A5070042050- Graphene and Nanomaterials Applications
- Neuroscience and Neural Engineering
- Magnetic and Electromagnetic Effects
- Spaceflight effects on biology
- Nerve injury and regeneration
- Electrohydrodynamics and Fluid Dynamics
- 3D Printing in Biomedical Research
- Conducting polymers and applications
- Micro and Nano Robotics
- Hydrogels: synthesis, properties, applications
- Environmental Engineering and Cultural Studies
- Characterization and Applications of Magnetic Nanoparticles
- Nanoparticle-Based Drug Delivery
- Lipid Membrane Structure and Behavior
- Anesthesia and Neurotoxicity Research
- Advanced Memory and Neural Computing
Consejo Superior de Investigaciones Científicas
2023-2025
Universidad Autónoma de Madrid
2025
Instituto de Ciencia de Materiales de Madrid
2021-2024
The combination of hydrogels and magnetic nanoparticles, scarcely explored to date, offers a wide range possibilities for innovative therapies. Herein, we have designed hybrid 3D matrices integrating natural polymers, such as collagen, chitosan (CHI) hyaluronic acid (HA), provide soft flexible networks mimicking the extracellular matrix tissues, iron oxide nanoparticles (IONPs) that deliver localized heat when exposed an alternating field (AMF). First, colloidally stable with hydrodynamic...
Progress in the clinical application of recording and stimulation devices for neural diseases is still limited, mainly because suboptimal material engineering unfavorable interactions with biological entities. Nanotechnology providing upgraded designs materials to better mimic native extracellular environment attain more intimate contacts individual neurons, besides allowing miniaturization electrodes. However, little progress has been done date on understanding impact that such interfaces...
Herein, we use two exemplary superparamagnetic iron oxide multicore nanoparticles (SPIONs) to illustrate the significant influence of slightly different physicochemical properties on cellular and molecular processes that define SPION interplay with primary neural cells. Particularly, have designed structures, NFA (i.e., a denser structure accompanied by less negative surface charge higher magnetic response) NFD larger area more negatively charged), identified specific biological responses...
Hydrogels and magnetic nanoparticles are by themselves attractive biomaterials for biomedical applications. The combination of both, scarcely explored to date, offers a wider range possibilities innovative therapies, including those in neural regeneration. In this study, we have designed hybrid 3D matrices integrating natural polymers, such as collagen, chitosan (CHI) hyaluronic acid (HA), provide soft flexible networks able mimic the extracellular matrix tissues, iron oxide (IONPs) that...