A5033442167- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Reproductive System and Pregnancy
- Cardiovascular Issues in Pregnancy
- Cancer Risks and Factors
- Prenatal Screening and Diagnostics
- Lymphatic System and Diseases
- Maternal and fetal healthcare
- Neonatal Respiratory Health Research
- Preterm Birth and Chorioamnionitis
- Fetal and Pediatric Neurological Disorders
- Gestational Trophoblastic Disease Studies
- Biomarkers in Disease Mechanisms
- Inflammatory mediators and NSAID effects
- Autopsy Techniques and Outcomes
- Anesthesia and Pain Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Pregnancy and Medication Impact
- Lymphatic Disorders and Treatments
- Endometrial and Cervical Cancer Treatments
- Pregnancy-related medical research
- Hormonal Regulation and Hypertension
- Ectopic Pregnancy Diagnosis and Management
- Neonatal and Maternal Infections
- Sympathectomy and Hyperhidrosis Treatments
AZ Groeninge
2020-2025
KU Leuven
2003-2016
Universitair Ziekenhuis Leuven
1995-2011
University of Nottingham
1983-1985
Northern General Hospital
1983
Queen's Medical Centre
1983
John Radcliffe Hospital
1976
University of Oxford
1976
ABSTRACT Objective To investigate trophoblast invasion and vascular changes in placental bed spiral arteries normal severe pre‐eclamptic pregnancies. Design A histological immunohistochemical study of biopsies containing arteries. Setting The University Hospital, Leuven, Belgium. Subjects Twenty‐one from 21 pregnancies 24 pregnancies, taken at caesarean section. Observations Histological appearance (stained with haematoxylin eosin), periodic acid schiff, a monoclonal antibody to low...
BACKGROUNDThe current techniques for quantifying trophoblast viability, migration and invasion are mainly limited by the need to sacrifice cells during test procedure. In this study, vital dye AB (AB) was used quantify cell number viability of BeWo JEG-3 choriocarcinoma cells, as well their through fibronectin-coated filters.
<b>Objective</b> To evaluate the incidence of serious maternal complications after use various tocolytic drugs for treatment preterm labour in routine clinical situations. <b>Design</b> Prospective cohort study. <b>Setting</b> 28 hospitals Netherlands and Belgium. <b>Participants</b> 1920 consecutive women treated with tocolytics threatened labour. <b>Main outcome measures</b> Maternal adverse events (those suspected being causally related to were considered drug reactions) leading cessation...
In Brief Combined spinal epidural analgesia (CSE) for labor pain relief has become increasingly popular. However, the effect of intrathecal sufentanil on incidence uterine hyperactivity and fetal heart rate (FHR) abnormalities remains controversial. We hypothesized that use in a dose 7.5 μg is more likely to induce nonreassuring FHR tracing than small combined with bupivacaine or analgesia. Three-hundred parturients were randomized into three groups. first group, was initiated 12.5 mg...
Abstract Objectives To compare prospectively maternal acceptance of fetal and neonatal virtuopsy with that conventional autopsy to determine the confidence which magnetic resonance (MR) can be used diagnose normality/abnormality various anatomical structures. Methods MR and/or computed tomography were offered 96 women (102 fetuses/neonates) following termination pregnancy (TOP), intrauterine death (IUFD) or death. Multivariable logistic regression analysis was investigate effect on age...
When added to decongestive lymphatic therapy (DLT), what is the effect of fluoroscopy-guided manual drainage (MLD) versus traditional MLD or placebo for treatment breast cancer-related lymphoedema (BCRL)?Multicentre, three-arm, randomised controlled trial with concealed allocation, intention-to-treat analysis and blinding assessors participants.At five hospitals in Belgium, 194 participants unilateral chronic BCRL were recruited.All received standard DLT (education, skin care, compression...
Although cervical carcinoma is among the most frequently encountered malignancies during pregnancy, only four cases of neoadjuvant chemotherapy pregnancy have been reported. A 28-year-old A0P1G2M0 was diagnosed at 15 weeks with stage Ib1 invasive squamous cancer. Because she strongly desired continuation this after extensive counseling treated 75 mg/m(2) cisplatin every 10 days starting 17 weeks. After six cycles, clinically and radiologically stable disease normalization cell tumor marker...
The interactions of trophoblasts with the cytokine network at fetomaternal interface determine pathway cell undertakes, e.g. proliferation, differentiation and apoptosis.We used cultures fusigenic BeWo non-fusigenic JEG-3 choriocarcinoma cells to study effects inducers syncytialisation (forskolin) apoptosis [tumour necrosis factor-alpha (TNFalpha)] on differentiation, viability, proliferation apoptosis.E-cadherin immunostaining showed that syncytium formation was confined not cells, while...
The aim of this study was to evaluate the diagnostic reliability and prognostic significance quantification cytomegalovirus (CMV) DNA in amniotic fluid (AF). We retrospectively reviewed results for 282 samples that had been tested CMV by a quantitative real-time PCR. observed three cases which no genomes were detected AF but children nevertheless congenitally infected. Hence, we conclude negative result PCR cannot rule out possibility congenital infection. No false-positive observed. A...
Objectives We aimed to assess the prevalence of uterine rupture in Belgium and evaluate risk factors, management outcomes for mother child. Design Nationwide population-based prospective cohort study. Setting Emergency obstetric care. Participation 97% maternity units covering 98.6% deliveries Belgium. Participants All women with between January 2012 December 2013. 8 were excluded because data collection forms not returned. Results Data on 90 cases confirmed obtained, which 73 had a previous...
The objective of this trial was to investigate the effectiveness fluoroscopy-guided manual lymph drainage (MLD), as part decongestive lymphatic therapy (DLT), on superficial architecture in patients with chronic mild moderate breast cancer-related lymphoedema (BCRL). This a multicentre, double-blind, randomised controlled involving 194 participants BCRL. Participants were into (1) DLT MLD (intervention group), (2) traditional (control or (3) placebo (placebo group). Superficial evaluated...
The level of protection against SARS-CoV-2 breakthrough infections conferred by the presence anti-S1 antibodies (IgGs) in cancer patients is still understudied. This work examines existence an immunoglobulin G (IgG) -based correlate (CoP) established prospectively collected observational data about with different variants a large cohort study vaccinated patients. 760 were longitudinally followed-up, starting before first vaccination until six months after second booster. Anti-S1 IgGs...
Cancer-related cognitive impairment (CRCI) is a prevalent source of comprised quality life in cancer survivors. This study evaluated the efficacy Emotional Freedom Techniques (EFT) on self-reported CRCI (sr-CRCI).
A retrospective review of obstetric anaesthesia charts was performed for all parturients receiving regional over a 22-month period. The incidence headache, post dural puncture headache (PDPH) and various other complications that had been prospectively assessed were noted, as the anaesthetic technique used (epidural or combined spinal epidural (CSE)). PDPH rare (0.44%) occurred with similar frequency in those managed either CSE analgesia. pencil-point needle gauge (27 29) did not influence...
We appreciate the commentary by Pierre Bourgeois [...]
The purpose of this study was to investigate the effectiveness fluoroscopy-guided manual lymph drainage (MLD) versus that traditional and placebo MLD, when added decongestive lymphatic therapy (DLT) for treatment breast cancer-related lymphedema (BCRL) (EFforT-BCRL trial), on suprafascial accumulation fluid skin elasticity.In multicenter, 3-arm, double-blind, randomized controlled trial 194 participants (mean age = 61 [SD 10] years) with unilateral BCRL were recruited. All received...