A5028692886- Fatty Acid Research and Health
- Metabolomics and Mass Spectrometry Studies
- Lipid metabolism and biosynthesis
- Echinoderm biology and ecology
- Peroxisome Proliferator-Activated Receptors
- Seaweed-derived Bioactive Compounds
- Cholesterol and Lipid Metabolism
- Autophagy in Disease and Therapy
- Aquaculture Nutrition and Growth
- Adipose Tissue and Metabolism
- Algal biology and biofuel production
- Marine Bivalve and Aquaculture Studies
- Marine Sponges and Natural Products
- Thermoregulation and physiological responses
- Diet and metabolism studies
- Glycosylation and Glycoproteins Research
- Mass Spectrometry Techniques and Applications
- Liver Disease Diagnosis and Treatment
- Clusterin in disease pathology
- Advanced Proteomics Techniques and Applications
- Eicosanoids and Hypertension Pharmacology
- Insect Utilization and Effects
- GDF15 and Related Biomarkers
- Dietary Effects on Health
- Sphingolipid Metabolism and Signaling
Qingdao University
2023-2025
Ocean University of China
2020-2024
This article systematically reviewed the proportion of ARA and DHA in breast milk formula among regions lactation periods, their impact on infant development health.
Ether-phospholipids (ether-PLs) in sea urchins, especially eicosapentaenoic-acid-enriched plasmenyl phosphatidylethanolamine (PE-P) and plasmanyl phosphatidylcholine (PC-O), exhibit potential lipid-regulating effects. However, their underlying regulatory mechanisms have not yet been elucidated. Herein, we integrated an untargeted lipidomics strategy biochemical analysis to investigate these high-fat-induced atherosclerotic hamsters. Dietary supplementation with PE-P PC-O decreased total...
A comprehensive lipidomic analysis was performed onto three edible brown seaweeds, namely Laminaria japonica, Undaria pinnatifida, and Scagassum natans, using reversed-phase liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (RPLC-Q-TOF-MS/MS). In total, 675 lipid molecules, including glycolipids (GLs), phospholipids, sphingolipids (SLs), betaine lipids, glycerolipids, were identified semiquantified. With the exception of high content diacylglycerols found in L....
Red seaweeds (Rhodophyta) are becoming increasingly important as a food and medicine source in blue biotechnology applications such functional foods, feeds, pharmaceuticals. Compared to fatty acid composition sterols, the lipidome red is still an early disclosure stage. In this study, lipidomes of four (Gracilaria sjoestedtii, Gracilaria verrucosa, Gelidium amansii, Chondrus ocellatus) collected from coastal area north China were characterized using reversed-phase liquid chromatography...
The total water intake was insufficient among older individuals over 75 in China, impacting their body composition, hydration status, and metabolism.
The sea cucumber plasmalogen PlsEtn has been shown to be associated with various chronic diseases related lipid metabolism. However, the mechanism is unclear. Therefore, present study used plasmanylcholine PakCho as a structural contrast and assessed its effect in 8 week high-fat diet (HFD)-fed mice. lipidomic approach based on high-resolution mass spectrometry combined molecular biology techniques was evaluate of PlsEtn. results showed that both significantly inhibited an increase mouse...
Untargeted metabolomics and biochemical analysis revealed that eicosapentaenoic acid-enriched sea cucumber ether-phospholipids attenuate oxidative stress, inflammation by restoration of fatty acid, BCAA TCA metabolism.
Echinoderms are of broad interest for abundant bioactive lipids. The comprehensive lipid profiles in eight echinoderm species were obtained by UPLC-Triple TOF-MS/MS with characterization and semi-quantitative analysis 961 molecular 14 subclasses 4 classes. Phospholipids (38.78-76.83%) glycerolipids (6.85-42.82%) the main classes all investigated species, ether phospholipids, whereas proportion sphingolipids was higher sea cucumbers. Two sulfated detected echinoderms first time; sterol...
Sea cucumber phospholipids have ameliorative effects on various diseases related to lipid metabolism. However, it is unclear whether can ameliorate obesity-associated glomerulopathy (ORG) induced by a high-fat diet (HFD). The present study applied UPLC-QqQ-MS/MS and atmospheric pressure matrix-assisted laser desorption ionization mass spectrometry imaging (AP-MALDI MSI) investigate the of sea phospholipids, including plasmalogen PlsEtn plasmanylcholine PakCho, phospholipid profiles in...
Dietary astaxanthin (AST) exhibits the ability to resist lipid accumulation and stimulate hepatic autophagy. Natural AST predominantly exists in stable esterified forms. More importantly, our previous study, docosahexaenoic acid-acylated monoester (AST-DHA) possessed better stability, bioavailability, neuroprotective than free diester form. However, AST-DHA mechanisms of action regulating obese phenotype autophagy central nervous system remain unclear.High-fat diet (HFD)-fed C57BL/6J mice...
Enteromorpha prolifera (EP) is a green alga that causes bloom worldwide. This study aimed to isolate and identify n-3 polyunsaturated fatty acids (PUFAs) from EP oil obtained via supercritical fluid extraction (SFE) explore its preventive effects against dextran sodium sulfate (DSS)-induced ulcerative colitis in C57BL/6J mice. In oil, we found the novel acid C16:4n-3 two unusual C18:4n-3 C16:3n-3, using GC-MS. The administration of reduced histopathological symptoms shortening colon length....
Sea urchin gangliosides are superior to GM1 and sialic acid in promoting neuronal differentiation synapse function of postnatal 15-day mice, via up-regulating the expressions BDNF NGF.