About
Contact & Profiles
A5016795005
Research Areas
- Sympathectomy and Hyperhidrosis Treatments
- Inflammasome and immune disorders
- Cardiovascular Syncope and Autonomic Disorders
- Phagocytosis and Immune Regulation
- Migraine and Headache Studies
- Immune cells in cancer
University of Southern California
2024
Tehran University of Medical Sciences
2019
Immune checkpoints (CTLA4 & PD-1) are inhibitory pathways that block aberrant immune activity and maintain self-tolerance. Tumors co-opt these to avoid destruction. checkpoint inhibitors (ICIs) activate cells restore their tumoricidal potential, making them highly efficacious cancer therapies. However, immunotolerant organs such as the liver depend on tolerogenic mechanisms, disruption with ICI use can trigger unintended side effect of hepatotoxicity termed immune-mediated injury from ICIs...
10.1038/s41419-024-06535-7
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Cell Death and Disease
2024-02-14
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