A5013924987- Plant Virus Research Studies
- Nanoparticle-Based Drug Delivery
- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- Hepatocellular Carcinoma Treatment and Prognosis
- Plant-Microbe Interactions and Immunity
- Pediatric health and respiratory diseases
- MicroRNA in disease regulation
- Plant pathogens and resistance mechanisms
- Iron Metabolism and Disorders
- Icing and De-icing Technologies
- Characterization and Applications of Magnetic Nanoparticles
- Antibiotic Use and Resistance
- HIV, TB, and STIs Epidemiology
- Endoplasmic Reticulum Stress and Disease
- Pneumonia and Respiratory Infections
- Neonatal and Maternal Infections
- Marine Biology and Environmental Chemistry
- Pesticide Exposure and Toxicity
- Computational Drug Discovery Methods
- Enterobacteriaceae and Cronobacter Research
- Respiratory viral infections research
- Insect Utilization and Effects
- Effects of Radiation Exposure
- Liver physiology and pathology
Taizhou People's Hospital
2017-2024
Nantong University
2017-2024
Huazhong Agricultural University
2020-2024
Shanghai Zhangjiang Laboratory
2024
Nanjing Medical University
2024
Jilin Medical University
2023
Changchun University of Chinese Medicine
2018-2022
Shandong Center for Disease Control and Prevention
2012-2017
Shandong University
2011
Centers for Disease Control and Prevention
2009
With the progress of nanotechnology and molecular biology, nanoparticles have been widely studied applied in biomedicine. Particularly, characterized by unique magnetic property, targeting, biocompatibility, become one research hotspots nanomedical field. Herein, we summarized recent advances medicine, including carrier function, MRI, tumor inductive hyperthermia nanoparticles.
To improve antibiotic use globally, we must deepen our understanding of the public's knowledge, attitudes and practices (KAP) concerning antibiotics. Children are frequent users antibiotics, their caregivers play important roles in determining how antibiotics used. The purpose this study was to describe caregivers' KAP a rural province eastern China, identify socio-demographic factors associated with inappropriate use. A cross-sectional questionnaire based survey conducted 12 villages one...
Background: With the development of new magnetic resonance imaging (MRI) techniques, an increasing number articles have been published regarding hepatocellular carcinoma (HCCMRI) in past decade. However, few studies statistically analyzed these articles. In this study, we aim to systematically evaluate scientific outcomes HCCMRI research and explore hotspots from 2008 2017. Methods: The included 2017 were downloaded Web Science Core Collection verified by two experienced radiologists. Excel...
Sclerotinia sclerotiorum and Botrytis cinerea are typical necrotrophic pathogens that can attack more than 700 3000 plant species, respectively, cause huge economic losses across numerous crops. In particular, the absence of resistant cultivars makes stem rot because S. major threat rapeseed (Brassica napus) worldwide along with Botrytis. Previously, we identified an effector-like protein (SsSSVP1) from a homologue SsSSVP1 on B. genome found could interact BnQCR8 rapeseed, subunit cytochrome...
Angiotensin-I-converting enzyme (EC 3.4.15.1; ACE) plays an important physiological role in the regulation of blood pressure by converting angiotensin I to II, a potent vasoconstrictor. Therefore, ACE inhibition has become major target control for hypertension. Pipefish, or hailong, is essential traditional Chinese medicine that widely used anti-fatigue and anti-cancer. A recent study found two ACE-inhibitory peptides (TFPHGP HWTTQR) purified from seaweed pipefish Alcalase enzymatic...
Via virome sequencing, six viruses were detected from Magnaporthe oryzae strains YC81-2, including one virus in the family Tombusviridae, Narnaviridae and four Botourmiaviridae. Since RNA-dependent RNA polymerase (RdRp) of botourmiavirus show highest identity (79%) with ourmia-like 1 (MOLV1), that was grouped into genus Magoulivirus designated as 2 (MOBV2). The three other novel botourmiaviruses selected for further study. complete nucleotide sequences determined. Sequence analysis showed 1,...
