A5006835208- Mesenchymal stem cell research
- Gestational Diabetes Research and Management
- Sirtuins and Resveratrol in Medicine
- Genetic and phenotypic traits in livestock
- FOXO transcription factor regulation
- Effects of Environmental Stressors on Livestock
- Fatty Acid Research and Health
- Optimism, Hope, and Well-being
- Liver Disease Diagnosis and Treatment
- Pancreatic function and diabetes
- Ruminant Nutrition and Digestive Physiology
- Pregnancy and preeclampsia studies
Jouf University
2022-2025
Mesenchymal stem cells (MSCs) are multipotent stromal with remarkable plasticity, enabling them to differentiate into various tissue-specific cell types. MSCs play a pivotal role in tissue repair, hematopoiesis and immunomodulation. This study aimed evaluate compare the protective effects of olive leaf extract (OLE), bone marrow-derived mesenchymal (BM-MSCs) their combination against hepatic splenic toxicity rat model gestational diabetes induced by streptozotocin (STZ). Histopathological...
Background/Aims: Gestational Diabetes Mellitus (GDM) is a common complication during pregnancy, defined as diabetes diagnosed in the second or third trimester, often asymptomatic. This study investigates therapeutic potential of olive leaf extracts and stem cells mitigating GDM-induced complications, particularly focusing on renal function, oxidative stress, pancreatic cell regeneration. Methods: Measurements were made gravid female rats with without intraperitoneal administration...
Abstract Background/Aims: Gestational Diabetes Mellitus (GDM), a prevalent complication in pregnancy, is characterized by the Association as diabetes diagnosed second or third trimester, often remaining asymptomatic. This study investigates intricate effects of Streptozotocin on pregnant rats, unraveling its impact Type 2 (GTD). The research delves into potential therapeutic roles mesenchymal stem cells (MSCs) and olive leaf extract (OLE) mitigating consequences Streptozotocin-induced...
Background: Atherosclerosis represents one of the major causes morbidity in children with β-thalassemia (β-TM). Aim: This study was designed to investigate SIRT1-FOXO1 signaling β-TM and their role early detection premature atherosclerosis. Methods: We equally subdivided 100 Egyptian aged 6–14 years according carotid intima media thickness (CIMT) into 50 CIMT < 0.5 mm ≥ mm, healthy matched age were included. They subjected evaluation SIRT1, heat shock protein 72 (HSP72), hepcidin levels...