A5102762132- EEG and Brain-Computer Interfaces
- Muscle activation and electromyography studies
- Transcranial Magnetic Stimulation Studies
- Neural dynamics and brain function
- Functional Brain Connectivity Studies
- Heart Rate Variability and Autonomic Control
- Anomaly Detection Techniques and Applications
- Neural Networks and Applications
- Neuroscience and Neural Engineering
- Spinal Cord Injury Research
- Motor Control and Adaptation
- Neuroendocrine Tumor Research Advances
- Fractal and DNA sequence analysis
- Advanced Neuroimaging Techniques and Applications
- Cancer-related cognitive impairment studies
- Epilepsy research and treatment
- Circular RNAs in diseases
- Advanced Computational Techniques and Applications
- Cleft Lip and Palate Research
- Advanced MRI Techniques and Applications
- Advanced Decision-Making Techniques
- Renal Diseases and Glomerulopathies
- Neuroscience and Neuropharmacology Research
- Cancer-related molecular mechanisms research
- Face and Expression Recognition
State Key Laboratory of Respiratory Disease
2024
Guangzhou Medical University
2024
Shandong Academy of Sciences
2023
Qilu University of Technology
2023
Yunnan University
2022
Chengdu University of Traditional Chinese Medicine
2020
Cleveland Clinic
2005-2019
Columbia University Irving Medical Center
2019
Columbia University
2019
Shandong First Medical University
2019
Voluntary muscle fatigue is a progressive process. A recent study demonstrated fatigue-induced weakening of functional corticomuscular coupling measured by coherence between the brain [electroencephalogram (EEG)] and [electromyogram (EMG)] signals after relatively long-duration contraction. Comparing EEG-EMG before versus or data two time blocks not adequate to reveal dynamic nature The purpose this was address issue quantifying single-trial EEG, EMG power based on wavelet transform. Eight...
Motor patterns in legged vertebrates show modularity both young and adult animals, comprising motor synergies or primitives. Are such spinal modules observed mammals conserved into adulthood altered? Conceivably, early circuit alter radically through experience descending pathways' activity. We analyze lumbar of intact rats the same after transection compare these with transected 5 days postnatally, before most experience, using only that never developed hind limb weight bearing. use...
Abstract The RNA-dependent RNA polymerase (RdRp), 3C-like protease (3CL pro ), and papain-like (PL ) are pivotal components in the viral life cycle of SARS-CoV-2, presenting as promising therapeutic targets. Currently, all FDA-approved antiviral drugs against SARS-CoV-2 RdRp or 3CL inhibitors. However, mutations causing drug resistance have been observed from which makes it necessary to develop antivirals with novel mechanisms. Through application a structure-based design (SBDD) approach, we...
Enhanced activation in the non-lesion hemisphere stroke patients was widely observed during movement of affected upper limb, but its functional role related to motor planning and execution is still unknown. This study characterize by localizing sources high-density electroencephalography (EEG) signal estimating source strength (current density [A/m2]). Ten individuals with chronic shoulder/elbow coordination deficits 5 healthy controls participated study. EEG (64 channels) recorded from...
Background . Cisplatin is widely used in the treatment of malignant patients; however, its adverse nephrotoxic effects limit clinical use. Ginsenoside Rh1 a main component ginseng and has many pharmaceutical effects, including immunomodulatory effects. Objective The objective this research to assess ginsenoside on cisplatin‐induced HK‐2 injury model study potential effect mechanisms. Methods cell vitality was assessed via Cell Counting Kit‐8 (CCK‐8) assay. Carboxyfluorescein succinimidyl...
Deep learning has been popular for a few years, and it shows great capability on unsupervised leaning of representation. belief network consists multi layers restricted Boltzmann machine(RBM) deep auto-encoder, which uses stack architecture feature layer by layer. The rule is that one deeper learns more complex representations, are the high level features input data, from representations learnt before. Fuzzy C-Means(FCM) most clustering algorithms, allows piece data belong to several...
This study was to characterize dynamic source strength changes estimated from high-density scalp electroencephalogram (EEG) at different phases of a submaximal voluntary muscle contraction. Eight healthy volunteers performed isometric handgrip contractions the right arm 20% maximal intensity. Signals force, electromyography (EMG) finger flexor and extensor muscles 64-channel EEG were acquired simultaneously. Sources analyzed 19 time points across preparation, execution sustaining handgrip. A...
Background and Purpose . Cancer-related fatigue (CRF) is widely recognized as one of the most common symptoms side effects cancer and/or its treatment. However, neuropathological mechanisms contributing to CRF are largely unknown, lack knowledge makes difficult treat. Recent research has shown dissociation between changes in brain muscle signals during voluntary motor performance survivors with CRF, this may be caused by an interruption functional coupling (FC) two signals. The goal study...
The purpose of this study was to develop and online evaluate an effective feature-extraction method for distinguishing signal patterns scalp EEG during imageries left right hand movements. Time-frequency template based on Morlet wavelet decomposition event-related (de) synchronization extracted from two electrodes. matching index calculated correlation coefficient with the template, which further classified by linear discriminant analysis classifier distinguish imagined 9-subject left/right...
Fuzzy C-means clustering algorithm (FCM) is widely applied to the intrusion detection. To acquire a better division for data, new method (DEFCM) presented in paper which combines FCM and differential evolution (DE) found application. As start, several randomly initiated partitions are optimized by FCM, then result provided algorithm. After that, combined sent again adjust partition obtain final answer. The can improve detection performance effectively. KDDCUP1999 data set used simulation...
Objective To summarize the effects of deep brain stimulation(DBS) in treatment refractory epilepsy. Methods Engaged reading foreign references recent years from 2000 to 2014, with key words ofdeep stimulation, epilepsy, which are related stimulation for epilepsy at Pubmed and Ovid Medline database. Results The mechanism DBS prevent seizures is probably regulating cortical electric activities by structures. Animal clinical studies have stimulated anterior nucleus thalamus,...
The novel scheme of data fusion is a kind evidence theories based on distance. We calculate the weight coefficients according to structure network and distances matrix between points sensors. greater distance is, smaller coefficient will be. Experimental results show that, proposed algorithm works well with high conflicts fits characteristics network.
Gout is directly related to hyperuricemia caused by purine metabolism disorder and/or reduced uric acid excretion, and belongs the category of metabolic rheumatism. Currently, there are many drugs on market for treatment gout, but most them chemical synthetic drugs. The main direction targeted at gout attacks inhibit enzyme action or use hormones relieve pain during attacks, control cytokine/inflammatory cell movement function reduce inflammatory response. in interphase chronic phase mainly...
Objective To discuss the application of flexible sphenoidal electrodes in long-term electroencephalogram (EEG) monitoring infant rats. Methods A total 30 male Wistar rats were randomly divided into two groups: sphenoidal-electrode group and traditional-electrode (n=15). Status epilepticus was induced all animals by intraperitoneal injection lithium pilocarpine. Two weeks later, implanted with those home-made electrodes; video-EEG performed for weeks. The quantity seizures rate...