Shuxian Zhang

ORCID: 0009-0007-7405-9215
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About
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Research Areas
  • Stroke Rehabilitation and Recovery
  • Functional Brain Connectivity Studies
  • Gout, Hyperuricemia, Uric Acid
  • Transcranial Magnetic Stimulation Studies
  • Corneal surgery and disorders
  • Ocular Surface and Contact Lens
  • Ophthalmology and Visual Impairment Studies
  • Carcinogens and Genotoxicity Assessment
  • Effects and risks of endocrine disrupting chemicals
  • Migraine and Headache Studies
  • Analytical Chemistry and Chromatography
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Biochemical Analysis and Sensing Techniques
  • Radiopharmaceutical Chemistry and Applications
  • RNA modifications and cancer
  • Eicosanoids and Hypertension Pharmacology
  • Circular RNAs in diseases
  • Microbial Community Ecology and Physiology
  • Analytical chemistry methods development
  • Genetic Neurodegenerative Diseases
  • MicroRNA in disease regulation
  • Autophagy in Disease and Therapy
  • Polyamine Metabolism and Applications
  • Pluripotent Stem Cells Research
  • Spatial Neglect and Hemispheric Dysfunction

Third Affiliated Hospital of Sun Yat-sen University
2020-2025

Sun Yat-sen University
2018-2025

Weifang Medical University
2015-2025

Ningxia Medical University
2023-2025

Chinese Academy of Sciences
2020-2025

Tianjin Medical University
2022-2024

Tianjin Medical University Eye Hospital
2022-2024

Nankai University
2022-2024

Shenyang Agricultural University
2024

University of Chinese Academy of Sciences
2020-2024

Irisin is a novel hormone secreted by myocytes. Lower levels of irisin are independently associated with endothelial dysfunction in obese subjects. The objective this study was to explore whether exerts direct vascular protective effect on function high-fat-diet-induced mice. Male C57BL/6 mice were given chow or high-fat diet without treatment irisin. Aortic determined measuring endothelium-dependent vasodilatation (EDV). Nitric oxide (NO) the aorta determined. AMP-activated protein kinase...

10.1152/ajpheart.00443.2015 article EN AJP Heart and Circulatory Physiology 2015-09-15

Objective: We aimed to interrogate the effects of transcranial magnetic stimulation (TMS) on performance in activities daily living (ADL) and attention function after stroke. Design: Randomized controlled trial. Setting: Inpatient rehabilitation hospital. Subjects: randomized 62 stroke patients with dysfunction who were randomly assigned into two groups, dropped out from each group. The TMS group ( n = 29) a sham 29), whose mean (SD) was 58.12 (6.72) years. A total 33 (56.9%) had right...

10.1177/0269215520946386 article EN Clinical Rehabilitation 2020-08-04

Per- and polyfluoroalkyl substances (PFAS) are extensively utilized in varieties of products tend to accumulate the human body including umbilical cord blood embryos/fetuses. In this study, we conducted an assessment comparison potential early developmental toxicity perfluorooctanoic acid (PFOA), undecafluorohexanoic (PFHxA), heptafluorobutyric acid, perfluorooctanesulfonate (PFOS), perfluorohexanesulfonate, perfluorobutyric at noncytotoxic concentrations relevant exposure using models based...

10.1021/acs.est.3c10758 article EN Environmental Science & Technology 2024-04-30

Abstract Background Post‐ischemic stroke executive impairment (PISEI) is a serious obstacle for patients to returning their society and currently difficult screen early clinically ineffective. Aim The aim of the study was clarify whether functional near‐infrared spectroscopy (fNIRS) can be used as rapid screening tool PISEI explore efficacy transcranial magnetic stimulation (TMS) in changes brain function. Methods A single‐blind, randomized controlled design detect hemodynamic differences by...

10.1111/cns.14118 article EN cc-by CNS Neuroscience & Therapeutics 2023-02-14

Transcranial alternating current stimulation (tACS) is a non-invasive technique that modulates neural oscillations, yet its specific effects on cortical excitability are not well-understood. This study investigated the of tACS neuroplasticity in primary motor cortex (M1) across different frequencies. In this randomized, sham-controlled, crossover study, 18 healthy young adults received β-tACS γ-tACS, and sham over M1. Neurophysiological responses were assessed using evoked potentials (MEPs),...

10.1186/s12984-025-01610-2 article EN cc-by-nc-nd Journal of NeuroEngineering and Rehabilitation 2025-03-27

Abstract Objective To evaluate whether patients with tension‐type headache (TTH) exhibit abnormal brain functional connectivity compared to healthy controls. Background TTH is one of the most prevalent disorders throughout world. The present study delves into in enhance understanding its underlying pathophysiology. Methods A cross‐sectional was conducted, enrolling diagnosed line International Classification Headache Disorders, 3rd edition beta criteria and a cohort controls (HCs). We used...

10.1111/head.14900 article EN Headache The Journal of Head and Face Pain 2025-01-13

Abstract. There was a significant difference in near-surface PM2.5 changes across China after the implementation of Clean Air Action Plan 2013. This study used regional climate-chemistry-ecosystem coupled model, RegCM-Chem-YIBs, to investigate interannual variations East Asia from 2008 2018. The drivers variability were examined Anthropogenic and Natural perspectives. Compared 2008, showed little variation during 2009–2013 (the PreG phase). However, 2014–2018 PostG phase), substantial...

10.5194/egusphere-2025-10 preprint EN cc-by 2025-04-14

Tension-type headache (TTH) is the most common nervous system disorder worldwide. This study aimed to examine abnormal network-level brain functional connectivity (FC) alterations in patients with TTH across multi-frequency bands. The enrolled 63 subjects, comprising 32 and 31 healthy controls (HC). According our team's previous research, regions ReHo conventional frequency band (0.01-0.08 Hz) slow-5 (0.01-0.027 were chosen as seed of interest (ROIs). Subsequently, FC between ROIs entire...

10.1186/s12880-025-01599-z article EN cc-by-nc-nd BMC Medical Imaging 2025-05-01
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