A5052392999- Neuroscience and Neuropharmacology Research
- Neurotransmitter Receptor Influence on Behavior
- Neuropeptides and Animal Physiology
- Receptor Mechanisms and Signaling
- Phosphodiesterase function and regulation
- Periodontal Regeneration and Treatments
- Synthesis and biological activity
- Dental Trauma and Treatments
- Railway Engineering and Dynamics
- Neuroendocrine regulation and behavior
- Magnetic Bearings and Levitation Dynamics
- Greenhouse Technology and Climate Control
- Memory and Neural Mechanisms
- Genetics and Neurodevelopmental Disorders
- Tribology and Lubrication Engineering
- Synthesis and Biological Evaluation
- Anesthesia and Neurotoxicity Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Autism Spectrum Disorder Research
- Treatment of Major Depression
- Mesenchymal stem cell research
- Refrigeration and Air Conditioning Technologies
- Heat Transfer and Optimization
- Dental Implant Techniques and Outcomes
- dental development and anomalies
Asia University
2022-2023
National Taiwan University
2003-2019
National Yang Ming Chiao Tung University
1998
Periodontitis, a chronic inflammatory disease caused by microbial communities carrying pathogens, leads to the loss of tooth-supporting tissues and is significant contributor tooth loss. This study aims develop novel injectable cell-laden hydrogel consisted collagen (COL), riboflavin, dental light-emitting diode (LED) photo-cross-linking process for periodontal regeneration. Utilizing α-SMA ALP immunofluorescence markers, we confirmed differentiation human ligament fibroblasts (HPLFs) into...
In present study we studied the cytotoxic effects of beta-lapachone, a potent anticancer drug, on human hepatoma cell line (HepA2) under serum-free condition. Most cells died after 2 microM beta-lapachone addition at 48 hours. No apoptotic characteristics DNA ladder was documented by agarose electrophoresis. The blockage cycle S phase and unscheduled synthesis were demonstrated flow cytometric analysis anti-bromodeoxyuridine immunocytochemistry. Ultrastructural observation showed that...
Symptoms of schizophrenia (SZ) typically emerge during adolescence to young adulthood, which gives a window before full-blown psychosis for early intervention. Strategies preventing the conversion from prodromal phase psychotic are warranted. Heterozygous (Het) Disc1 mutant mice considered model SZ, suitable studying conversion. We evaluated preventive effect chronic N-acetylcysteine (NAC) administration, covering prenatal era on reaction following Amph challenge, mimics outbreak or...
Abstract Disrupted‐in‐Schizophrenia 1 ( DISC1 ) is a susceptibility gene for several psychiatric illnesses. To study the pathogenesis of these disorders, we generated Disc1 mutant mice by introducing 129S6/SvEv 25‐bp deletion variants into C57BL/6J strain. In this study, used heterozygous (Het) to evaluate haploinsufficiency model schizophrenia. No changes in locomotor behaviors were observed Het mice; however, after amphetamine injection, greater activity was compared with wild‐type (WT)...
Periodontal ligament stem cells (PDLSCs) have the potential for regenerating periodontal tissue. The study aims to investigate impact of demographics (ages, gender, disease) and culture techniques (shipping storage time method) on success primary culture. PDLSCs were collected from 51 teeth 26 patients cultured via outgrowth (OG) enzymatic digestion (ED) methods. Cells characteristics confirmed by flow cytometry, MTT, ARS. rate was evaluated with a serial chi-square test determine...
Disrupted‐in‐Schizophrenia‐1 (DISC1) is a susceptibility gene for several psychiatric illnesses. To study the pathogenesis of these disorders, various Disc1 mutant mouse models were established. In our group, mice generated by introducing 129S6/SvEv 25‐bp deletion variants into C57BL/6J strain. this study, battery behavioral tests was conducted to evaluate phenotypes and cognitive function in heterozygous (Het) mice. open field test, novel object recognition Y‐maze prepulse inhibition no...
An integrated method that combines the first order plate theory, Hamilton’s principle, finite element and subspace iteration is used to calculate natural frequencies of thick rotating annular discs. The shear deformation rotary inertia elastic discs with uniform thickness are considered. Interactive software generated for personal computers, effects disc rotational speed, ratio outer radius inner on analyzed. Comparison calculated shows good correlation existing data. It expected this can...