Nikola Mladenović

ORCID: 0009-0007-1366-5318
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About
Contact & Profiles
Research Areas
  • Regional Development and Management Studies
  • Soil and Land Suitability Analysis
  • Alcohol Consumption and Health Effects
  • Diet, Metabolism, and Disease
  • Liver Disease Diagnosis and Treatment
  • Cannabis and Cannabinoid Research
  • Aortic Disease and Treatment Approaches
  • Cardiovascular Disease and Adiposity
  • Selenium in Biological Systems
  • Polyamine Metabolism and Applications
  • Vascular anomalies and interventions
  • Central Venous Catheters and Hemodialysis
  • Peptidase Inhibition and Analysis
  • Hip and Femur Fractures
  • Galectins and Cancer Biology
  • Anesthesia and Neurotoxicity Research
  • Obstructive Sleep Apnea Research
  • Atrial Fibrillation Management and Outcomes
  • Remote Sensing and Land Use
  • Anesthesia and Sedative Agents
  • Advanced Nanomaterials in Catalysis
  • Adipose Tissue and Metabolism
  • Curcumin's Biomedical Applications
  • Cardiac Structural Anomalies and Repair
  • Intensive Care Unit Cognitive Disorders

Institute for Cardiovascular Diseases of Vojvodina
2018-2024

University of Novi Sad
2019-2024

University of Nis
2021

Institut za kardiovaskularne bolesti Dedinje
2019-2021

Klinički centar Niš
2016-2021

Background and Objectives: Coronary artery bypass graft (CABG) surgery is the most common cardiac surgery. One of main causes postoperative complications increased mortality after CABG inflammatory response. The aim this study was to investigate whether continuous intraoperative dexmedetomidine can reduce increase IL-6 other markers Materials Methods: registered with ClinicalTrials.gov, NCT06378827, accessed on 23 April 2024. This prospective experimental conducted from December 2024...

10.3390/medicina61050787 article EN cc-by Medicina 2025-04-24

The aim of our study was to compare the clinical effects sedation with dexmedetomidine vs. propofol in patients undergoing cardiac surgery and analyze their on duration mechanical ventilation (MV), length stay intensive care unit (ICU), total hospital stay.The included 120 who were randomized a 1:1 ratio into two groups 60 patients. first group sedated continuous doses 0.2-0.7 mcg/kg/h. second 1-2 mg/kg/h.Patients required 2.2 hours less time MV (p<0.001). There positive correlation between...

10.26355/eurrev_202308_33418 article EN PubMed 2023-08-01

Rat bile duct ligation (BDL) represents a useful method that mimics obstructive extrahepatic cholestasis, which is known to be frequent disorder in humans. Polyamines (putrescine, spermidine, and spermine) are one of the key molecules regulating cell proliferation differentiation. This work aimed evaluate potential beneficial properties putrescine rat BDL model by studying several biochemical parameters reflecting liver function polyamine metabolism. Rats were subjected injected with (150...

10.1139/cjpp-2018-0332 article EN Canadian Journal of Physiology and Pharmacology 2018-09-07

Postoperative atrial fibrillation is a frequent complication after coronary artery bypass grafting and associated with increased mortality. The effects of various drugs on the occurrence postoperative have been studied, but no one has looked into effect silymarin fibrillation.

10.21470/1678-9741-2023-0422 article EN PubMed 2024-11-28

Background: Post-operative atrial fibrillation (POAF) is a frequent complication after cardiac surgery. It associated with prolonged hospital stay, increased morbidity, mortality rate and economic costs. The aim of the study was to determine association between values Galectin3 N-terminal pro-B-type natriuretic peptide (NTproBNP) POAF Methods: A prospective enrolled patients aged 18-85 years old admitted due elective coronary artery bypass graft surgery (CABG) or CABG + aortic valve...

10.5937/jomb0-47001 article EN cc-by Journal of Medical Biochemistry 2023-12-13

Background/Aim. Alcohol is the most common cause of fatty liver. metabolism takes place in liver by alcohol dehydrogenase, to toxic acetaldehyde, with acids accumulation as a consequence. By daily intake amount greater than 80 g/day for men and 20 g women, there risk developing alcoholic (AFLD). The aim this study was determine profile atherogenic factors plasma patients AFLD compared non-alcoholic (NAFLD) its diagnostic significance. Methods. included 74 who consumed beverages large...

10.2298/vsp150619170m article EN cc-by-sa Vojnosanitetski pregled 2016-07-11

Medical staff that makes the initial contact with patient aortic dissection has a goal to rise suspicion and recognize dissection, as well safely transport health center capable of providing definite treatment. First step in prehospital management is oxygen support via breathing mask prevent organ damage. It important monitor all vital functions during transport, including heart rhythm diuresis, order have continuous insight into patient's current state case deterioration react...

10.5937/scriptamed50-21282 article EN cc-by SCRIPTA MEDICA 2019-01-01

Obstructive sleep apnea (OSA) is a serious disorder of breathing during characterized by complete or partial interruption for 10 seconds and longer.In this prospective longitudinal clinical study in obese patients with diabetes mellitus type II which determined polysomnography heavy degree OSA accompanied the application positive pressure course three months evaluated its impact on value glycated hemoglobin HbA1c as an indicator long-term glycoregulation.A quarterly monitoring included 98...

10.5633/amm.2019.0207 article EN cc-by Acta Medica Medianae 2019-06-15

The inferior vena cava (IVC) collects blood from the abdomen and lower extremities, climbs retroperitoneum enters into right atrium of heart.Obstruction IVC can be caused by venous thrombosis, a neoplasm that exerts external pressure on vein or infiltrates pregnancy.Obstruction causes edema dilatation veins part which serve as collaterals.In diagnosis these disorders, it is necessary to perform detailed laboratory tests, ultrasound abdomen, computerized tomography, finally cavography.In this...

10.5633/amm.2021.0309 article EN cc-by Acta Medica Medianae 2021-09-15
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