A5026464567- Biotin and Related Studies
- Eicosanoids and Hypertension Pharmacology
- Traumatic Brain Injury and Neurovascular Disturbances
- Molecular Junctions and Nanostructures
- Vanadium and Halogenation Chemistry
- Click Chemistry and Applications
- Radiation Effects and Dosimetry
- Catalysis and Hydrodesulfurization Studies
- Neuroscience and Neuropharmacology Research
- Metabolism and Genetic Disorders
- Biochemical effects in animals
- Amino Acid Enzymes and Metabolism
- Microbial Metabolic Engineering and Bioproduction
- Electrochemical sensors and biosensors
- Microbial metabolism and enzyme function
- Diet and metabolism studies
- Enzyme Catalysis and Immobilization
- Blood properties and coagulation
- Phytochemicals and Antioxidant Activities
- Anesthesia and Neurotoxicity Research
- Advanced MRI Techniques and Applications
- Selenium in Biological Systems
- Marine and Coastal Research
- Cerebrospinal fluid and hydrocephalus
- Amoebic Infections and Treatments
University of Fukui
2011-2024
Kyoto University
1972-2005
Tokai University
1993-2002
Tottori University
1993-2002
Kagawa University
1998
Centre National de la Recherche Scientifique
1995
Kindai University
1993
Université Paris Cité
1992
Keio University
1989-1990
Bromoperoxidase was purified from the crude extract of Corallina pilulifera to be homogeneous upon polyacrylamide disc gel and sodium dodecyl sulfatepolyacrylamide electrophoreses according procedures previously reported (Itoh, N., Izumi, Y., Yamada, H. (1985) Biochem.Biophys.Res.Commun.13 1, 428-435).The enzyme had a molecular weight approximately 790,000 composed 12 subunits identical weights (Mr 64,000).Hexagonal shapes were observed by electron microscopy.The isoelectric point 3.0,...
Several 2,3-unsaturated carboxylic acids, such as trans-cinnamic acid and its derivatives, were found to be halogenated by chloroperoxidase of Caldariomyces fumago in the presence hydrogen peroxide either GIor Br-.Cinnamic acid, 4-hydroxycinnamic 4-methoxycinnamic 3,4-dimethoxycinnamic suitable substrates chloroperoxidase, converted 2-halo-3-hydroxycarboxylic 2,3-dihydroxycarboxylic decarboxylated halohydrin, or halocompound.However, 4-nitrocinnamic 4-chlorocinnamic having...
The properties of the nonheme iron bromoperoxidase from Corallina pilulifera were studied. enzyme lost its activity when reduced with formamidine-sulfinic acid and recovered it oxidized by air. Incubation ferric or ferrous ion-chelating agents indicated that was ferric. Analyses circular dichroism proton NMR spectra suggested ion tightly bound to cysteine, histidine, tyrosine residues enzyme. catalyzed Br--dependent catalase reactions yield 1 mol O2 2 H2O2. No evolution observed bromination...
To evaluate the effects of infusion with hyperosmolar solutions, mannitol and glycerol on recovery cerebral energy metabolism during ischemia reperfusion in gerbil brain.Sequential changes following 90-min up to 8 h after were measured 15 gerbils using 31P nuclear magnetic resonance (NMR) spectroscopy 60-min 10% (0.5 g/kg; n=5), or 20% (1.0 compared those receiving saline (n=5). Gerbils anesthetized by intraperitoneal injection pentobarbital. Forebrain was induced clipping bilateral common...
The biological dosemeter that measures responses to ionising radiation is useful for protection. This paper presents the development and characterisation of a gamma ray irradiation dosimetry system based on real-time PCR (polymerase chain reaction) methodology. Real-time used amplify simultaneously quantify targeted DNA molecule. If there are no limitations due limiting substrates or reagents, at each extension step, amount target doubled, leading exponential (geometric) amplification...
Background: Gastrin is known to have stimulatory effects on gastric mucosa; however, long‐term effect of gastrin stimulation not well known. Aim and methods: To investigate the hypergastrinaemia, we established hypergastrinaemic transgenic mice by introducing a mutated human gene. Homozygously transgene‐expressing showed serum levels more than 600 pg/mL. Results: Neither progastrin nor glycine‐extended titre elevation were observed in mice. Stomachs from 30–35‐week‐old 30–50% heavier their...