A5051524762- RNA Research and Splicing
- RNA modifications and cancer
- RNA and protein synthesis mechanisms
- Immune Cell Function and Interaction
- Reproductive System and Pregnancy
- T-cell and B-cell Immunology
- CRISPR and Genetic Engineering
- Single-cell and spatial transcriptomics
- Cancer-related gene regulation
- Endometriosis Research and Treatment
- Autophagy in Disease and Therapy
- Advanced biosensing and bioanalysis techniques
- Plant Virus Research Studies
Tsinghua University
2024
Shanghai Institutes for Biological Sciences
2016-2018
Shanghai Jiao Tong University
2016-2018
Chinese Academy of Sciences
2016-2018
Shanghai Institute of Nutrition and Health
2018
University of Chinese Academy of Sciences
2017
Pregnancy loss occurs in about 15% of clinically recognized pregnancies, and defective maternal-fetal immune tolerance contributes to more than 50% these events. We found that signaling by the type I membrane protein T cell immunoglobulin mucin-containing 3 (Tim-3) natural killer (NK) cells had an essential protective role during early pregnancy. Tim-3 on peripheral NK (pNK) was transiently increased abundance first trimester pregnancy, which depended interleukin-4 (IL-4)-signal transducer...
Abstract With large amounts of unlabeled RNA sequences data produced by high-throughput sequencing technologies, pre-trained language models have been developed to estimate semantic space molecules, which facilities the understanding grammar language. However, existing overlook impact structure when modeling space, resulting in incomplete feature extraction and suboptimal performance across various downstream tasks. In this study, we a model named ERNIE-RNA ( E nhanced R eprese n tations...
Objective To investigate the expression of autophagy related gene Beclin-1 and Drosophila Zeste homolog 2 enhancer in tissue clear cell renal carcinoma prediction value carcinoma. Methods 32 patients with were selected.The fresh specimens adjacent tissues collected respectively.In addition, paraffin specimen 136 underwent radical nephrectomy collected.The EZH2 Beclin 1 above detected respectively by methods protein immunoblot real-time fluorescence quantitative PCR immunohistochemical...