Xuhua Xu

ORCID: 0009-0007-7383-0047
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About
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Research Areas
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Acute Ischemic Stroke Management
  • Neurosurgical Procedures and Complications
  • Dementia and Cognitive Impairment Research
  • MRI in cancer diagnosis
  • Frailty in Older Adults
  • Metabolomics and Mass Spectrometry Studies
  • Smart Parking Systems Research
  • Indoor and Outdoor Localization Technologies
  • Advanced Chemical Sensor Technologies
  • Health, Environment, Cognitive Aging
  • Forest Insect Ecology and Management
  • Neurological and metabolic disorders
  • Bioinformatics and Genomic Networks
  • Fermentation and Sensory Analysis
  • Alzheimer's disease research and treatments
  • Cellular transport and secretion
  • Hereditary Neurological Disorders
  • Endoplasmic Reticulum Stress and Disease
  • Approximation Theory and Sequence Spaces
  • Computational Drug Discovery Methods
  • Neurological Disease Mechanisms and Treatments
  • Robotics and Sensor-Based Localization
  • Plant Pathogens and Fungal Diseases
  • Educational Technology and Assessment

Zhejiang University
2017-2024

Sichuan University
2021-2023

Chongqing University
2022

Second Affiliated Hospital of Zhejiang University
2022

Guangdong Ocean University
2021

Shanghai Jiao Tong University
2012-2014

Previous studies have demonstrated altered metabolites in samples of Alzheimer's disease (AD) patients. However, the sample size from many them is relatively small and are limited. Here we applied a comprehensive platform using ultraperformance liquid chromatography-time-of-flight mass spectrometry gas to analyze plasma AD patients, amnestic mild cognitive impairment (aMCI) normal controls. A biomarker panel consisting six (arachidonic acid, N,N-dimethylglycine, thymine, glutamine, glutamic...

10.1021/pr5000895 article EN Journal of Proteome Research 2014-04-02

Given the increasing prevalence of dementia, any intervention that can effectively slow deterioration cognitive function is great importance.This study investigated efficacy a human-computer interaction-based comprehensive training program in cognitively impaired elderly individuals living nursing home.All subjects, who were aged ≥70 years and had impairment, randomly allocated to an group (n = 19) or control 14). The received for 24 weeks. Neuropsychological examinations conducted before...

10.3233/jad-130158 article EN Journal of Alzheimer s Disease 2013-06-18

Background and purpose: Remote diffusion-weighted imaging lesions (R-DWILs) have been detected in patients with spontaneous intracerebral hemorrhage (ICH), may be correlated clinical outcome. However, the mechanisms characteristics of R-DWILs not fully elucidated. In this study, we sought to demonstrate ICH. Methods: We prospectively collected data ICH from November 2016 December 2017. these patients, cerebral magnetic resonance (MRI) was performed within 28 days after onset. R-DWIL defined...

10.3389/fneur.2018.00209 article EN cc-by Frontiers in Neurology 2018-04-06

Hereditary sensory neuropathy (HSN) comprises a group of progressive peripheral neuropathies predominantly affecting the nerves. To date, two different ATL3 gene mutations have been reported to be responsible for HSN type 1F (HSN1F). Here, we report family in which members presented numbness lower limbs and recurrent foot ulceration. Symptoms ulcers disappeared years after onset, suggests that showed benign mild symptoms compared with affected patients previously. Laboratory examinations...

10.1111/jns.12309 article EN Journal of the Peripheral Nervous System 2019-01-25

Abstract Aims To explore the relationship between circulating neutrophil‐to‐lymphocyte ratio (NLR) and remote diffusion‐weighted imaging lesions (R‐DWILs) after spontaneous intracerebral hemorrhage (ICH). Methods Consecutive patients with ICH were prospectively collected from November 2016 to May 2018 retrospectively analyzed. We included subjects who presented within 24 hours symptom onset free of detectable infections on admission or in hospital. Blood samples obtained at 24‐48 ictus,...

10.1111/cns.13249 article EN cc-by CNS Neuroscience & Therapeutics 2019-10-25

Background: The prevalence of cognitive impairment (CI) and its associated risk factors among elderly peoples in China has been investigated. However, dynamic studies revealing the with decline from follow-up observa

10.3233/jad-131514 article EN Journal of Alzheimer s Disease 2014-02-14

Objective: Remote diffusion-weighted imaging (DWI) lesions (R-DWIL) found in intracerebral hemorrhage (ICH) patients are considered as an additional marker of cerebral small vessel disease (cSVD). This study aimed to investigate the association renal dysfunction and R-DWIL, well total burden cSVD on magnetic resonance among with primary ICH. Methods: One hundred twenty-six consecutive were prospectively enrolled. R-DWIL imaging, other markers cSVD, including lacunes, white matter lesions,...

10.3389/fnagi.2018.00171 article EN cc-by Frontiers in Aging Neuroscience 2018-06-07

In order to overcome the large positioning error of indoor garage caused by fuzzy scene texture, an localization method in weak texture is proposed. The divided into two stages: off-line and on-line. stage aims establish database parking lot number world coordinates marked corners. online stage, image preprocessed first, then improved Hough transform algorithm used extract feature points are matched according identified space number, combined with coordinate information corners stored...

10.1117/12.2637083 article EN 2022-06-15

Objective The aim of this study was to examine the association between remote diffusion-weighted imaging lesions (R-DWILs) and blood pressure variability (BPV) in patients with primary intracerebral hemorrhage (ICH). Methods We conducted a retrospective review consecutive cohort 375 ICH within 24 h onset. R-DWILs were defined as hyperintensity DWI from hematoma. Blood recordings extracted up post-admission. BPV measured using SD, coefficient variation (CV), successive (SV). Results Remote...

10.3389/fneur.2022.950056 article EN cc-by Frontiers in Neurology 2022-09-20

Traditional ideological and political education sets educational goals intuitively based on subjective experience, lacks logical reasoning experimental data support. In this paper, a large amount of is collected, the processed by smoothing techniques, entropy weight method used to rank research individuals. The results showed that highest score in urban group was 96.418, lowest 9.783, rural 97.569, 8.711.Then cluster analysis divide two groups into four categories, show better than region...

10.1145/3650400.3650591 article EN Proceedings of the 2021 5th International Conference on Electronic Information Technology and Computer Engineering 2023-10-20

Based on the modified ideal algorithm model, through MATLAB programming and SPASS software, study motivation of college students is analyzed classified. The weight vector .

10.1145/3656766.3656804 article EN 2023-11-24

According to the physical and chemical indexes of different periods, storage containers sites, a two overall T test was used show that there were significant differences in liquor body detection sites. Correlation analysis wine methods by Spearman correlation coefficient. By using principal component method, comprehensive evaluation index system quality constructed, classification model location based on established system. The sites classified, results showed divided into four grades.

10.26689/jcer.v5i3.1941 article EN Journal of Contemporary Educational Research 2021-04-02
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