A5018454646- Antifungal resistance and susceptibility
- Gut microbiota and health
- Antibiotic Resistance in Bacteria
- Salmonella and Campylobacter epidemiology
- Pneumocystis jirovecii pneumonia detection and treatment
- Sex and Gender in Healthcare
- Fungal Infections and Studies
- Insect symbiosis and bacterial influences
- Vibrio bacteria research studies
- Microbial Natural Products and Biosynthesis
- HIV/AIDS oral health manifestations
- Alkaloids: synthesis and pharmacology
- Diagnosis and treatment of tuberculosis
- Antibiotic Use and Resistance
- Tuberculosis Research and Epidemiology
- Health and Medical Research Impacts
Mbarara University of Science and Technology
2023-2025
This study investigated the prevalence, antimicrobial resistance, and extended-spectrum β-lactamase (ESBL) production in Escherichia coli Salmonella isolated from broiler farms Wakiso district, Uganda. A cross-sectional design was employed between August September 2021. total of 216 were selected using simple random sampling, pooled samples fresh fecal droppings cloacal swabs collected. Microbiological isolation identification conducted on selective media, followed by phenotypic genotypic...
Globally, 10.8 million people were diagnosed with tuberculosis during 2023 causing approximately 1.3 deaths. This study aimed to assess the prevalence and characterization of pyrazinamide resistance by detecting pncA gene among newly Mycobacterium patients attending Bombo General Military Hospital, Central Uganda. Cross-sectional looking at TB in Hospital. The sputum samples confirmed positive using GeneXpert PCR technology, DNA extraction CTAB method, amplification, finally gel...
Background Antimicrobial resistance (AMR) and multidrug (MDR) are escalating global health threats, particularly in low- middle-income countries (LMICs). Understanding gender-specific patterns is essential for inclusive antimicrobial stewardship gender-targeted interventions. Objective To investigate trends AMR MDR among clinical bacterial isolates collected from Mbarara Regional Referral Hospital, Uganda, between a 10-year period (2014–2024). Methods A total of 4,170 non-duplicate subjected...
Background Extended-spectrum β-lactamase (ESBL) producing bacteria pose a global challenge because of resistance developing against wide range antimicrobial agents that complicate available treatment options. Thus, identifying the prevalent bacterial species ESBL enzymes and understanding how they are susceptible to antibiotics is necessary internationally inform effective guidelines. Objective To determine prevalence molecular characterization causing Urinary Tract Infections (UTIs) in...
Background: Despite the increased frequency of oropharyngeal candidiasis among people living with human immunodeficiency virus (HIV), its management is no longer effective due to empirical treatment and emergence antifungal resistance (AFR). This study sought investigate prevalence assess susceptibility profile Candida species isolated from virus. Additionally, we evaluated correlation between CD4 T cell as well viral load counts. Methods: A descriptive cross-sectional was carried out April...
Fungal-bacterial cocolonization and coinfections pose an emerging challenge among patients suspected of having pulmonary tuberculosis (PTB); however, the underlying pathogenic mechanisms microbiome interactions are poorly understood. Understanding how environmental microbes, such as fungi bacteria, coevolve develop traits to evade host immune responses resist treatment is critical controlling opportunistic fungal coinfections. In this project, we propose study coexistence bacterial microbial...
<title>Abstract</title> <bold>Background</bold>: Fungal-bacterial co-colonization and co-infections are emerging among tuberculosis (TB) suspected patients, yet the underlying mechanisms that enable arise from their interactions poorly understood. Understanding how environmental microbes such as fungi bacteria co-evolve develop traits to evade host immune responses resist treatment is critical controlling opportunistic co-infections. We therefore, hypothesize cross-kingdom synergistic...
ABSTRACT Background The emergence and re- of zoonotic bacterial infections the upsurge reflected in current trends antimicrobial-resistant bacteria is a major global concern. Salmonella spp Escherichia coli (E. coli) are two most important food-borne pathogens public health interest incriminated poultry products worldwide hence necessitating constant monitoring microbial food safety measures. purpose this study was to determine prevalence, associated factors antimicrobial susceptibility...
Fungal-bacterial co-colonization and co-infections are emerging among TB-suspected patients, yet the underlying mechanisms that enable arise from their interactions poorly understood. Understanding how environmental microbes such as fungi bacteria co-evolve develop traits to evade host immune responses resist treatment is critical controlling opportunistic co-infections. Our previous work has demonstrated fungal-bacterial can have dramatic impacts on fungal pathogenesis drug resistance....
<sec> <title>BACKGROUND</title> Fungal-bacterial cocolonization and coinfections pose an emerging challenge among patients suspected of having pulmonary tuberculosis (PTB); however, the underlying pathogenic mechanisms microbiome interactions are poorly understood. Understanding how environmental microbes, such as fungi bacteria, coevolve develop traits to evade host immune responses resist treatment is critical controlling opportunistic fungal coinfections. In this project, we propose study...