Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Cardiac, Anesthesia and Surgical Outcomes
- Medical Device Sterilization and Disinfection
- Lipoproteins and Cardiovascular Health
- Cerebrovascular and Carotid Artery Diseases
- Aortic Thrombus and Embolism
- Peripheral Artery Disease Management
- Cardiac and Coronary Surgery Techniques
- Cardiovascular Issues in Pregnancy
- Cardiac pacing and defibrillation studies
- Biomedical Ethics and Regulation
- Cardiac Health and Mental Health
- Central Venous Catheters and Hemodialysis
- Atrial Fibrillation Management and Outcomes
- Viral Infections and Immunology Research
MedStar Washington Hospital Center
2010-2025
MedStar Georgetown University Hospital
2025
Georgetown University
2025
Background Coronary microvascular dysfunction (CMD), which mimics symptoms of obstructive coronary artery disease, has significant prognostic implications. While epicardial adipose tissue normally a protective role, increased is associated with inflammation and may contribute to CMD. However, direct correlation remains unclear. We aimed investigate this association. Methods Results The CMDR (Coronary Microvascular Disease Registry) prospective, 2‐center registry that enrolling patients...
ABSTRACT Background Cangrelor is an intravenous P2Y12 receptor antagonist that exerts rapid and potent antiplatelet effects. It associated with a reduction in the indcidence of ischemic events patients acute coronary syndrome (ACS) undergoing percutaneous intervention (PCI). Aims The aim our study was to investigate racial disparities their impact on outcomes among ACS who were treated cangrelor during PCI. Methods We reviewed data PCI at center from 2018 2023 divided between African...
Previous studies using high-risk criteria to select patients for mechanical circulatory support (MCS) during percutaneous coronary intervention (PCI) have not consistently shown a benefit in reducing adverse outcomes. Identifying correlates intra-procedural hemodynamic instability (HI) may improve patient selection MCS. Consecutive, hemodynamically stable undergoing non-emergent PCI between 2018 and 2022 were reviewed. High-risk patients, defined by left ventricular ejection fraction ≤ 35%...
BACKGROUND: Patients with bicuspid aortic stenosis who receive transcatheter valve replacement (TAVR) may require subsequent interventions in their lifetime; however, the feasibility of redo-TAVR this population is uncertain. We aimed to assess patients and develop a predictive virtual planning algorithm. METHODS: studied computed tomography scans received balloon-expandable heart (THV) LRT trial (Low Risk TAVR). Redo-TAVR feasibility, determined by valve-to-coronary valve-to-aorta...
Periprocedural stroke after transcatheter aortic valve implantation (TAVI) remains a significant issue, which is associated with high morbidity, and increasingly important as intervention shifts to younger lower-risk populations. Over the last decade of clinical experience TAVI, incidence periprocedural has stayed largely unchanged, although it prone underreporting due variation in ascertainment methods. The aetiology TAVI patients multifactorial, changing risk profiles, differing study...
Background: Percutaneous coronary intervention (PCI) of complex lesions (i.e., American College Cardiology/American Heart Association class type C) remains challenging and the outcome may be compromised. The use intravascular ultrasound (IVUS) to guide PCI was suggested improve outcome. Methods: A cohort 1,984 patients who underwent C in our center from April 2000 March 2010 identified. Using propensity score matching with clinical angiographic characteristics, we identified 637 IVUS...
Background: Although bivalirudin use in percutaneous coronary intervention (PCI) results less bleeding compared to unfractionated heparin (UFH) use, its safety patients undergoing rotational atherectomy (RA) is unknown. Methods: A cohort of 503 who underwent PCI with RA from 2000 2009 was studied. Patients receiving (n = 322) were those 181) treated UFH ± glycoprotein IIb/IIIa inhibitor (GPI) as anticoagulation. Safety assessed by the frequency major (hematocrit drop ≥15%, intracerebral or...
The no-reflow phenomenon is an often seen complication in patients presenting with acute coronary syndrome (ACS) undergoing percutaneous intervention (PCI). This event associated poor prognosis and poses a therapeutic challenge.This retrospective study cohort was composed of 30 who presented ACS between September 2007 April 2009, developed during subsequent PCI. primary end-point defined as normal Thrombolysis In Myocardial Infarction (TIMI) 3 flow myocardial blush grade (MBG) >or=2 or...
Objectives: This study aimed to evaluate the safety of low‐dose protamine administration facilitate earlier vascular sheath removal. Background: Vascular access complications are most common cause postprocedural morbidity in patients undergoing peripheral endovascular intervention (PEI). Prolonged manual compression and closure devices do not eliminate these complications. Methods: A consecutive series 166 who underwent PEI were retrospectively compared an all‐comers control group 136 did...
Background: Failed percutaneous coronary intervention (PCI) for ST‐elevation myocardial infarction (STEMI) is associated with adverse outcome. With recent improvements in PCI techniques, the incidence and predictors failed primary are unclear. Methods: A clinical database of consecutive patients who underwent or rescue from 1993 to 2011 was used compare successful versus PCI. Clinical follow‐up obtained in‐hospital, at 30 days 1 year. Results: Of 2900 fulfilling our inclusion criteria, 111...
Background: Chronic renal insufficiency (CRI) is associated with an increased incidence of restenosis and stent thrombosis. Drug‐eluting stents (DES), when compared to bare metal (BMS), reduce the in these patients. This study aimed examine whether there are differences clinical outcome after implantation sirolimus‐eluting (SES) versus paclitaxel‐eluting (PES) patients CRI who subjected coronary intervention. Methods: A cohort 570 underwent intervention DES (346 SES 224 PES) were followed...