A5019364471- Radical Photochemical Reactions
- Synthesis and Catalytic Reactions
- Sulfur-Based Synthesis Techniques
- Antimicrobial agents and applications
- Antimicrobial Peptides and Activities
- Synthesis of heterocyclic compounds
- Fluorine in Organic Chemistry
- Synthesis of Organic Compounds
- Microbial Natural Products and Biosynthesis
- Multicomponent Synthesis of Heterocycles
- Chemical Synthesis and Reactions
- Advanced Decision-Making Techniques
- High voltage insulation and dielectric phenomena
- Power Transformer Diagnostics and Insulation
- Catalytic C–H Functionalization Methods
- Power Systems and Technologies
- Energy Load and Power Forecasting
- Advanced Computational Techniques and Applications
Shanghai Institute of Materia Medica
2024
Chinese Academy of Sciences
2024
Shanghai University
2024
Sulfonamides are important structures in pharmaceuticals, agrochemicals, and organocatalysts, yet the rapid benign synthesis of these compounds is still a great challenge. Herein we report photoinduced method for synthesizing sulfonamides from (hetero)aryl carboxylic acid oxime esters. This reaction proceeds via one-pot cascade radical–radical cross-coupling by energy-transfer-mediated photocatalysis. A wide substrate scope including substrates late-stage modification pharmaceutical...
A concise and efficient protocol for constructing a chromone fused thiazole scaffold via copper-promoted cascade reaction was developed. Representative compound c12 showed good anti-inflammatory activity.
UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase (TarO) has been found to simultaneously contribute β-lactam resistance and virulence of Methicillin-resistant Staphylococcus aureus (MRSA). However, optimization hit compounds targeting TarO hindered due their high lipophilicity the poor correlation between enzyme activity inhibition sensitization. In this study, 31 analogues Tarocin A were designed, synthesized evaluated by a luminescence-based reporter...
As an important equipment in the power system, operating state of transformers is related to safe operation entire system. It great importance determine transformer and take countermeasures advance. Dissolved gas analysis (DGA) one most common methods for evaluation oil-immersed transformer. Therefore, a time series forecasting model based on Seasonal Autoregressive Integrated Moving Average (SARIMA) presented forecast dissolved concentration oil this paper. Firstly, influence period...
Herein we report a metal-free photocatalytic method for amination and heteroarylation of gem -difluoroalkenes.
Sulfonamides, especially primary aryl sulfonamides are very important scaffolds not only because of the wide applications as pharmacophores in drugs, but also derivatization for other and different sulfur-containing...
Abstract In the past, development of transformer maintenance strategies mostly used information data from a single source, and final strategy was too general, unable to intelligently automatically achieve effective guidance for equipment operation maintenance. Based on existing case sets, this article studies representation, feature attributes weights, decision algorithm based case-based reasoning. Firstly, structural similarity between target problem source is analyzed, then two finally,...