A5071478637- Cancer, Lipids, and Metabolism
- Cancer Cells and Metastasis
- Metabolomics and Mass Spectrometry Studies
- Cancer, Hypoxia, and Metabolism
- Phytochemicals and Antioxidant Activities
- Liver Disease Diagnosis and Treatment
- Marine Sponges and Natural Products
- Plant-Derived Bioactive Compounds
- RNA and protein synthesis mechanisms
- Biochemical Analysis and Sensing Techniques
- Mechanisms of cancer metastasis
- Seaweed-derived Bioactive Compounds
- Cancer-related Molecular Pathways
- RNA Research and Splicing
- Cancer Treatment and Pharmacology
- RNA modifications and cancer
- MicroRNA in disease regulation
- Eicosanoids and Hypertension Pharmacology
- Antioxidant Activity and Oxidative Stress
- Alcohol Consumption and Health Effects
- Algal biology and biofuel production
- Tannin, Tannase and Anticancer Activities
Jeju National University
2022-2024
Melosira nummuloides is a microalga with nutritionally favorable polyunsaturated fatty acid profile. In the present study, M. ethanol extract (MNE) was administered to chronic-binge alcohol-fed mice and alcohol-treated HepG2 cells, its hepatoprotective effects underlying mechanisms were investigated. MNE administration reduced triglyceride (TG), total cholesterol (T-CHO), liver injury markers, including aspartate transaminase (AST) alanine (ALT), in serum of mice. However, increased levels...
Oleic acid, found in a variety of food sources, is beneficial to health. However, studies on its anticancer effects cancer stem cells resistant conventional treatments and the mechanisms underlying such are scarce. Here, we evaluated oleic acid against breast with stemness characteristics. inhibited proliferation stem-like more significantly than that their respective parental cells, reduced expression cell markers migration invasion propensity. It also repressed phosphorylation FAK, AKT,...
Bananas, one of the most widely consumed fruits worldwide, are a rich source valuable phytochemicals. In this study, antioxidant and anticancer potential banana flesh was investigated. Of four kinds extracts, hexane extract (HE) had highest total polyphenol content (2.54 ± 0.60 mg GAE/g) flavonoid (1.69 0.34 RE/g), followed by chloroform fraction, ethanol extract, fraction. HE found to exert strong radical scavenging activity on 2,2-diphenyl-1-picrylhydrazyl (DPPH•)...
Abstract Melosira nummuloides is a marine diatom with potential use as food, fuel, and dietary supplement. However, the efficacy of its extraction drying techniques have not been explored. Here, M. powders were prepared by two methods—hot-air (HAD) freeze-drying (FD)—and extracted hot water, ethanol, methanol, chloroform:methanol (CM) at ratio 2:1 v/v. The antioxidant anti-inflammatory activity each extract was investigated. CM had greatest 2,2-diphenyl-1-picrylhydrazyl...
Abstract Introduction Lung cancer is one of the most malignant cancers and leading cause cancer-related deaths worldwide, while acquired chemoresistance would represent a major problem in treatment non-small cell lung (NSCLC) because reduced treatment-effect increased rates recurrence. Methods Real-time PCR Western blotting were employed for investigating mRNA protein expression glutathione peroxidase (GPX) family multidrug resistance 1 (MRP1) A549 A549/CR cells. We also gas chromatography...