A5012041629- Colorectal Cancer Treatments and Studies
- Cancer Treatment and Pharmacology
- Enhanced Recovery After Surgery
- Cardiac, Anesthesia and Surgical Outcomes
- MicroRNA in disease regulation
- Intensive Care Unit Cognitive Disorders
- Pain Management and Opioid Use
- Hepatocellular Carcinoma Treatment and Prognosis
- Kruppel-like factors research
- Gastric Cancer Management and Outcomes
- Genetic Syndromes and Imprinting
Hebei Medical University
2024-2025
Fourth Hospital of Hebei Medical University
2024-2025
195 Background: In patients with advanced colorectal cancer (CRC), the recommended second-line treatment following first-line therapy oxaliplatin-based regimens is irinotecan-based therapy. Liposomal irinotecan, a novel formulation of traditional has demonstrated potential to enhance efficacy while minimizing toxicity. This study aims investigate and safety liposomal irinotecan in combination 5-FU/LV bevacizumab as option for metastatic CRC. Methods: multi-center, single-arm, prospective,...
In this study, we aimed to investigate the molecular mechanism of Krüppel-like factor 7 (KLF7) in colorectal cancer (CRC) cell invasion and migration. The expression pattern KLF7 CRC tissues correlation between clinical symptoms were analyzed. lines transfected with si-KLF7, followed by qRT-PCR or western blot detection KLF7, miR-139-5p, tumor protein D52 (TPD52) expression, counting kit-8 (CCK-8) assay detect viability, transwell Chromatin immunoprecipitation (ChIP) analyzed enrichment...