A5100304526- Plant biochemistry and biosynthesis
- Virus-based gene therapy research
- Neuroinflammation and Neurodegeneration Mechanisms
- Genomics and Phylogenetic Studies
- Cancer Mechanisms and Therapy
- Endometrial and Cervical Cancer Treatments
- Natural Products and Biological Research
- Bacteriophages and microbial interactions
- Ovarian cancer diagnosis and treatment
- RNA modifications and cancer
- Cervical Cancer and HPV Research
- Heat Transfer Mechanisms
- Heat Transfer and Optimization
- Genetics, Aging, and Longevity in Model Organisms
- Sarcoidosis and Beryllium Toxicity Research
- Clinical Nutrition and Gastroenterology
- Breast Lesions and Carcinomas
- Sport Psychology and Performance
- Horticultural and Viticultural Research
- Heat shock proteins research
- Testicular diseases and treatments
- Molecular Biology Techniques and Applications
- Advanced Technologies in Various Fields
- Physiological and biochemical adaptations
- Chromatin Remodeling and Cancer
Anhui Medical University
2024-2025
Ruijin Hospital
2022-2025
Shanghai Jiao Tong University
2022-2025
Huzhou University
2025
The University of Texas MD Anderson Cancer Center
2023-2024
National University of Singapore
2024
Shenzhen Maternity and Child Healthcare Hospital
2024
Heilongjiang Bayi Agricultural University
2024
Xiangya Hospital Central South University
2023-2024
Central South University
2023-2024
Ischemic stroke (IS) is a dangerous cerebrovascular disorder with significant incidence and death rate. Ubiquitin-specific peptidase 18 (USP18) has been proven to mitigate ischemic brain damage; however, its potential regulatory mechanisms remain unclear. In vivo in vitro models of IS were established by middle cerebral artery occlusion (MCAO) oxygen-glucose deprivation/reoxygenation (OGD/R). Neurocyte injury was detected MTT, LDH, ROS level, mitochondrial membrane (Δψm), flow cytometry....
Abstract Perilla frutescens (L.) Britton, a member of the Lamiaceae family, stands out as versatile plant highly valued for its unique aroma and medicinal properties. Additionally, P. seeds are rich in Îś-linolenic acid, holding substantial economic importance. While nuclear chloroplast genomes have already been documented, complete mitochondrial genome sequence remains unreported. To this end, sequencing, annotation, assembly entire Mitochondrial were hereby conducted using combination...
Abstract Herb genomics, at the forefront of traditional Chinese medicine research, combines genomics with practices, facilitating scientific validation ancient remedies. This integration enhances public understanding medicine’s efficacy and broadens its scope in modern healthcare. Stachys species encompass annual or perennial herbs small shrubs, exhibiting simple petiolate sessile leaves. Despite their wide-ranging applications across various fields, molecular data have been lacking,...
Background Colorectal cancer (CRC) ranks among the most common gastrointestinal cancers globally, with both its incidence and mortality rates showing an upward trend. In particular, 5-year survival rate for stage IV CRC patients is only 14%. Conventional treatments such as chemotherapy immunotherapy can lead to drug resistance, exacerbate function damage, induce immunosuppression. Sijunzi decoction (SJZD), a fundamental formula of Traditional Chinese medicine (TCM), has been demonstrated...
ABSTRACT Existing evidence shows the importance of circulating cytokines in studying female reproductive system dysfunction. Endometriosis (EM) is thought to be associated with multiple immune cytokines, but its causality has not been proven. Utilising Genome‐Wide Association Study (GWAS) data, we performed Mendelian randomisation (MR) assess between 41 and EM. Positive Single Nucleotide Polymorphisms (SNPs) were annotated via Multi‐marker Analysis GenoMic Annotation (MAGMA) intersected...
College freshmen face a heightened risk of mental health problems. Recent research has extensively explored attachment and growth mindset as key factors that influence health. However, the specific relationship between remains unclear. This study aimed to investigate how impacts college students explore mindset, attachment, A survey 684 (80.1% female, average age 18.4) at university in Huzhou was conducted using Growth Mindset Scale, Adult Attachment Symptom Checklist (SCL-90) demographic...
