Shaohan Zhang

ORCID: 0009-0007-7304-9824
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Research Areas
  • Toxic Organic Pollutants Impact
  • Wound Healing and Treatments
  • Microplastics and Plastic Pollution
  • Effects and risks of endocrine disrupting chemicals
  • Electrospun Nanofibers in Biomedical Applications
  • Per- and polyfluoroalkyl substances research
  • Air Quality and Health Impacts
  • Advanced Drug Delivery Systems
  • Environmental Chemistry and Analysis
  • Hydrogels: synthesis, properties, applications
  • Recycling and Waste Management Techniques
  • Carcinogens and Genotoxicity Assessment
  • Nanoparticle-Based Drug Delivery
  • Lipid Membrane Structure and Behavior
  • Analytical chemistry methods development
  • Pregnancy and preeclampsia studies
  • Birth, Development, and Health
  • Extraction and Separation Processes
  • Odor and Emission Control Technologies
  • 3D Printing in Biomedical Research
  • Antimicrobial agents and applications
  • Venous Thromboembolism Diagnosis and Management
  • Indoor Air Quality and Microbial Exposure
  • Water Quality Monitoring and Analysis
  • Sirtuins and Resveratrol in Medicine

Nankai University
2022-2025

First Affiliated Hospital of GuangXi Medical University
2023

Guangxi Medical University
2023

Sun Yat-sen University
2018-2021

Aromatic amine antioxidants (AAs), extensively used in rubber products, and their ozone-photolyzed product p-phenylenediamine quinones (PPD-Qs) were found to be pervasive various environments with potential ecological health risks. The relationship between external internal exposure these contaminants risks the general population remain poorly explored. Herein, dust–handwipe–urine samples (n = 97 pairs) from families Tianjin, China was collected for analyzing 20 AAs 6 PPD-Qs (including...

10.1021/envhealth.3c00205 article EN cc-by-nc-nd Environment & Health 2024-02-19

Oxidative damage generated would disrupt the oxidant/antioxidant balance in cells, causing slow wound healing and tissue regeneration. Hydrogel dressing with antioxidant properties can promote healing, however, its design is still a challenge.

10.1039/c9bm00991d article EN Biomaterials Science 2019-01-01

During wound healing, the overproduction of reactive oxygen species (ROS) can break cellular oxidant/antioxidant balance, which prolongs healing. The dressings targeting mitigation ROS will be great advantages for puerarin (PUE) and ferulic acid (FA) are natural compounds derived from herbs that exhibit multiple pharmacological activities, such as antioxidant anti-inflammatory effects. Polydopamine (PDA) is made dopamine shows excellent function. Therefore, combination antioxidants into...

10.1186/s12951-021-00973-7 article EN cc-by Journal of Nanobiotechnology 2021-08-11

Liquid crystal monomers (LCMs) are a class of emerging, persistent, bioaccumulative, and toxic organic pollutants. They detected in various environmental matrixes that associated with electronic waste (e-waste) dismantling. However, their occurrence distribution indoor outdoor dust on national scale remain unknown. In this study, dedicated target analysis quantified broad range 60 LCMs samples collected across China. The were frequently (n = 48) 97; 37 sampled concomitantly indoors dust)...

10.1016/j.envint.2022.107295 article EN cc-by-nc-nd Environment International 2022-05-11

Liquid crystal monomers (LCMs) are widely used chemicals and ubiquitous emerging organic pollutants in the environment, some of which have persistent, bio-accumulative, toxic potentials. Elevated levels LCMs been found e-waste dismantling associated areas. However, information on their internal exposure bio-monitoring is scarce. For first time, occurrences were observed serum samples occupational workers (n = 85) from an area South China. Twenty-nine detected workers, with a median value...

10.1016/j.envint.2022.107535 article EN cc-by-nc-nd Environment International 2022-09-20

Liquid crystal monomers (LCMs) are indispensable materials in liquid displays, which have been recognized as emerging persistent, bioaccumulative, and toxic organic pollutants. Occupational nonoccupational exposure risk assessment suggested that dermal is the primary route for LCMs. However, bioavailability possible mechanisms of to LCMs via skin absorption penetration remain unclear. Herein, we used EpiKutis 3D-Human Skin Equivalents (3D-HSE) quantitatively assess percutaneous nine LCMs,...

10.1021/acs.est.2c07844 article EN Environmental Science & Technology 2023-03-03

Recently, evidence of aromatic amine antioxidants (AAs) existence in the dust electronic waste (e-waste) dismantling area has been exposed. However, there is limited studies investigating occupational exposure and toxicity associated with AAs their transformation products (p-phenylenediamines-quinones, i.e., PPD-Qs). In this study, 115 42 hand wipe samples collected from an e-waste recycling industrial park central China were analyzed for 19 6 PPD-Qs. Notably, median concentration ∑6PPD-Qs...

10.1016/j.envint.2024.108609 article EN cc-by-nc Environment International 2024-04-01

Transdermal drug delivery is an attractive, non-invasive treatment.

10.1039/c8tb01466c article EN Journal of Materials Chemistry B 2018-01-01

Embryonic and fetal development can be affected during gestation by exposure to xenobiotics that cross the placenta. Liquid crystal monomers (LCMs) are emerging contaminants commonly found in indoor environments; however, whether they placenta affect placental remains unexplored. Here, we develop an evaluation system integrates human biomonitoring, uterine perfusion pregnant rats, cells. We find fourteen out of fifty-six LCMs detected maternal cord serum samples from ninety-three healthy...

10.1038/s41467-025-56552-z article EN cc-by-nc-nd Nature Communications 2025-01-31

Root uptake is a primary pathway for pesticides to enter the plants; however, their mechanisms and biotransformation behaviors are still lacking. Herein, root of 21 triazole fungicides in rice plants (Oryza sativa L.) by hydroponic experiments were investigated. The triazoles roots may directly mainly originate from adsorption surface, not dominated nutrient solution. A QSAR model revealed that molecular descriptors related log Kow polarizability (e.g., ALogP ATSC6p) closely associated with...

10.1021/acs.jafc.5c00895 article EN Journal of Agricultural and Food Chemistry 2025-04-25

Early exercise for acute deep venous thrombosis (DVT) improves the patient's symptoms and does not increase risk of pulmonary embolism. However, information about its effect on thrombus resolution is limited. The aim this study was to investigate role resistance (RE) in recanalization determine underlying mechanisms. METHODS: Ninety-six C57BL/6 J mice were randomly divided into four groups: Control group (C, n = 24); DVT (D, RE + (ED, inhibitor (IED, 24). A model induced by stenosis inferior...

10.1186/s12872-022-02908-y article EN cc-by BMC Cardiovascular Disorders 2023-01-13

Abstract Background During wound healing, the overproduction of reactive oxygen species (ROS) can break cellular oxidant/antioxidant balance, which prolongs healing. The dressings targeting mitigation ROS will be great advantages for puerarin (PUE) and ferulic acid (FA) are natural compounds derived from herbs that exhibit multiple pharmacological activities, such as antioxidant anti-inflammatory effects. Polydopamine (PDA) is made dopamine shows excellent function. Therefore, combination...

10.21203/rs.3.rs-460628/v1 preprint EN cc-by Research Square (Research Square) 2021-05-05
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