Rongrong Fan

ORCID: 0009-0007-7449-2406
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About
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Research Areas
  • Family Support in Illness
  • Air Quality Monitoring and Forecasting
  • Air Quality and Health Impacts
  • Energy and Environment Impacts
  • Per- and polyfluoroalkyl substances research
  • Cervical Cancer and HPV Research
  • Animal Disease Management and Epidemiology
  • Cancer survivorship and care
  • CRISPR and Genetic Engineering
  • Hepatitis B Virus Studies
  • Adipose Tissue and Metabolism
  • Vector-Borne Animal Diseases
  • Health and Wellbeing Research
  • Virus-based gene therapy research
  • Vaccine Coverage and Hesitancy
  • Peroxisome Proliferator-Activated Receptors
  • Viral Infections and Immunology Research
  • Viral Infectious Diseases and Gene Expression in Insects
  • Family and Patient Care in Intensive Care Units

Sichuan University
2025

Minzu University of China
2024

Qingdao University
2021-2023

Families of breast cancer patients may face discrimination and societal rejection due to prevailing myths, misconceptions causal beliefs related cancer. This study aims develop validate a measurement tool that is sensitive the affiliate stigma experienced by caregivers women with The scale was developed in two phases: (1) item generation based on interviews amongst 18 cancer; (2) psychometric properties scale, including content validity, structural internal consistency reliability. Data were...

10.1016/j.apjon.2024.100652 article EN cc-by-nc-nd Asia-Pacific Journal of Oncology Nursing 2025-01-01

Fine particulate matter (PM2.5) exposure causes DNA mutations and abnormal gene expression leading to lung cancer, but the detailed mechanisms remain unknown. Here, analysis of genomic transcriptomic changes upon a PM2.5 exposure-induced human bronchial epithelial cell-based malignant transformed cell model in vitro showed that led APOBEC mutational signatures transcriptional activation APOBEC3B along with other potential oncogenes. Moreover, by analyzing profiles 1117 non-small cancers...

10.1021/acs.est.2c08092 article EN Environmental Science & Technology 2023-04-18

Human papilloma virus (HPV) is the most common reproductive tract virus. Most HPV infections occur during adolescence or young adulthood, and thus college students are one of main target populations vaccination. However, data on knowledge vaccine as well intention to be vaccinated among Chinese were limited. The purpose this study was address gap by investigating a sample from four universities analyzing factors influencing their intention. College (N = 343) filled in survey comprised...

10.1080/21645515.2021.2007014 article EN Human Vaccines & Immunotherapeutics 2021-12-17

CD2v, a critical outer envelope glycoprotein of the African swine fever virus (ASFV), plays central role in hemadsorption phenomenon during ASFV infection and is recognized as an essential immunoprotective protein. Monoclonal antibodies (mAbs) targeting CD2v have demonstrated promise both diagnosing combating (ASF). The objective this study was to develop specific monoclonal against CD2v. In investigation, Recombinant expressed eukaryotic cells, murine mAbs were generated through meticulous...

10.3389/fimmu.2024.1352404 article EN cc-by Frontiers in Immunology 2024-05-23

6:2 Chlorinated polyfluorinated ether sulfonate (6:2 Cl-PFESA), an alternative product of perfluorooctane (PFOS), has been frequently detected in various environmental, wildlife, and human samples. A few studies revealed the hepatotoxicity Cl-PFESA animals, but underlying toxicity mechanisms remain largely unknown. In this study, we investigated lipid metabolism disorders through miRNA-gene interaction mode Huh-7 cells. Our results showed that significantly promoted cellular accumulation...

10.1016/j.ecoenv.2021.113011 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2021-11-24

ABSTRACT CRISPR/Cas9 mediated precise gene editing requires homology-directed repair (HDR), which occurs less frequently than non-homologous end-joining (NHEJ) including the canonical NHEJ and alternative (Alt-EJ) in mammalian cells, especially CHO cells that inherent resist HDR. To solve above hurdle, here we for first time show knockout DNA polymerase θ (POLθ), is essential Alt-EJ, significantly increases knock-in efficiency by nearly forty-fold via eGFP reporter system does not affect...

10.1101/2022.12.09.519421 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2022-12-10
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