Tatyana S. Ostapova

ORCID: 0009-0007-4193-6680
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About
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Research Areas
  • HIV Research and Treatment
  • HIV/AIDS drug development and treatment
  • HIV/AIDS Research and Interventions
  • Hepatitis C virus research
  • Liver Disease Diagnosis and Treatment
  • Hepatitis B Virus Studies
  • HIV, TB, and STIs Epidemiology
  • Monoclonal and Polyclonal Antibodies Research
  • Blood groups and transfusion
  • Bacteriophages and microbial interactions
  • Bacillus and Francisella bacterial research

Centre for Prevention and Control of AIDS and Infectious Diseases
2024

Regional Center for Prevention and Control of AIDS and Infectious Diseases
2020-2023

More than a quarter of HIV-infected individuals registered in Russia live Siberia. Unlike Central where HIV-1 subtype A6 is predominant, most Siberian regions since 2012, new CRF63_02A1 genetic variant has spread, with the share this attaining 75–85% among newly identified HIV cases. Krasnoyarsk Krai considered to be high-risk territory according morbidity rate and infection incidence population. The current paper aims study molecular epidemiologic characteristics spreading Krai....

10.1155/2020/9057541 article EN cc-by BioMed Research International 2020-09-10

HIV-1 epidemic in Russia is one of the fastest growing world reaching 1.14 million people living with (PLWH) 2021. Since mid-1990s, has started to grow substantially due multiple outbreaks among persons who inject drugs (PWID) leading expansion sub-subtype A6 (former Soviet Union (FSU) subtype A). In 2006, a local sub-epidemic caused by distribution novel genetic lineage CRF63_02A6 was identified Siberia. this study, we used comprehensive dataset pol gene sequences investigate spatiotemporal...

10.3389/fmicb.2022.946787 article EN cc-by Frontiers in Microbiology 2022-08-31

To research the molecular genetic characteristics of HCV population circulating among HIV‐infected residents Krasnoyarsk Territory, including analysis resistance‐associated mutations to NS5A inhibitors. Total RNA was isolated from 94 blood plasma samples HIV/HCVinfected region and nucleotide sequences Core/E1 gene regions were obtained deciphered, which used for genotyping searching resistance mutations. In studied, circulation five virus subtypes recorded: 1b (47,9 %), 3a (37,2 1a (10,6 2a...

10.18470/1992-1098-2024-1-4 article EN cc-by South of Russia ecology development 2024-04-07

Though hundreds of thousands papers are currently being published on HIV/AIDS, only tens them devoted to the antibodies generated during disease. Most these discuss in HIV/AIDS as a diagnostic tool, and some articles describe neutralizing promising treatment. In this paper, we used affinity chromatography ELISA isolate natural IgG from blood 26 HIV-infected patients. preparations were separated into subfractions containing different types light chains, catalytic activities analyzed. Here,...

10.3390/life12020304 article EN cc-by Life 2022-02-17
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