Yuma Tsukasa

ORCID: 0009-0007-3690-4000
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About
Contact & Profiles
Research Areas
  • Neurobiology and Insect Physiology Research
  • Insect and Arachnid Ecology and Behavior
  • Insect and Pesticide Research
  • Insect Utilization and Effects
  • Cancer Cells and Metastasis
  • Invertebrate Immune Response Mechanisms
  • Animal Disease Management and Epidemiology
  • HIV Research and Treatment
  • Insect Pest Control Strategies
  • Microtubule and mitosis dynamics
  • Cellular Mechanics and Interactions
  • Virus-based gene therapy research

Kyoto University
2022-2024

Appropriate modulation of escape behaviors in response to potentially damaging stimuli is essential for survival. Although nociceptive circuitry has been studied, it poorly understood how genetic contexts affect relevant responses. Using an unbiased genome-wide association analysis, we identified Ly6/α-neurotoxin family protein, Belly roll (Bero), which negatively regulates Drosophila behavior. We show that Bero expressed abdominal leucokinin-producing neurons (ABLK neurons) and bero...

10.7554/elife.83856 article EN cc-by eLife 2023-06-13

In vivo, cells collectively migrate in a variety of developmental and pathological contexts. Coordinated epithelial rotation represents unique type collective cell migrations, which has been modeled vitro under spatially confined conditions. Although it is known that the coordinated depends on intercellular interactions, contribution E-cadherin, major cell-cell adhesion molecule, not directly addressed two-dimensional (2D) substrates. Here, using well-controlled fibronectin-coated surfaces,...

10.1111/gtc.13001 article EN Genes to Cells 2022-12-23

ABSTRACT Ex vivo physiological experiments using small insect models such as Drosophila larvae have become increasingly useful to address fundamental biological questions. To perform experiments, various artificial saline solutions been developed, but their osmolality varies significantly from one the next. Such a variation of stems, in part, difficulty determining true value haemolymph larvae. Thus, there is pressing need refine protocols for collecting and measuring larval haemolymph. Two...

10.1242/jeb.247249 article EN publisher-specific-oa Journal of Experimental Biology 2024-04-15

Feline leukemia virus (FeLV) is a retrovirus that causes immune suppression and immunodeficiency, leading to opportunistic infections leukemia/lymphoma in cats. Today, variety of domestic mammals are kept houses, it important evaluate the possibility interspecies transmission FeLV. In this study, we assessed infectivity FeLV-B ferrets belong Mustelidae. By pseudotype infection assay, revealed ferret cell line, Mpf cells, resistant infection. The mRNA expression level receptor, Pit-1, was...

10.1292/jvms.22-0526 article EN Journal of Veterinary Medical Science 2023-01-01

ABSTRACT ex vivo physiological experiments using small insect models such as Drosophila larvae have become increasingly useful to address fundamental biological questions. To perform experiments, various artificial saline solutions been developed, but their osmolality varies significantly from one the next. Such a variation of stems, in part, difficulty determining true value haemolymph larvae. Thus, there is pressing need refine protocols for collecting and measuring larval haemolymph. Two...

10.1101/2023.12.25.573325 preprint EN cc-by-nc bioRxiv (Cold Spring Harbor Laboratory) 2023-12-26

Summary Appropriate modulation of escape behaviors in response to potentially damaging stimuli is essential for survival. Although nociceptive circuitry has been studied, it poorly understood how genetic contexts affect the relevant responses. Using an unbiased genome-wide association analysis, we identified a Ly6/α-neurotoxin family protein, Belly roll (Bero), which negatively regulates Drosophila behavior. We show that Bero expressed abdominal leucokinin-producing neurons (ABLK neurons)...

10.1101/2022.10.20.513010 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2022-10-21
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