A5103078715- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Advanced biosensing and bioanalysis techniques
- Crystallography and molecular interactions
- Protein Kinase Regulation and GTPase Signaling
- Traditional Chinese Medicine Analysis
- Neurological Disease Mechanisms and Treatments
- Chromatography in Natural Products
- Inflammatory Bowel Disease
- Freezing and Crystallization Processes
- Protease and Inhibitor Mechanisms
- Gut microbiota and health
- Phytochemicals and Antioxidant Activities
- Biosensors and Analytical Detection
- Ionic liquids properties and applications
- Cytokine Signaling Pathways and Interactions
- Liver Disease Diagnosis and Treatment
- Enzyme Production and Characterization
- Microscopic Colitis
- Polysaccharides Composition and Applications
- Biochemical effects in animals
- Liver physiology and pathology
- Meat and Animal Product Quality
- Advanced Nanomaterials in Catalysis
- Protein Hydrolysis and Bioactive Peptides
Soochow University
2024-2025
Qingdao University of Science and Technology
2011-2024
Nanjing General Hospital of Nanjing Military Command
2024
Jinan University
2018-2024
The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital)
2024
Tianjin University of Traditional Chinese Medicine
2023-2024
Panyu District Central Hospital
2023-2024
Southern University of Science and Technology
2020-2024
Nanjing Medical University
2024
First People's Hospital of Foshan
2023
Abstract The perturbations of the gut microbiota and metabolites are closely associated with progression inflammatory bowel disease (IBD). However, inconsistent findings across studies impede a comprehensive understanding their roles in IBD potential as reliable diagnostic biomarkers. To address this challenge, here we comprehensively analyze 9 metagenomic 4 metabolomics cohorts from different populations. Through cross-cohort integrative analysis (CCIA), identify consistent characteristic...
Background/aims To investigate the clinical features of Chinese patients with seropositive myelin oligodendrocyte glycoprotein antibody (MOG-Ab) optic neuritis (ON) and aquaporin-4 (AQP4-Ab) ON. Methods In this retrospective observational study, sera from demyelinating ON were tested for MOG-Ab AQP4-Ab a cell-based assay. Clinical characteristics compared between MOG-Ab-related (MOG-ON) AQP4-Ab-related (AQP4-ON), including visual performances, serum autoantibodies on MRI. Results A total 109...
Biocompatible materials with ice recrystallization inhibition (IRI) activity have potential applications in several fields. Emerging studies associated the IRI of antifreeze proteins/glycoproteins and mimics synthetic a facially amphipathic structure. Nanocelluloses are new family renewable that demonstrate amphiphilicity. Herein cellulose nanocrystals (CNCs) 2,2,6,6-tetramethylpiperidine-1-oxyl oxidized nanofibrils (TEMPO-CNFs) is reported. In 0.01 M NaCl, was effectively inhibited by 5.0...
The hepatoprotective activity of anthocyanin-rich purple sweet potato extract (APSPE) was demonstrated. Sixty mice were randomly divided into six groups: control group [without carbon tetrachloride (CCl4) or APSPE]; model (with CCl4 only); positive (50 mg/kg body weight silymarin); low-dose (100 APSPE); medium-dose (200 and high-dose (400 APSPE). After 10 days intragastric administration the respective supplements, in all groups except injected intraperitoneally with (0.15% arachis oil,...
Although the signaling pathways leading to hydrogen peroxide (H2O2)-induced endothelial monolayer permeability remain ambiguous, cytoskeletal proteins are known be essential for maintaining integrity and regulating solute flux through monolayer. We have recently demonstrated that thrombin-induced actin reorganization in bovine pulmonary artery cells (BPAEC) requires activation of both myosin light chain kinase (MLCK) protein C (PKC). Therefore, present study was designed investigate effects...
Neuroendocrine carcinoma (NEC) of the breast, a distinct type mammary whose terminology was not proposed until 2003, has been well recognized or studied. The aim our study is to evaluate clinicopathological features and outcomes this tumor. We conducted comparative on 107 NEC patients 475 invasive ductal carcinoma, otherwise specified(IDC, NOS) from Department Pathology, Huashan Hospital, Fudan University, determine demographic, pathological, clinical at presentation, along with patient...
Anthocyanins exhibit natural antioxidants but poor stability and low oil solubility. Therefore, increasing the fat solubility of anthocyanins is necessary to broaden their applications. In our experiment, an anthocyanin microemulsion system was constructed its investigated. At phase emulsifier ratio 7:3, hydrophilic oil-wet value reached 7.5 Km 2:1. Furthermore, area largest. The bicontinuous region exhibited optimal experimental conditions resulted in a containing 425.54 ± 1.58 μg/g...
Excess iron content can build up in the retina and lead to iron-mediated retinal injury. An important isoflavone C-glucoside, puerarin, has been reported be involved protection. In this experiment, we studied effects potential mechanisms of puerarin on injury vivo vitro. We found that reduced serum content, attenuated pathophysiological changes deposition, partially prevented decrease rhodopsin pigment epithelium-specific 65 kDa protein expression retinas iron-overload mice. Puerarin rescued...
This study investigates the protective effects of blueberry anthocyanins against acute liver injury. Cyanidin-3-glucoside, delphinidin-3-rutinoside, and malvidin-3-galactoside, main monomers among anthocyanins, play important roles in cell survival increasing level cellular antioxidant. Results proliferation assay showed that different concentrations protected human embryonic-liver L-02 cells CCl4-induced injury a dose-dependent manner. After 48 h incubation, cells, with IC50 6.2 × mg/L....
Abstract Sepsis is a systemic inflammatory response that may be induced by trauma, infection, surgery, and burns. With the aim of discovering novel treatment targets for sepsis, this current study was conducted to investigate effect potential mechanism which microRNA‐30a (miR‐30a) controls sepsis‐induced liver cell proliferation apoptosis. Rat models sepsis were established applying cecal ligation puncture (CLP) method simulate models. The binding site between miR‐30a suppressor cytokine...
Abstract This study draws upon organizational psychology and platform labor research to investigate how socio‐psychological factors affect the mental well‐being of workers help them cope with challenges work. Based on a survey 500 food‐delivery (‘riders’) in China, we provide quantitative evidence workers' ambivalent subjective experiences that complements predominantly qualitative account extant literature. In particular, assess complex relationships between meaningfulness work, autonomy at...