Isabella Di Filippo

ORCID: 0009-0008-0523-7441
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Impact on Reproduction
  • Pregnancy and Medication Impact
  • Long-Term Effects of COVID-19
  • Reproductive System and Pregnancy
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Antifungal resistance and susceptibility
  • Antibiotics Pharmacokinetics and Efficacy
  • Urinary Tract Infections Management
  • Antibiotic Resistance in Bacteria
  • HIV/AIDS oral health manifestations
  • Drug-Induced Adverse Reactions
  • Tryptophan and brain disorders
  • HIV Research and Treatment
  • Alzheimer's disease research and treatments
  • Diabetes Management and Research
  • Diabetes and associated disorders
  • Pregnancy and preeclampsia studies
  • SARS-CoV-2 detection and testing

University of Naples Federico II
2022-2024

Federico II University Hospital
2022-2023

Urinary tract infections (UTIs) are the second most frequent type of infection observed in clinical practice. Gram-negative Enterobacteriaceae common pathogens UTIs. Excessive antibiotic use humans and animals, poor control, increased global travel have accelerated spread multidrug-resistant strains (MDR). Carbapenem antibiotics commonly considered last line defense against MDR bacteria; however, their efficacy is now threatened by increasing prevalence carbapenem-resistant (CRE). This...

10.3390/medicina60020214 article EN cc-by Medicina 2024-01-26

Pneumocystis jirovecii pneumonia (PJP) is an invasive fungal infection (IFI) that occurs mainly in immunocompromised hosts. After observing a high prevalence of PJP as complication COVID-19 immunocompetent patients, we conducted study to evaluate the P. colonization with PCR on oral washing samples (OWS) among non-immunocompromised and non-critical patients admitted at our university hospital.All over 18 years age Infectious Diseases Unit for SARS-CoV-2 between July 2021 December 2022 were...

10.3390/microorganisms11122839 article EN cc-by Microorganisms 2023-11-22

More than 2 years after the pandemic, availability of vaccination and use monoclonal antibodies direct antivirals have changed fate COVID-19, allowing for a better management disease, reducing hospitalization rates, improving survival. This study aims to describe outcome COVID-19 in cohort solid organ transplant recipients impact novel against SARS-CoV-2. We conducted an observational retrospective study. enrolled with attending A.O.U. Federico II Naples followed up from January 2022 July...

10.3389/frtra.2023.1095225 article EN cc-by Frontiers in Transplantation 2023-03-16

BACKGROUND
 Pneumocystis jirovecii pneumonia (PJP) is an invasive fungal infection (IFI) that occurs mainly in immunocompromised hosts. As we observed a high prevalence of PCP as complication COVID-19 immunocompetent patients, conducted study to evaluate the P. colonization with PCR on oral washing samples (OWS) among non-immunocompromised and non-critical patients admitted for at our University Hospital.
 METHODS
 All over 18 years age Infectious Diseases Unit SARS-CoV-2...

10.20944/preprints202308.2206.v1 preprint EN 2023-08-31

Despite the lightning-fast advances in management of SARS-CoV after 2 years pandemic, COVID-19 continues to pose a challenge for fragile patients, who could benefit from early administration monoclonal antibodies (mAbs) reduce risk severe disease progression. We conducted prospective study evaluate effectiveness mAbs against SARS-CoV-2 among patients at progression, namely elderly and those with comorbidities, before omicron variant surge. Patients were treated either casirivimab/imdevimab,...

10.3390/vaccines10111895 article EN cc-by Vaccines 2022-11-10

Diabetes mellitus represents one of the most frequent comorbidities among patients with COVID-19, constituting a risk factor for more severe prognosis than that non-diabetic patients. However, pathophysiological mechanism underlying this unfavorable outcome is still not completely clear. The goal our study was to evaluate potential role antidiabetic therapy in evolution COVID-19.

10.3390/microorganisms11010145 article EN cc-by Microorganisms 2023-01-06

The aim of this study was to report the use casirivimab/imdevimab therapy in pregnant women with moderate coronavirus disease 2019 (COVID-19).

10.1055/s-0042-1753488 article EN American Journal of Perinatology 2023-04-18

Abstract Despite the lightning-fast advances in management of SARS-CoV after 2 years pandemic, COVID-19 continues to pose a challenge for fragile patients, who could benefit from early administration monoclonal antibodies (mAbs) reduce risk severe disease progression. We conducted prospective study evaluate effectiveness mAbs against SARS-CoV-2 among patients at progression, namely elderly and those with comorbidities, before omicron variant surge. Patients were treated either...

10.20944/preprints202209.0297.v1 preprint EN 2022-09-20

Abstract Objective Our objective was to evaluate the safety and efficacy of casirivimab/imdevimab therapy in pregnant women with severe coronavirus disease 2019 (COVID-19) requiring oxygen therapy. Study Design This a prospective case series study aimed unvaccinated COVID-19. Inclusion criteria were acute respiratory syndrome 2 infection documented polymerase chain reaction, pregnancy, COVID-19 therapy, duration symptoms 10 days or less, able provide informed consent. Vaccinated those...

10.1055/a-1925-2017 article EN American Journal of Perinatology 2022-08-16
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