- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Family and Patient Care in Intensive Care Units
- Tracheal and airway disorders
- Cardiac Arrest and Resuscitation
- Airway Management and Intubation Techniques
- Mechanical Circulatory Support Devices
- Anesthesia and Sedative Agents
- Inhalation and Respiratory Drug Delivery
- Non-Invasive Vital Sign Monitoring
- Nosocomial Infections in ICU
- Hemodynamic Monitoring and Therapy
- Anesthesia and Neurotoxicity Research
- Neonatal Respiratory Health Research
- Renal function and acid-base balance
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiac, Anesthesia and Surgical Outcomes
- Liver Disease Diagnosis and Treatment
- Heart Failure Treatment and Management
Hospital Clínico San Carlos
2024
Hospital Universitario Infanta Sofía
2012-2016
Hospital General Universitario de Ciudad Real
2015
Hospital Universitario Fundación Jiménez Díaz
2008-2009
Centro de Investigación Biomédica en Red
2009
Hospital Universitario 12 De Octubre
2002
Associação de Medicina Intensiva Brasileira
2002
High-flow conditioned oxygen therapy delivered through nasal cannulae and noninvasive mechanical ventilation (NIV) may reduce the need for reintubation. Among advantages of high-flow are comfort, availability, lower costs, additional physiopathological mechanisms.To test if is noninferior to NIV preventing postextubation respiratory failure reintubation in patients at high risk reintubation.Multicenter randomized clinical trial 3 intensive care units Spain (September 2012-October 2014)...
Studies of mechanically ventilated critically ill patients that combine populations are at high and low risk for reintubation suggest conditioned high-flow nasal cannula oxygen therapy after extubation improves oxygenation compared with conventional therapy. However, conclusive data about lacking.To determine whether is superior to preventing in reintubation.Multicenter randomized clinical trial conducted between September 2012 October 2014 7 intensive care units (ICUs) Spain. Participants...
<h3>BACKGROUND:</h3> Open respiratory secretion suctioning with a catheter causes pain and tracheobronchial mucosal injury in intubated patients. The goal of mechanical insufflation-exsufflation (MI-E) is to move secretions proximally noninvasively by generating high peak expiratory air flow. Nebulized hypertonic saline hyaluronic acid (HS-HA) may facilitate hydration. We assessed the safety tolerance single session airway clearance MI-E HS-HA critically ill <h3>METHODS:</h3> Adults cuffed...
Critically ill mechanically ventilated patients are usually stratified in two levels according to the risk for reintubation. In low-risk high flow conditioned oxygen therapy (HFO) may reduce reintubation, whereas high-risk non-invasive mechanical ventilation (NIMV) prevent reintubation is gaining acceptance. However, data on efficacy or safety of HFO lacking.
Results Mean CVP (8,23 +/3,12 mmHg) was normal, whereas mean GEDI (615,2 +/135,44 mL/m2) decreased. Thirty-one measurements were elevated despite simultaneous levels indicating a normal or decreased preload. Sensitivity, specificity, positive predictive value, and negative value of with regard to volume depletion (GEDI < 650) 6,28 (0-12,77. CI 95%), 100 (97,86-100, 95%, 43, 2 (28,99-50,82, 95%) respectively. did not correlate (r = -0,065, p 0,32), 0,23, 0,176) EVLWI (extravascular lung water...