R Yao

ORCID: 0009-0007-8759-7039
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About
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Research Areas
  • Estrogen and related hormone effects
  • Gut microbiota and health
  • Advanced Proteomics Techniques and Applications
  • Metabolomics and Mass Spectrometry Studies
  • Metallurgy and Material Forming
  • Immune Response and Inflammation
  • Cancer-related Molecular Pathways
  • Powder Metallurgy Techniques and Materials
  • Eicosanoids and Hypertension Pharmacology
  • Inflammatory mediators and NSAID effects
  • Protease and Inhibitor Mechanisms
  • Cancer Research and Treatments
  • S100 Proteins and Annexins
  • Hemoglobinopathies and Related Disorders
  • Bladder and Urothelial Cancer Treatments
  • Cancer, Lipids, and Metabolism
  • Retinoids in leukemia and cellular processes
  • Blood groups and transfusion
  • Metal Alloys Wear and Properties
  • Epigenetics and DNA Methylation
  • Pancreatic and Hepatic Oncology Research
  • Erythrocyte Function and Pathophysiology
  • Mass Spectrometry Techniques and Applications
  • Renal and related cancers
  • PI3K/AKT/mTOR signaling in cancer

Xiangya Hospital Central South University
2025

Central South University
2025

Second Military Medical University
2024

University of Shanghai for Science and Technology
2024

Washington University in St. Louis
2005-2009

University of Alabama at Birmingham
2008

National Cancer Institute
2008

Alvin J. Siteman Cancer Center
2007

Beijing Institute of Aeronautical Materials
2005

The Ohio State University
2001

Abstract Hemolytic anemia (HA) is characterized by massive destruction of red blood cells (RBCs) and insufficient oxygen supply, which can lead to shock, organ failure, even death. Recent studies have preliminarily demonstrated the therapeutic effectiveness whole exchange (WBE) in management acute hemolytic exhibited potential for reducing duration corticosteroid treatment, while underlying mechanism WBE therapy was not investigated preclinical study. Hence, we investigate mechanisms HA...

10.1096/fj.202401748rr article EN cc-by-nc The FASEB Journal 2025-01-29

AbstractRecent studies suggested that nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit lung tumorigenesis under conditions are immunosuppressive. We hypothesized this inhibition of mouse requires induction apoptosis and COX(cyclooxygenase)-1, COX-2, the incidence K-ras mutation. The NSAIDs used in study include acetylsalicylic acid (ASA) is with COX-1and COX-2inhibition N-[2-(cyclohexyloxy)4-nitrophenyl]-methanesulfonamide (NS398) a specific COX-2inhibitor. Wehave previously...

10.1080/01902140150216783 article EN Experimental Lung Research 2000-01-01

Purpose: Bladder cancer (BC) is one of the top 10 common tumors in world.It has been reported that microbiota can colonize tissues and play important roles tumorigenesis progression.However, current understanding microorganisms BC tissue microenvironment remains unclear.Methods: In this study, we integrated RNA-seq data 479 samples from seven datasets combined with a range bioinformatics tools to explore landscape microbiome microenvironment.Results: The pan-microbiome was estimated surpass...

10.7150/jca.93055 article EN cc-by-nc Journal of Cancer 2024-01-01

Microbiota is present in the human tissue microenvironment and closely related to tumorigenesis treatment. However, landscape of microbiome its relationship with tumors remain less understood. In this study, we re-analyzed omics data from 7104 samples (94 projects for 15 cancers) NCBI database obtain microbial profiles. After normalization decontamination processing, established classification models distinguish between different tumor adjacent normal tissues. The had excellent performances,...

10.1093/bib/bbaf057 article EN cc-by Briefings in Bioinformatics 2024-11-22

IN718 has been developed in China for applications as aero-engine disks, seals and rings during the last twenty years.Although wrought products of could meet requirements aeroengine components, they exhibited chemical segregation large grain structure were difficult-to-process.To overcome problems encountered with alloy, a research program aims to develop unique spray forming process make sound ring performs rolled parts.Trials conducted optimize parameters producing high quality rings.This...

10.7449/2005/superalloys_2005_321_328 article EN 2005-01-01

Abstract #1109 In the MNU induced model of mammary cancer, rats given a single dose (75 mg/kg BW), via jugular vein, at 50 days age develop multiple ER+ cancers. These cancers appear similar to highly differentiated human breast cancers, and have been shown be sensitive many same chemotherapeutic agents that are effective in women. When female rat developed its first palpable it was placed metabolic cage urine collected overnight on dry ice. The from these were compared those obtained...

10.1158/0008-5472.sabcs-1109 article EN Cancer Research 2009-01-01
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