A5081688712- Pharmacological Effects of Natural Compounds
- Plant-based Medicinal Research
- Computational Drug Discovery Methods
- Pancreatic and Hepatic Oncology Research
- Gastroesophageal reflux and treatments
- Potassium and Related Disorders
- Cancer Genomics and Diagnostics
- Helicobacter pylori-related gastroenterology studies
- Ultrasound and Hyperthermia Applications
- Lung Cancer Treatments and Mutations
Qingdao Municipal Hospital
2024
Qingdao University
2024
Nanjing University of Chinese Medicine
2020-2022
The KUNPENG study aimed to evaluate the efficacy and safety of vebreltinib (also known as bozitinib, APL-101, PLB-1001, CBT-101), a potent highly selective inhibitor c-mesenchymal-epithelial transition (MET), in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) harboring c-Met alterations. This multicenter, multicohort, open-label, single-arm, phase II trial enrolled dysregulated, NSCLC from January 2020 August 2022 across 17 centers. Cohort 1 included MET exon...
Abstract Background: Coronavirus disease 2019 (COVID-19) is an emerging and rapidly evolving with no effective drug treatment. Traditional Chinese medicines have been widely used to treat COVID-19 in China. Chansu its major active constituent, bufalin, exert broad-spectrum antiviral effects. Although the clinical efficacy of injection for treatment has confirmed, mechanism action remains unclear. Objectives: In this study, we network pharmacology molecular docking technology explore...
Abstract Background : Coronavirus disease 2019 (COVID-19) is an emerging and rapidly evolving with no effective drug treatment. Traditional Chinese medicines have been widely used to treat COVID-19 in China. Chansu its major active constituent, bufalin, exert broad-spectrum antiviral effects. Although the clinical efficacy of injection for treatment has confirmed, mechanism action remains unclear. Objectives In this study, we network pharmacology molecular docking technology explore...