Gap junctions play critical roles in tissue function and homeostasis. Connexin43 (Cx43) is a major gap junction protein expressed the mammalian heart other tissues may be regulated by its interaction with cellular proteins. Using yeast two-hybrid screen, we identified novel Cx43-interacting of 85-kDa, CIP85, which contains single TBC, SH3, RUN domain, addition to short coiled coil region. Homologues containing this unique combination domains were found human, D. melanogaster, C. elegans....
Abstract This paper analyzes the impact of changes in securities transaction tax (STT) rate on local A-share market China. We find that, average, a 22-basis-point increase STT is associated with about 28 percent drop trading volume, and 17-basis-point reduction an 89 volume Chinese market. Both increases reductions result significant volatility. In addition, have mixed effects efficiency, either improving or curbing it. Reductions usually make less efficient no effect The empirical results...
Risk stratification of gastrointestinal stromal tumors (GISTs) is based on experience with the stomach, small bowel, and rectum, which are far more common than GISTs other sites. In this study from 47 institutions, we analyzed esophagus (n = 102), colon 136), appendix 27) for their size, mitotic rate, morphology, outcome to determine criteria predict behavior. Esophageal were (median: 2.5 cm) spindle cell morphology a low rate (mean: 3.6/5 mm2). Twelve (12%) progressed, including 11 >5/5 mm2...
Abstract Nonsurgical management of ductal carcinoma in situ is controversial and little known about the long-term consequences this approach. In study, we aimed to determine risk (a) upstaging invasive at excision (b) ipsilateral breast cancer events patients who might have been eligible for nonsurgical DCIS trials. Data from women aged 20 years or older with a biopsy diagnosis between January 1, 2010 December 31, 2014 were collated. The underwent surgical resection (lumpectomy mastectomy)...
Comprehensive Summary Photocatalytic aerobic oxidative desulfurization (PAODS) is a sustainable alternative technology to traditional, energy‐intensive fuel methods. Nonetheless, its advancement hindered by the notable challenge of inadequate electron‐hole separation efficiency within existing catalytic systems. Herein, Janus 2D/2D heterostructure composed Co 3 O 4 and CoMoO reported for PAODS thiophenic sulfides. Through combination detailed experimental characterizations density functional...
Bone mesenchymal stem cell (BMSC)-derived exosome (BMSC-Exo) could be a treatment method for ischemic injury. In cerebrovascular disease (IC), microglia is pivotal in neuronal damage and remodeling. This study explores the mechanisms of BMSC-Exo miR-148b-3p regulating oxygen-glucose deprivation/reoxygenation (OGD/R)-induced human microglial clone 3 (HMC3) activation. Transmission electron microscopy (TEM) qNano were used to assess features. The functions miR-148 b-3p OGD/R-induced HMC3...
Frequencies of blood types A, B, and AB in domestic cats vary geographically among breeds have not been reported China.The purpose this study was to survey the frequency Beijing area.A total 262 from city were blood-typed using a standard tube agglutination assay. All nonpedigree shorthaired longhaired cats; purebred excluded. Serum obtained type-B lectin (Triticum vulgaris) solution served as anti-A anti-B reagents, respectively. The presence alloantibodies also determined some cats.The...
The mechanism of bacteriophage photoinactivation by methylene blue and light (MB+L) involves genomic RNA damage. In this study, two viruses, Sindbis virus (SINV) hepatitis C were treated MB+L their nucleic acids amplified to show that lesions occurred during inactivation. During inactivation, the viral load both viruses was significantly reduced as exposure increased. acid amplification inhibited in a time-dependent manner percentage inhibition reached about 99% after 30 min treatment....
Glioblastoma multiforme (GBM) is the most frequent and lethal cancer derived from central nervous system, of which mesenchymal (MES) subtype seriously influences survival prognosis patients. NAD(P)H: quinone acceptor oxidoreductase 1 (NQO1) serves an important role in carcinogenesis progression various types cancer; however, specific mechanism underlying regulatory effects NQO1 on GBM unclear. Thus, present study aimed to explore progression. The results bioinformatics analysis...
Invasive lobular carcinoma with papillary features is a newly proposed variant which presents as relatively well-circumscribed mass lesion at least partial peripheral thickened fibrous capsule and central delicate fibrovascular cores, morphologically mimicking encapsulated or solid carcinoma. There are only 5 cases described in literature. We here report an interesting example of invasive growth pattern surrounded by thick capsule, (EPC). The nature the tumor was confirmed absence membranous...