Li‐Yang Sun

ORCID: 0009-0007-8143-0836
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About
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Research Areas
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Liver Disease Diagnosis and Treatment
  • Cancer, Lipids, and Metabolism
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Hepatitis C virus research
  • Pancreatic and Hepatic Oncology Research
  • Hepatitis B Virus Studies
  • Liver Disease and Transplantation
  • Gastric Cancer Management and Outcomes
  • Inflammatory Biomarkers in Disease Prognosis
  • Cancer, Hypoxia, and Metabolism
  • Nutrition and Health in Aging
  • Esophageal and GI Pathology
  • Lung Cancer Treatments and Mutations
  • Gallbladder and Bile Duct Disorders
  • Genetics, Aging, and Longevity in Model Organisms
  • Nanoplatforms for cancer theranostics
  • Ferroptosis and cancer prognosis
  • Frailty in Older Adults
  • Lung Cancer Research Studies
  • Surgical site infection prevention
  • Supramolecular Self-Assembly in Materials
  • Antioxidants, Aging, Portulaca oleracea
  • Liver Diseases and Immunity
  • Enhanced Recovery After Surgery

Shanghai Jiao Tong University
2025

Zhejiang Provincial People's Hospital
2020-2024

Second Military Medical University
2017-2024

Hangzhou Medical College
2020-2024

Sun Yat-sen University Cancer Center
2023-2024

Affiliated Hospital of Qingdao University
2024

Qingdao University
2024

Bengbu Medical College
2022-2024

Sun Yat-sen University
2023-2024

Eastern Hepatobiliary Surgery Hospital
2017-2024

Recognizing the combustion mode in scramjet engines is critical for suppressing oscillations and stabilizing process hypersonic aircrafts. Current accesses mainly depend on mechanical measurement dominant frequencies based image analysis methods, such as proper orthogonal decomposition dynamic decomposition. However, these traditional methods either lack of precision or fall short need prior knowledge, poor generalization, low efficiency, posing challenges practical implementations,...

10.1063/5.0251192 article EN Physics of Fluids 2025-02-01

Survival after liver resection of hepatocellular carcinoma (HCC) remains poor because a high incidence recurrence. We sought to investigate risk factors, patterns, and long-term prognosis among patients with early late recurrence for hepatitis B virus (HBV)-associated HCC.Data consecutive undergoing curative HBV-associated HCC were analyzed. According the time surgery, was divided into (≤2 years) (>2 years). Characteristics, patterns initial recurrence, postrecurrence survival (PRS) compared...

10.1634/theoncologist.2019-0944 article EN The Oncologist 2020-05-30

The presence of microvascular invasion (MVI) is a significant malignant pathological feature related to recurrence and survival after liver resection for hepatocellular carcinoma (HCC). This study aimed investigate the relationship between severity in grading MVI long-term oncological outcomes patients with early-stage HCC.A retrospective was conducted on prospectively maintained multicenter database who underwent curative Barcelona Clinic Liver Cancer stage 0/A HCC 2017 2020. Patients were...

10.1097/js9.0000000000000325 article EN cc-by-nc-nd International Journal of Surgery 2023-03-28

Background and Aim: Alpha-fetoprotein (AFP), a lens culinaris agglutinin-reactive fraction of AFP (AFP-L3), is protein that induced by vitamin K deficiency or antagonist-II (PIVKA-II) has been clinically used as serum biomarker for early detection diagnosis hepatocellular carcinoma (HCC). Diagnostic performance each alone, their combinations the hepatitis C virus (HCV)-associated HCC were compared. Methods: Serum AFP, AFP-L3, PIVKA-II levels evaluated in patients with HCV-associated HCC,...

10.3390/jcm11175075 article EN Journal of Clinical Medicine 2022-08-29

Abstract Background The value of serum biomarkers, particularly alpha-fetoprotein (AFP) and protein induced by vitamin K absence or antagonist-II (PIVKA-II), gains increasing attention in prognostic evaluation recurrence monitoring for patients with hepatocellular carcinoma (HCC). This study investigated the implications serological incomplete conversion (SIC) these 2 biomarkers as indicators long-term outcomes after HCC resection. Methods A multicenter observational was conducted on a...

10.1093/oncolo/oyae139 article EN cc-by-nc The Oncologist 2024-06-22

Heatstroke, a global concern exacerbated by climate change, poses significant health risks, potentially leading to multiorgan damage and fatalities. Core body temperature (CBT) is critical precise indicator of heatstroke, its continuous monitoring could serve as pivotal tool for early detection. Traditional CBT measurements, often invasive (e.g., surgical intubation, rectal or oral placement), disrupt daily activities, whereas existing wearable devices predominantly measure skin temperatures...

10.1021/acssensors.4c03470 article EN ACS Sensors 2025-01-21

In image-guided surgery (IGS) practice, combining intraoperative 2D X-ray images with preoperative 3D from computed tomography (CT) enables the rapid and accurate localization of lesions, which allows for a more minimally invasive efficient surgery, also reduces risk secondary injuries to nerves vessels. Conventional optimization-based methods CT matching are limited in speed precision due non-convex optimization spaces constrained searching range. Recently, deep learning (DL) approaches...

10.3390/bioengineering12020114 article EN cc-by Bioengineering 2025-01-26

Aberrant lipid metabolism is an essential feature of hepatocellular carcinoma (HCC). Fatty acid transport protein-5 (FATP5) highly expressed in the liver and involved fatty pathway. However, potential role FATP5 pathogenesis HCC remains largely unknown. Herein, we showed that was downregulated tissues even much lower vascular tumor thrombi. Low expression correlated with multiple aggressive invasive clinicopathological characteristics contributed to metastasis a poor prognosis patients....

10.1038/s41389-021-00364-5 article EN cc-by Oncogenesis 2021-11-12

The GALAD and ASAP scores are two well-recognized algorithms to estimate the risk of hepatocellular carcinoma (HCC) based on gender, age, alpha-fetoprotein (AFP), protein induced by vitamin K absence or Antagonist-II (PIVKA-II) AFP-L3 (included in score but not score). current study sought compare diagnostic performance each detect HCC among patients infected with hepatitis C virus (HCV).A multicenter case-control was undertaken which blood samples were collected from HCVinfected without...

10.3389/fonc.2022.1018396 article EN cc-by Frontiers in Oncology 2022-09-30

The ASAP and GALAD scores are widely used diagnostic models for detecting hepatocellular carcinoma (HCC), incorporating factors such as sex, age, alpha-fetoprotein (AFP), protein induced by vitamin K absence or antagonist-II (PIVKA-II), lens culinaris agglutinin-reactive fraction of AFP (AFP-L3%). This study compares the efficacy in early detection HCC patients with non-alcoholic fatty liver disease (NAFLD). NAFLD without were recruited from 12 Chinese tertiary hospitals. Serum levels AFP,...

10.1016/j.iliver.2024.100098 article EN cc-by-nc-nd iLiver 2024-05-21

Nanozyme has been experiencing rapid development in biomedical applications involving biosensors, immunoassays, and antitumor agents recent years due to its tunable catalytic performance desirable biocompatibility. Since the first exploration of nanozyme‐based Fenton reaction for nanocatalytic therapy (NCT) against tumor, a variety (and Fenton‐like) nanozymes, such as Fe 3 O 4 , transition metal ions (Co 2+ Cu Mn ), metal–organic frameworks (MOFs), have proved candidates tumor therapy,...

10.1002/smsc.202200024 article EN Small Science 2022-06-03
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