A5089601564- Cervical and Thoracic Myelopathy
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Biosimilars and Bioanalytical Methods
- Pharmaceutical studies and practices
- Neuroblastoma Research and Treatments
- Medical Imaging and Analysis
- Cancer, Hypoxia, and Metabolism
- Pharmacological Effects and Toxicity Studies
- Pharmacogenetics and Drug Metabolism
Sunshine Hospital
2025
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
2018-2024
Dalian Medical University
2018-2019
Chongqing Medical University
2018-2019
Second Affiliated Hospital of Chongqing Medical University
2018-2019
22011 is an insulin degludec/insulin aspart co-formulation (IDegAsp) that shares identical amino acid sequence with Ryzodeg, the originator IDegAsp. This study aimed to compare pharmacokinetics (PK), pharmacodynamics (PD), and safety of 22,011 Ryzodeg. In a single-center, randomized, open-label, two-treatment, two-period, two-sequence, crossover, euglycemic clamp study, healthy Chinese adults were randomized receive 0.5 U/kg Ryzodeg under fasting conditions. PK was evaluated for up 120 hours...
Abstract This study aimed to evaluate the pharmacokinetics (PKs), safety, and immunogenicity of biosimilar HEC14028 compared reference Trulicity® (dulaglutide) in healthy male Chinese subjects. was a single‐center, randomized, open, single‐dose, parallel‐controlled comparative Phase I clinical trial, including screening period up 14 days, 17‐day observation after administration, 7‐day safety follow‐up period. A total 68 subjects were randomly assigned (1:1) test group (HEC14028) (single 0.75...
<title>Abstract</title> <bold>Objective:</bold> To examine the mid-term efficacy and imaging results of using Mobi-C Bryan after cervical hybrid surgery on 2-level spondylolisthesis. observe their postoperative changes differences in flexion-extension center rotation (FE-COR) anterior disc replacement (ACDR) segment. <bold>Methods</bold>: Patients who underwent between June 2014 2019 were included. The mJOA, NDI, VAS scores used to assess clinical outcomes FE-COR ACDR segment was measured....