- Plant Toxicity and Pharmacological Properties
- Drug-Induced Hepatotoxicity and Protection
- Poisoning and overdose treatments
- Cancer Mechanisms and Therapy
- Hippo pathway signaling and YAP/TAZ
- S100 Proteins and Annexins
- Thyroid Cancer Diagnosis and Treatment
- Ferroelectric and Piezoelectric Materials
- Acoustic Wave Resonator Technologies
- Microwave Dielectric Ceramics Synthesis
- Hepatitis B Virus Studies
- Brain Metastases and Treatment
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Cancer-related molecular mechanisms research
- Cancer-related Molecular Pathways
- RNA Research and Splicing
Xuzhou Medical College
2024
Affiliated Hospital of North Sichuan Medical College
2023
Yantai University
2022
North Sichuan Medical University
2019-2021
Union Hospital
2016-2020
Huazhong University of Science and Technology
2016-2020
Abstract Hepatic sinusoidal obstruction syndrome (HSOS) can be caused by pyrrolizidine alkaloids(PAs)-containing herbals. Since PAs exposure is obscure and clinical presentation of HSOS unspecific, it challenge to establish the diagnosis PAs-induced HSOS. Gynura segetum one most wide-use herbals containing PAs. The aim our study describe features contrast-enhanced computed tomography (CT) in gynura segetum-induced HSOS, then determine diagnostic performance radiological signs. We...
One major etiology of hepatic sinusoidal obstruction syndrome (HSOS) in China is the intake pyrrolizidine alkaloids (PAs). Since PAs-induced HSOS a rare disease that has not been clearly characterized until now, aim this study was to investigate clinical characteristics, CT features, and pathological findings PA-induced HSOS.This retrospective cohort included 116 patients with 68 Budd-Chiari from Jan 2006 Sep 2016. We collected medical records patients, reviewed image features CT, analyzed...
ABSTRACT Clinical studies of tenofovir amibufenamide (TMF) and alafenamide (TAF) treatment in patients with HBV‐related decompensated cirrhosis (HBV‐DC) are limited. This study evaluated the efficacy safety TMF versus TAF naive‐treated first‐time HBV‐DC. Based on antiviral drug used, were categorised into group group. Virological serological responses, hepatic renal functions blood lipid changes both groups during 48 weeks treatment. A total 98 enrolled, 45 53 At treatment, proportions who...
Breast cancer is the most common worldwide. Low DNAJB4 expression levels are strongly correlated with poor prognosis in breast patients. However, molecular mechanism by which regulates progression unclear.The of was validated human tissues, normal and cell lines. CCK-8, colony-forming, wound healing assays were used to assess biological effect overexpression on proliferation migration MCF-7 Bioinformatic analysis identify related pathways cancer. Epithelial-mesenchymal transition...
Objective To explore the expression of Delta/Notch-like epidermal growth factor-related receptor (DNER) in triple negative breast cancer (TNBC) and analyze its correlation with clinicopathological characteristics TNBC patients. Methods The samples tissues adjacent normal were collected from 39 cases Affiliated Hospital North Sichuan Medical College March 2017 to 2018 for a retrospective study. The protein mRNA expressions DNER detected by immunohistochemistry RT-PCR, respectively....
Abstract Background Genetic mutations have been reported in many tumors. In this study, we aimed to examine whether ANXA2 occur breast cancer and investigate their association with clinicopathological characteristics patients. Materials Methods We collected adjacent normal tissue samples from 112 patients, extracted total RNA, performed PCR-SSCP bidirectional Sanger sequencing. were identified by NCBI BLAST (blastn blastx), correlation clinical data analyzed. Results detected tissues...