A5060525222- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- Immunotherapy and Immune Responses
- Adolescent Sexual and Reproductive Health
- HIV-related health complications and treatments
- Prenatal Screening and Diagnostics
- Adolescent and Pediatric Healthcare
- Toxoplasma gondii Research Studies
- Syphilis Diagnosis and Treatment
- Immune Cell Function and Interaction
- Eosinophilic Esophagitis
- Inflammatory Bowel Disease
- Immunodeficiency and Autoimmune Disorders
- HIV/AIDS drug development and treatment
- Pediatric health and respiratory diseases
- Cytomegalovirus and herpesvirus research
- Breastfeeding Practices and Influences
University of Miami
2005-2024
Background Until recently, breastfeeding has been contraindicated for women living with HIV (WHIV) in the U.S. However, given numerous health benefits of breastfeeding, recommendations have changed to support parental choice breastfeed through shared decision-making. Although specific guidelines managing care these and their infants are not yet available, various approaches successful without acquiring from virologically suppressed mothers, thus, establishing as a viable option rising number...
Background: Defects of plasmacytoid (p) and myeloid (m) dendritic cells (DCs) occur in HIV infection. The aim this study was to evaluate the maturation function DCs children with perinatal infection who were on antiretroviral therapy. Materials Methods: Twenty HIV-infected (median age = 12.9 years) classified as immunologic/virologic responders failures evaluated a whole-blood assay resiquimod (RSQ), potent agonist Toll-like receptors 7 8, DC stimulant. Results: In comparison controls, pDC...
Inflammatory bowel disease is infrequently reported among HIV-infected adults and rarely in children. The course of IBD may be less severe patients because underlying immunosuppression from the virus.One perinatally adolescent one young adult were diagnosed with Crohn's at University Miami Pediatric Gastroenterology Program. A retrospective review medical records including history, physical examination, laboratory, radiographic pathology results was performed.Case 1: 20 year-old African...
Materials and methods Patients with perinatal HIV infection (n = 19, ages 11–18 yr, on HAART) were classified as immunologic responders (IR+; CD4>25%), virologic (VR; plasma RNA < 400 copies/mL). mDC (Lin-, HLA DR+CD11c+) pDC DR+ CD11c-) evaluated in a novel whole blood assay by flow cytometry for expression of maturation markers CD83, CD80, homing receptor CCR7 intracellular cytokines (TNF-α IFN-α) after short-term stimulation TLR7/8 agonist, resiquimod.
Abstract Background This study is analysis the consequences of reverse syphilis screening on management newborns exposed to maternal syphilis, and pediatric physicians’ adherence existing guidelines. Methods We conducted a 5-year retrospective review population their diagnosed with syphilis. Women positive results (TT+/NTT+) discordant (TT+/NTT-/TT+) were included in analysis. Results Per American Academy Pediatrics (AAP), 202 divided two groups: proved or highly probable possible congenital...