Clint McDaniel

ORCID: 0009-0008-0159-6076
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About
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Research Areas
  • Respiratory viral infections research
  • Influenza Virus Research Studies
  • Escherichia coli research studies

Sanofi (United States)
2024

Abstract Neuraminidase (NA), the second most abundant surface glycoprotein on influenza virus, plays a key role in viral replication and propagation. Despite growing evidence showing that NA-specific antibodies correlate with resistance to disease humans, current licensed vaccines focus almost entirely hemagglutinin (HA) antigen. Here, we demonstrate recombinant NA (rNA) protein is highly immunogenic both naïve mice ferrets, as well pre-immune irrespective of level match preexisting...

10.1038/s41541-024-01011-x article EN cc-by npj Vaccines 2024-11-19
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