A5100686115- Crystallization and Solubility Studies
- MicroRNA in disease regulation
- X-ray Diffraction in Crystallography
- Infant Nutrition and Health
- CAR-T cell therapy research
- Catalytic Processes in Materials Science
- Advanced Photocatalysis Techniques
- Microbial Community Ecology and Physiology
- Immunotherapy and Immune Responses
- Cancer Immunotherapy and Biomarkers
- Metal-Organic Frameworks: Synthesis and Applications
- Hybrid Renewable Energy Systems
- Wastewater Treatment and Nitrogen Removal
- Cancer-related molecular mechanisms research
- Immune Cell Function and Interaction
- Extracellular vesicles in disease
- Fuel Cells and Related Materials
- Electrochemical Analysis and Applications
- RNA modifications and cancer
- Cancer Genomics and Diagnostics
- Geological and Geochemical Analysis
- Peptidase Inhibition and Analysis
- Natural Compounds in Disease Treatment
- Analytical Chemistry and Sensors
- Advanced oxidation water treatment
Nanjing Medical University
2011-2025
Guizhou Electric Power Design and Research Institute
2025
China University of Political Science and Law
2024
Institute of Process Engineering
2016-2024
Inner Mongolia Yili Industrial Group (China)
2016-2024
Tsinghua University
2018-2024
Anhui Jianzhu University
2020-2024
China University of Geosciences (Beijing)
2021-2024
Jiangnan University
2022-2024
Zhejiang University of Technology
2021-2024
Emerging evidence indicates that osteoclasts direct osteoblastic bone formation. MicroRNAs (miRNAs) have a crucial role in regulating osteoclast and osteoblast function. However, whether miRNAs mediate osteoclast-directed formation is mostly unknown. Here, we show increased osteoclastic miR-214-3p associates with both elevated serum exosomal reduced elderly women fractures ovariectomized (OVX) mice. Osteoclast-specific knock-in mice rescued by osteoclast-targeted antagomir-214-3p treatment....
Abstract Therapeutic antibodies that target T-cell co-inhibitory molecules display potent antitumor effects in multiple types of cancer. LSECtin is a cell surface lectin the DC-SIGN family expressed dendritic cells inhibits responses. limits activity infectious disease, but it has not been studied Here we report finding commonly melanomas where blunts tumor-specific When B16 melanoma cells, promoted tumor growth, whereas its blockade slowed growth either wild-type or LSECtin-deficient mice....
Herein, we, for the first time, report a high spin Co-Fe Prussian blue analogue (Co-Fe PBA) as highly efficient Fenton-like catalyst sulfate radical (SO4˙-) production. Our experiments and density functional theory (DFT) calculations show that largely elongated SO4-OH bond length, strengthened adsorption facilitated electron transfer peroxymonosulfate (PMS) activation catalyzed by high-spin (HS) CoII are main factors contributing to its excellent activity.
Milk fat globule membrane (MFGM) proteins have many functions. To explore the different proteomics of human and bovine MFGM, MFGM were separated from colostrum mature milk, analyzed by iTRAQ proteomic approach. A total 411 recognized quantified. Among these, 232 kinds differentially expressed identified. These based on multivariate analysis, gene ontology (GO) annotation KEGG pathway. Biological processes involved response to stimulus, localization, establishment immune system process....
Abstract Corrosion resistance to high temperature concentrated alkali solutions (>20 wt.%) is very important for 316L austenitic stainless steel (316L SS). Herein, the effect of (130℃) on corrosion behavior and passive film composition SS in 50 wt.% NaOH solution was investigated by electrochemical methods, XPS, AES. The results indicated that films significantly affected temperature. When increased from 40°C 130°C, current density two orders magnitude, number defects were also increased....
Electrochemical methods have been widely used to monitor physiologically important molecules in biological systems. This report describes the first application of scanning electrochemical microscope (SECM) probe redox activity individual living cells. The possibilities measuring rate and investigating pathway transmembrane charge transfer are demonstrated. By this approach, significant differences detected responses given by nonmotile, nontransformed human breast epithelial cells, cells with...
Crystal gazing: A mild solution route has been designed for the controlled synthesis of lead tungstate microcrystals with high crystal symmetry, in which cationic surfactant, pH value, and temperature play key roles. Helix- (see TEM image), spindle-, chainlike, dendritic structures can be produced by varying reaction conditions.
Thermodynamic parameters for GU pairs are important predicting the secondary structures of RNA and finding genomic sequences that code structured RNA. Optical melting curves were measured 29 duplexes with to improve nearest neighbor stabilities helixes. The updated model eliminates a prior penalty assumed terminal pairs. Six additional 5′GG/3′UU motif added single representation in previous database. This revises ΔG°37 from an unfavorable 0.5 kcal/mol favorable −0.2 kcal/mol. Similarly,...
// Jie Shen 1 , Qiang Hu 2,5 Michael Schrauder 6 Li Yan 2 Dan Wang Leonardo Medico 3 Yuqing Guo Song Yao Qianqian Zhu Biao Liu Maochun Qin Matthias W. Beckmann Peter A. Fasching Reiner Strick Candace S. Johnson 4 Christine B. Ambrosone Hua Zhao Department of Epidemiology, the University Texas MD Anderson Cancer Center, Houston, TX, USA Biostatistics & Bioinformatics, Roswell Park Institute, Buffalo, NY, Prevention and Control, Pharmacology Therapeutics, 5 Institute Basic Medical...
Renal cell carcinomas (RCCs) with t(6;11)(p21;q12) are extremely rare and characterized by specific chromosome translocation, involving the transcription factor EB (TFEB). Fewer than 30 cases have been described in literature. We examined 7 additional of this tumor clinicopathologic, immunohistochemical, molecular, ultrastructural analyses. Four tumors had typical morphologic features TFEB RCCs, whereas 3 demonstrated uncommon features, mimicking epithelioid angiomyolipoma, chromophobe RCC,...
Abstract The role of osteoclastic miRNAs in regulating osteolytic bone metastasis (OBM) breast cancer is still underexplored. Here, we examined the expression profiles osteoclastogenic human specimens and identified that miR-214-3p was significantly upregulated patients with OBM. Consistently, found increased within osteoclasts, which associated elevated resorption, during development OBM xenografted nude mice (BCX). Furthermore, genetic ablation prevent Conditioned medium from MDA-MB-231...
Whey, an essential source of dietary nutrients, is widely used in dairy foods for infants. A total 584 whey proteins human and bovine colostrum mature milk were identified quantified by the isobaric tag relative absolute quantification (iTRAQ) proteomic method. The 424 differentially expressed analyzed according to gene ontology (GO) annotation, Kyoto encyclopedia genes genomes (KEGG) pathway, multivariate statistical analysis. Biological processes principally involved biological regulation...
// Cheng Wang 1 , Biao Liu 2, * Xuelian Xu Bo Zhuang Hongxia Li Jiaqi Yin Mengyi Cong Wei 3, 4 Aiping Lu 2 Key Laboratory of Marine Drugs, Chinese Ministry Education, School Medicine and Pharmacy, Ocean University China, Qingdao, China Institute for Advancing Translational in Bone Joint Diseases, Jockey Club Building, Hong Kong Baptist University, Kowloon Tong, Kowloon, 3 Department Shandong Provincial Qian Foshan Hospital, Jinan, Division Molecular Pharmaceutics Center Nanotechnology Drug...