A5012947720- Parasites and Host Interactions
- Helminth infection and control
- Pharmaceutical Quality and Counterfeiting
- Pharmaceutical Economics and Policy
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 and COVID-19 Research
- Parasite Biology and Host Interactions
- Global Maternal and Child Health
- Biosimilars and Bioanalytical Methods
- Diverse Scientific Research Studies
- Child Nutrition and Water Access
- Pharmacovigilance and Adverse Drug Reactions
- Tuberculosis Research and Epidemiology
- Viral Infections and Outbreaks Research
- Antibiotic Use and Resistance
- Intellectual Property and Patents
- Parasitic infections in humans and animals
Rwanda Development Board
2020-2024
Rwanda Biomedical Center
2022
Local, national, and international health agencies have advocated multi-pronged public strategies to limit infections prevent deaths. The availability of safe effective vaccines is critical in the control a pandemic. Several adverse events been reported globally following reception different vaccines, with limited or no data from Africa. This cross-sectional epidemiological study investigated COVID-19 vaccination Africans April-June, 2021 using structured online questionnaire. Out 1200...
Preventive chemotherapy (PC) is a WHO-recommended core intervention measures to eliminate Soil-Transmitted Helminths (STH) as public health problem by 2020, defined reduction in prevalence <1% of moderate or high-intensity infection. We conducted cross-sectional study investigate the prevalence, intensity, and correlates STH after decade PC Rwanda. A total 4998 school children (5–15 years old) from four districts along Lake Kivu western province were screened for using Kato-Katz. The...
Access to quality medicines is a global initiative ensure universal health coverage. However, the limited capacity of National Medicines Regulatory Authorities (NMRAs) prevent and detect supply poor-quality led predominance sub-standard falsified (SF) in chains many countries. Therefore, this study was designed assess young NMRA with Rwanda as case study.This aimed FDA, NMRA, identify gaps existing opportunities for improving regulatory ensuring medicines.This used descriptive...
School-based preventive chemotherapy (Deworming) with praziquantel and albendazole to control eliminate schistosomiasis soil-transmitted helminths as public health problems is recommended by the World Health Organization (WHO). Safety monitoring during mass drug administration (MDA) imperative but data from sub-Saharan Africa are scarce. The aim of this active safety surveillance study was identify incidence, type, severity, risk factors for adverse events (AEs) following albendazole....
Mass drug administration (MDA) of single-dose albendazole to all at-risk populations as preventive chemotherapy (deworming) is recommended by WHO halt transmission soil-transmitted helminth (STH) in endemic countries. We assessed the effectiveness against STH infection western province Rwanda, where prevalence remains high despite implementation for over a decade. Two weeks before scheduled MDA, 4998 school children (5-15 years old) were screened infections (Ascaris lumbricoides, Trichuris...
Abstract School-based mass drug administration (MDA) of Praziquantel (PZQ) is the global intervention strategy for elimination schistosomiasis. Genetic variations in metabolizing enzymes and transporter proteins influences exposure treatment outcomes, but data on PZQ pharmacokinetics safety outcomes are scarce. We investigated effect pharmacogenetics plasma concentrations among 462 Rwandan schoolchildren who received single dose albendazole MDA. Genotyping common functional variant alleles...
Preventive chemotherapy with single-dose praziquantel is the WHO-recommended intervention strategy to eliminate schistosomiasis as a public health problem in endemic countries. Surveillance of drugs used mass drug administration (MDA) programs recommended evaluate its effectiveness reducing transmissions. After decade-long implementation school-based MDA program Rwanda, we conducted efficacy surveillance against S. mansoni infection. Two weeks before MDA, stool examinations were performed...
Background : The death toll and economic disaster caused by SARS-CoV-2/ COVID-19 is still on the rise globally in Africa with a case fatality ratio (CFR), 2.58 from 220,958 deaths out of 8,556,890 cases recorded across continent as 14th November 2021. Local, national international health agencies have advocated multi-pronged public strategies to limit infections prevent deaths. availability safe effective vaccine critical control pandemic. Several adverse events been reported for different...
Abstract Background A drug recall is an act of removing products from the market and/or returning them to manufacturer for disposal or correction when they violate safety laws. Action can be initiated by manufacturing company order a regulatory body. This study aimed assess characteristics Rwanda FDA and determine association between classes characteristics. Methodology was retrospective descriptive cross-sectional study. Data about recalled drugs were collected official website in section...
Continuous professional development among stakeholders involved in drug safety monitoring and surveillance is imperative strengthening pharmacovigilance (PV) systems. The "Pharmacovigilance infrastructure post-marketing system capacity building for regional medicine regulatory harmonization East Africa" (PROFORMA) project aims to enhance the national PV infrastructure, systems clinical trial capabilities Ethiopia, Tanzania, Kenya Rwanda. To achieve this, training, including short-term...