Fructus Gardeniae (FG) is medicine food widely used for the treatment and prevention of various diseases. However, in recent years, research has suggested that high doses FG can cause hepatotoxicity nephrotoxicity. To assess this potential toxicity more depth, study investigated effects decocted two its bioactive constituents (geniposide genipin) on liver kidney function rats. Rats were intragastrically administered (330 mg/kg body weight), geniposide (50 or genipin weight) 12 weeks. Changes...
This study was performed to investigate the biocompatibility (BC), magnetothermal effect, and DNA binding biological characteristics of manganese zinc ferrite nanoparticles (Mn 0.6 Zn 0.4 Fe 2 O 4 -NPs (MZF-NPs)) coated with pegylated (PEG-MZF-NPs). Their functions as gene transfer carrier for therapy magnetic medium tumor hyperthermia were also explored. The synthesized through high temperature cracking, their characterizations discovered. Hemolysis test MTT assay evaluate biocompatibility,...
The seed microbiota is an important component given by nature to plants, protecting seeds from damage other organisms and abiotic stress. However, little known about the dynamic changes potential functions of during development. In this study, we investigated composition rapeseed (Brassica napus). A total 2496 amplicon sequence variants (ASVs) belonging 504 genera in 25 phyla were identified, all sampling stages divided into three groups. flower buds, young pods, at 20 days after flowering...
Magnetic nanomaterials have recently emerged, playing an increasingly essential role in life science and biomedicine fields, they exhibited promising potentials cancer diagnosis therapy. Also, their use as contrast agents improved various diagnostic imaging sensitivities accuracy. are also exploited targeted drug carriers to increase the sensitivity reduce side effects of chemotherapeutic drugs. Herein, we reviewed preparation, characterization, surface modification magnetic therapy applications.
Purpose: This study aimed to construct targeting drug-loading nanocomposites (FA-FePt/DDP nanoliposomes) explore their potential in ovarian cancer therapy and molecular magnetic resonance imaging (MMRI). Methods: FA-FePt-NPs were prepared by coupling folate (FA) with polyethylene-glycol (PEG)-coated ferroplatinum nanoparticles characterized. Then cisplatin (DDP) was encapsulated synthesize FA-PEG-FePt/DDP nanoliposomes thin film-ultrasonic method high-speed stirring, of which MMRI potential,...
ABSTRACT The precise delineation of glioma tumors is paramount importance for surgical and radiotherapy planning. Presently, the primary drawbacks associated with manual segmentation approach are its laboriousness inefficiency. In order to tackle these challenges, a deep learning‐based automatic technique was introduced enhance efficiency process. We proposed ADT‐UNet, an innovative algorithm segmenting in MR images. ADT‐UNet leveraged attention‐dense blocks Transformer as foundational...
This article analyzes the current system, prevention and treatment team, drugs relating to AIDS control with traditional Chinese medicine, relevant policies in China so as provide scientific advice on improving promote role of medicine treating AIDS.
：Objective To explore theepidemic characteristics of bacterial dysentery in Jinan municipality, and to providescientific basis for effective strategy control. Methods Theepidemiolagical bacillary from 1951 2005 wereanalyzed. A total 485 333 cases the span 50 years were recorded, while thepopulation-based case distribution was less than due dataincompleteness during Cultural Revolution. Results The incidence bacillarydysentery has been decreasing by with average rate 283.10/100000.The...
Our previous findings showed a good therapeutic effect of the combination suicide gene HSV-TK, nuclide 131I, and magnetic fluid hyperthermia (MFH) on hepatoma by using nanoparticles as linkers, far better than any monotherapy involved, with no adverse effects. This therapy might be an eligible strategy to treat hepatic cancer. However, it is not clear how regimen took In current study, explore possible mechanisms radionuclide-gene combined MFH at tissue, cellular, molecular levels provide...
Objective To find out the status of prevention and control iodine deficiency disorders evaluate nutritional Jinan residents,to explore appropriate level in drinking water,and to provide a scientific basis for adjustment intervention strategies.Methods According Monitoring Program National Iodine Deficiency Disorders (Trial),qualified iodized salt consumption rate,drinking water content urinary levels women childbearing age were determined areas from 2003 2010.Salt was detected by direct...