A5101221865- Neuroscience and Neural Engineering
- Immune Cell Function and Interaction
- Tissue Engineering and Regenerative Medicine
- Cancer Research and Treatments
- Renal Transplantation Outcomes and Treatments
- Virus-based gene therapy research
- Digestive system and related health
- Pluripotent Stem Cells Research
- Advanced Sensor and Energy Harvesting Materials
- CAR-T cell therapy research
- Polyamine Metabolism and Applications
- Mesenchymal stem cell research
- MicroRNA in disease regulation
- Renal Diseases and Glomerulopathies
- Cancer-related molecular mechanisms research
Soochow University
2023-2025
Sichuan University
2025
West China Hospital of Sichuan University
2025
Peking University First Hospital
2024
Zero to Three
2024
Peking University
2024
King University
2024
Jiangsu Province Hospital
2008
Nanjing Medical University
2008
Abstract Bioelectricity plays a pivotal role in human physiology and pathology, particularly within the cardiovascular system. Myocardial ischemia disrupts normal transmission of electrical signals through heart, leading to cardiomyocyte death, ventricular remodeling, ultimately heart failure. Electrical stimulation (ES) has been proven be an effective strategy for treating cardiac diseases. However, invasive electrode implantation unique anatomical position limit clinical application ES...
Key Points Dysregulated IgA production plays a key role in the pathogenesis of nephropathy. Increased 5-methylcytosine modification, an epigenetic regulatory mechanism, exaggerated nephropathy phenotype mice. Conversely, inhibition modification ameliorated progression nephropathy–like kidney disease Background is important global cause failure. Dysregulation believed to play pathogenesis; however, little known about mechanisms, such as RNA (5mC) regulating synthesis. Methods To decipher 5mC...
Key Points We generated a transgenic mouse model expressing the human IgA1 heavy chain, which has hinge region with rich O -linked glycosylation. After inflammatory stimulation, showed elevated galactose-deficient levels in serum. Coupled complement H factor mutant, mice exhibited glomerular lesions, associated hematuria and albuminuria like IgA nephropathy. Background nephropathy is most common primary glomerulonephritis worldwide, there emerging evidence linking (Gd-IgA1) to pathogenesis...
Summary. We have previously showed that endothelial progenitor cells (EPCs) through uptake of hepatitis B virus (HBV) may play a critical role in mediating extrahepatic HBV diseases. However, it remains to be elucidated whether mesenchymal stem (MSCs) are capable trans‐infection into tissues. Methods and Results: In this study, we antigens, DNA the viral particles were detected MSCs after 3 days challenge. Neither covalently closed circular nor pregenomic RNA MSCs. Intravenously...