A5068880684- Molecular Spectroscopy and Structure
- Advanced Chemical Physics Studies
- Cervical Cancer and HPV Research
- Health Systems, Economic Evaluations, Quality of Life
- Inorganic Fluorides and Related Compounds
- Prostate Cancer Diagnosis and Treatment
- Cancer Treatment and Pharmacology
- Global Cancer Incidence and Screening
- Atmospheric Ozone and Climate
- Genetic factors in colorectal cancer
- PI3K/AKT/mTOR signaling in cancer
- Colorectal Cancer Treatments and Studies
- Glioma Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Hepatitis B Virus Studies
- Molecular spectroscopy and chirality
- Pancreatic and Hepatic Oncology Research
- Healthcare Policy and Management
- Lung Cancer Treatments and Mutations
- Cancer Genomics and Diagnostics
- Endoplasmic Reticulum Stress and Disease
- Brain Metastases and Treatment
- Economic and Financial Impacts of Cancer
- Gastric Cancer Management and Outcomes
- Fluorine in Organic Chemistry
Chongqing University
2024-2025
Henan Cancer Hospital
2024
Zhengzhou University
2024
GlaxoSmithKline (United States)
2020
Millennium Engineering and Integration (United States)
2018
Takeda (United States)
2018
Ariadne Diagnostics (United States)
2017
Roche (United States)
2013
Beckman Coulter Foundation
2011
Roche (Switzerland)
2009
The rotational spectra of 1,2-dihydronaphthalene (1,2-DHN), 1,4-dihydronaphthalene (1,4-DHN), and 1,2,3,4-tetrahydronaphthalene (1,2,3,4-THN) were measured analyzed. A single conformation was detected for each molecule. measurements the parent isotopologues extended to include all mono-substituted 13C 1,2-DHN 1,4-DHN. Through analysis experimental spectra, constants quartic centrifugal distortion accurately determined. skeletal structures 1,4-DHN derived based on constants. precise...
The C–H⋯S–S interactions are fundamentally important to understand the stability of biomacromolecules and their binding with small molecules, but they still underappreciated. Herein, we characterized in model molecular complexes. rotational spectra complexes diethyl disulfide CH2CH2 CH2CHF were measured analyzed. All detected structures mainly stabilized by a hydrogen bond, providing stabilization energies 2.3–7.2 kJ mol−1. Incidental C–H⋯π or C–H⋯F enhance London dispersion, which accounts...
The noncovalent interactions between formamide (FM) and the heteroaromatic compounds (furan thiophene) were investigated through microwave spectroscopy theoretical calculations. Each of complexes exhibits a single rotational spectrum corresponding to lowest energy structure predicted theoretically. In detected structures, N-H···O C-H···O hydrogen bonds dominate complexation FM furan, resulting in planar configuration. Conversely, superposed configuration linked by N-H···π bond C═O···π...
2007 Background:. The background rate of CNS hemorrhage (CH) in cancer patients with brain metastases not receiving bevacizumab (BV) treatment is 5%-29%, depending on tumor type. Patients were routinely excluded from most BV late-stage clinical trials, following the occurrence CH one hepatocellular carcinoma patient occult metastasis a phase I trial. In this particular tumour type, up to 87.5% has been reported as without use. Available safety information BV-treated reviewed determine...
The rotational spectroscopy of the diethyl disulfide and CH 2 F complex reveals bonding feature C–H⋯S–S hydrogen bond its predominant role in stabilizing complex.
1050 Background: Endocrine therapy for ER+ breast cancer is effective and relatively nontoxic, but limited by de novo acquired resistance. Preclinical studies suggest that complete ER blockade along with inhibition of co-expressed growth factor receptors enhances endocrine response overcomes Methods: We conducted a phase II trial combined anastrazole fulvestrant gefitinib, an EGFR tyrosine kinase inhibitor, as intial in postmenopausal women locoregional or metastatic cancer. A tumor core...