A5019449403- Renal and related cancers
- Genital Health and Disease
- HIV, Drug Use, Sexual Risk
- Reproductive tract infections research
- Cancer-related gene regulation
- Hepatitis B Virus Studies
- TGF-β signaling in diseases
- Urologic and reproductive health conditions
- Congenital heart defects research
- Cervical Cancer and HPV Research
- Sexuality, Behavior, and Technology
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Reproductive Biology and Fertility
- Environmental Science and Water Management
- Healthcare cost, quality, practices
- Smoking Behavior and Cessation
- Science, Research, and Medicine
- Sex work and related issues
- Growth Hormone and Insulin-like Growth Factors
- Peptidase Inhibition and Analysis
- Parvovirus B19 Infection Studies
- Food Waste Reduction and Sustainability
- Nutrition, Genetics, and Disease
- Consumer Packaging Perceptions and Trends
- Urticaria and Related Conditions
Wageningen University & Research
2023-2024
Public Health Service of Amsterdam
2011-2021
National Institute for Public Health and the Environment
2020
GGD Amsterdam
2011-2013
Hubrecht Institute for Developmental Biology and Stem Cell Research
1999-2000
Radboud University Nijmegen
1996
Rotterdam University of Applied Sciences
1996
We describe isolation and characterization of the bovine ortholog POU5F1 (bPOU5F1) encoding octamer-binding transcription factor-4 (Oct-4). The organization bPOU5F1 is similar to its human murine orthologs, it shares 90.6% 81.7% overall identity at protein level, respectively. Transient transfection luciferase reporter constructs in P19 embryonal carcinoma cells demonstrated that has a functional promoter contains two enhancer elements, which one repressed by retinoic acid. was mapped major...
A key reason for the occurrence of household food waste is poor meal planning, which partly due to inappropriate discrete package sizes at supply level and lack accounting unused consumer level. Diet modeling has proven be effective solving planning problems. As far as we know, have not been incorporated in a dietary model before. The mathematical programming based formulated this article proposes plans shopping lists by selecting combinations recipes on available retail such that waste,...
Testicular germ cell tumors are the most common form of cancer in young adult males. They result from a derangement primordial cells, and they grow out noninvasive carcinoma-in-situ precursor. Since carcinoma situ can readily be cured by low-dose irradiation, there is great incentive for non- or minimally invasive methods detection situ. We have recently shown that human Tera-2 embryonal obtained nonseminomatous testicular tumor, show alternative splicing promoter use platelet-derived growth...
Signaling by the transforming growth factor (TGF)-beta superfamily is important during kidney development. Here, we describe spatial and temporal expression patterns of Smads, transcription factors that translate TGF- signals into gene expression. RT-PCR data in situ hybridization analysis showed receptor-regulated (R) Smads (Smad1, -2, -3, -5, -8), common partner Smad (Smad4), inhibitory (I) (Smad6 -7) were all expressed mouse development from embryonic day 12 until end nephrogenesis at...
TSC-22 is a highly conserved member of novel family transcription factors, that direct target transforming growth factor-β (TGF-β) in osteoblastic cells. We have investigated the expression detail during mouse development using situ hybridization. detected strong embryo proper first at embryonic day 8.5 (E8.5), primitive heart, intermediate mesoderm and neural tube. The dynamics distribution tube was particularly striking, with ubiquitous rostrally restriction to tissue nearer floor plate...
Human papillomavirus (HPV) vaccination programs achieve substantial population-level impact, with effects extending beyond protection of vaccinated individuals. We assessed trends in HPV prevalence up to 8 years postvaccination among men and women the Netherlands, where bivalent vaccination, targeting types 16/18, has been offered (pre)adolescent girls since 2009 moderate coverage.We used data from PASSYON study, a survey initiated (prevaccination) repeated biennially 16- 24-year-old...
Abstract Objective: To develop a healthy diet for Ethiopian women closely resembling their current and taking fasting periods into account while tracking the cost difference. Design: Linear goal programming models were built three scenarios (non-fasting, continuous intermittent fasting). Each model minimised function of deviations from nutrient reference values eleven nutrients (protein, Ca, Fe, Zn, folate, vitamins A, B 1 , 2 3 6 12 ). The energy intake in optimised diets could only deviate...
Introduction HSV type specific antibodies (IgG1 and IgG2) are produced persist after HSV-1 –2 infections. Therefore, IgG2 serologic tests used as an indicator for genital herpes history (e.g. in pregnant women), to counsel partners of patients, a proxy marker high-risk sexual behaviour. We tested this paradigm by retrospectively measuring IgG1 or sequential serum samples from visitors with symptomatic PCR proven recurring episodes. Methods selected individuals two episodes HSV-2 herpes,...
Background Previous studies have shown that recreational drug use is associated with high-risk sexual behaviour and STI. Little known about the relationship between of specific drugs during sex, risk for any STI (chlamydia (CT), gonorrhoea (NG) and/or syphilis) or three separately in heterosexual men, men having sex (MSM) women. We assessed prevalence assocations Methods Attendees clinic Public Health Service Amsterdam were interviewed waves a bi-annual anonymous survey (2008–2009) preceding...
<h3>Introduction</h3> A PEP indication is an ideal opportunity for safe sex promotion and STI screening. Since 2010 the outpatient clinic in Amsterdam, Netherlands, offers to HIV negative men who have with (MSM) had unprotected receptive anal intercourse within last 72 hours. If screening performed at moment of request, early incubating chlamydia gonorrhoea infections acquired during unsafe act, are possibly missed. We aimed determine if should be repeated MSM 2 weeks after a indication....
<h3>Background</h3> The objective of this study was to provide insight into the motives drug use during work among male sex workers (MSW) and transgender women (TSW) its possible effect on sexual behaviour that may increase chance STIs and/or HIV acquisition. <h3>Methods</h3> From March June 2018, we conducted semi-structured in-depth interviews MSW TSW visiting Prostitution Health Center in Amsterdam. Transcribed were analysed by two researchers with an open-coding process, after which...
Background Community Acquired Methicillin Resistant Staphylococcus aureus (CA-MRSA) has been found more often among men who have sex with (MSM) in some studies (USA). This study assesses the prevalence and sexual risk factors for CA-MRSA methicillin susceptible (MSSA) colonisation infection MSM Amsterdam, Netherlands. Methods attending sexually transmitted infections outpatient clinic Amsterdam were invited to participate this divided two groups: (1) clinical signs of a skin/soft tissue...
<h3>Introduction</h3> Mycoplasma genitalium (MG) is associated with urethritis in men. Treatment of azithromycin expected to become less effective clients infected MG due an increase macrolide resistance-associated mutations (MRAM) MG. Therefore, we examined clinical improvement symptoms men receiving empirical treatment for urethritis, and correlated the outcome Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT), MRAM status. <h3>Methods</h3> At STI clinic Amsterdam, Netherlands,...