A5110592960- Reconstructive Surgery and Microvascular Techniques
- Acupuncture Treatment Research Studies
- Urological Disorders and Treatments
- Microplastics and Plastic Pollution
- Ferroptosis and cancer prognosis
- Acute Ischemic Stroke Management
- Trace Elements in Health
- Air Quality and Health Impacts
- Tissue Engineering and Regenerative Medicine
- Clusterin in disease pathology
- Wound Healing and Treatments
- Cancer survivorship and care
- Aortic aneurysm repair treatments
- Lung Cancer Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Traumatic Brain Injury and Neurovascular Disturbances
- Sexual function and dysfunction studies
- Aortic Disease and Treatment Approaches
- Intracerebral and Subarachnoid Hemorrhage Research
- Dermatologic Treatments and Research
- Lipid metabolism and disorders
- Neurosurgical Procedures and Complications
- Congenital Heart Disease Studies
- biodegradable polymer synthesis and properties
- Axon Guidance and Neuronal Signaling
Huazhong Agricultural University
2024-2025
Chengdu Third People's Hospital
2025
Southwest Jiaotong University
2025
North China Electric Power University
2025
Chengdu University of Traditional Chinese Medicine
2019-2025
Development Research Center
2024
Guangzhou University of Chinese Medicine
2024
Lanzhou University Second Hospital
2024
Chengdu University
2023-2024
Sichuan Center for Disease Control and Prevention
2024
Scope Age‐related increases in retinal iron are involved the development of degeneration. The recently discovered iron‐dependent mechanism cell death known as ferroptosis has been linked to a wide range pathologies. However, its role overload‐induced degeneration is still uncertain. Puerarin associated with protection. purpose this research determine how puerarin prevents under overload conditions. Methods and results Models Kunming mice, 661W cell, ARPE‐19 established. Increased deposition...
This study directly aligns with Sustainable Development Goals (SDGs), i.e., SDG-13 and SDG-4. Carbon emissions (CO2e) are primarily addressed under SDG-13: Climate Action, which aims to combat climate change its impacts. CO2e reduction efforts contribute achieving this goal by mitigating greenhouse gas emissions. SDG 4: Quality Education ensure inclusive equitable quality education for all. It emphasizes explicitly lifelong learning opportunities targets higher (HE) access improve skills...
Excess iron content can build up in the retina and lead to iron-mediated retinal injury. An important isoflavone C-glucoside, puerarin, has been reported be involved protection. In this experiment, we studied effects potential mechanisms of puerarin on injury vivo vitro. We found that reduced serum content, attenuated pathophysiological changes deposition, partially prevented decrease rhodopsin pigment epithelium-specific 65 kDa protein expression retinas iron-overload mice. Puerarin rescued...
Background and Purpose— The INTEnsive blood pressure Reduction in Acute Cerebral hemorrhage Trial (INTERACT) pilot study showed that early intensive pressure-lowering can attenuate hematoma growth acute intracerebral hemorrhage. present analysis aimed to determine the treatment effects on by time from onset randomization. Methods— Patients (N=404) with elevated systolic were randomly assigned or guideline-based management. Baseline repeat CT (24 72 hours) performed changes volume assessed...
Both the accumulation of reactive oxygen species (ROS) and iron overload are significant variables that enhance incidence photoreceptor cell death retinal degeneration. The discovery ferroptosis, which is characterized by iron-dependent lipid peroxidation, has led to a new perspective on how degeneration develops. As natural phenolic acid, salvianic acid A (SAA) from Salvia miltiorrhiza promise in treating eye diseases. purpose this research was learn more about SAA its function development...
Insomnia (difficulty falling or staying asleep) is a common issue among breast cancer survivors, significantly impacting their quality of life. Current treatments, primarily pharmacological and psychological, have limitations: the former often causes side effects, while latter faces accessibility barriers. Long-snake moxibustion (LSM), traditional Chinese medicine (TCM) technique, involves applying along governor vessel, which an important meridian in TCM that plays key role regulating brain...
Background Cancer-related fatigue (CRF) is one of the most prevalent and debilitating symptoms experienced by breast cancer survivors, often associated with dysregulation hypothalamic-pituitary-adrenal (HPA) axis. In China, moxibustion widely used as a therapeutic approach for managing fatigue. Thunder-fire (TFM), novel technique high thermal radiation strong penetrative properties, may provide benefits CRF. This study aims to assess efficacy, safety, underlying mechanisms TFM in treatment...
The effects of Bi modification on the microstructural development and gyromagnetic properties low-temperature sintered ferrites with composition Li0.42Zn0.27Ti0.11Mn0.1Fe2.1−xBixO4 (x = 0.0-0.1) have been studied in order to adapt cofired ceramics technology (LTCC) produce devices a multilayer process. In present work, pure spinel phase can be formed sintering temperature ranging from 880°C 900°C, which allows them co-fired silver. We found that Bi3+ ions could enter into ferrite lattice,...
The phosphatidylinositol 3–kinase (PI3K) signaling pathway is critical in modulating platelet functions. In the present study, we evaluated effect of S14161, a recently identified pan-class I PI3K inhibitor, on activation and thrombus formation. Results showed that S14161 inhibited human aggregation induced by collagen, thrombin, U46619, ADP dose-dependent manner. Flow cytometric studies convulxin- or thrombin-induced P-selectin expression fibrinogen binding single platelet. also spreading...
Abstract Cardiorenal syndrome type 4 (CRS4), a progressive deterioration of cardiac function secondary to chronic kidney disease (CKD), is leading cause death in patients with CKD. In this study, we aimed investigate the cardioprotective effect emodin on CRS4. C57BL/6 mice 5/6 nephrectomy and HL‐1 cells stimulated 5% CKD mouse serum were used for vivo vitro experiments. To assess potential emodin, employed comprehensive array methodologies, including echocardiography, tissue staining,...
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8606 Background: Amivantamab (Ami) is a bispecific antibody targeting EGFR and MET tyrosine kinase receptors with immune cell-directing activity. The phase 3 PAPILLON study (NCT04538664) investigated the combination of Ami carboplatin/pemetrexed (ACP) vs. (CP) as first-line treatment in patients (pts) advanced Exon20ins-mutated NSCLC. ACP improved progression free survival (PFS) both overall population Asian subgroup. Methods: Pts were randomized 1:1 to or CP. primary endpoint was PFS by...
This study aimed to investigate the efficacy and mechanism of action Governor Vessel Moxibustion (GVM) in treatment Cancer-Related Fatigue (CRF) patients who have completed for colorectal cancer. We randomly assigned 80 CRF a 1:1 ratio either experimental group or control group. During three-week period, both groups received usual care provided by professional nurses. The additional GVM (three times week, nine total). primary outcome was mean change total fatigue score from baseline end...