Li Chen

ORCID: 0009-0007-9049-2561
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Research Areas
  • Inflammatory Bowel Disease
  • Cancer Immunotherapy and Biomarkers
  • CAR-T cell therapy research
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Neurological Disease Mechanisms and Treatments
  • Sphingolipid Metabolism and Signaling
  • Dementia and Cognitive Impairment Research
  • Liver Disease Diagnosis and Treatment
  • Childhood Cancer Survivors' Quality of Life
  • Colorectal Cancer Treatments and Studies
  • Pneumonia and Respiratory Infections
  • Liver physiology and pathology
  • Acute Ischemic Stroke Management

Second Affiliated Hospital of Nanjing Medical University
2025

North Sichuan Medical University
2024

Johnson University
2024

New York University
2020

<title>Abstract</title> <bold>Background:</bold> To investigate the effectiveness of routine nutritional screening for malnutrition risk in hospitalized children with acute lymphoblastic leukemia (ALL) on maintenance chemotherapy from viewpoint clinical outcomes. <bold>Methods:</bold> The reviews 1038 pediatric patients were retrieved retrospective, propensity score-matched, superiority study. A 1:1 score matching was utilized to match who received (screening cohort) those remained usual...

10.21203/rs.3.rs-6248851/v1 preprint EN Research Square (Research Square) 2025-04-21

Abstract Objective Abnormalities in the gray matter structure of cerebral small vessel disease (CSVD) have been observed throughout brain. However, whether cortico‐cortical connections exist between regions atrophy patients with CSVD has not fully elucidated. This question was tested by comparing covariance networks and without cognitive impairment (CI). Methods We performed multivariate modeling volume measurements 61 CI (CSVD‐CI), 85 (CSVD‐NC), 108 healthy controls using source‐based...

10.1002/acn3.52030 article EN cc-by-nc-nd Annals of Clinical and Translational Neurology 2024-03-03

Abstract Background Previous retrospective studies have demonstrated that patients with inflammatory bowel disease (IBD) exposed to anti-TNF and/or immunomodulators (IMM) following a diagnosis of cancer were not at an increased risk new or recurrent compared those unexposed these agents. Prospective are lacking and little is known about ustekinumab vedolizumab. The SAPPHIRE Registry was developed prospectively examine whether IBD history subsequently immunosuppressive therapies greater...

10.1093/ecco-jcc/jjz203.857 article EN Journal of Crohn s and Colitis 2020-01-01

Abstract Background For patients with inflammatory bowel disease (IBD) and a history of cancer, retrospective studies have failed to find evidence suggesting that exposure biologic and/or immunomodulator (IMM) agents was associated new or recurrent cancer. The SAPPHIRE Registry developed prospectively examine this issue. Methods Patients IBD who had confirmed first (index) cancer 5 years prior enrollment were recruited from centers affiliated the New York Crohn’s Colitis Organization (NYCCO)...

10.1093/ecco-jcc/jjad212.0834 article EN Journal of Crohn s and Colitis 2024-01-01
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