About
Contact & Profiles
A5065405853
Research Areas
- RNA regulation and disease
- Spaceflight effects on biology
- Endoplasmic Reticulum Stress and Disease
- Melanoma and MAPK Pathways
- Cancer Mechanisms and Therapy
- Adipose Tissue and Metabolism
- Cytokine Signaling Pathways and Interactions
- Biochemical effects in animals
- RNA Research and Splicing
University of Turin
2024
Mutations in the RAS–RAF–MEK–ERK pathway are frequent alterations cancer and RASopathies, while RAS oncogene activation alone affects 19% of all patients accounts for approximately 3.4 million new cases every year, less cascade's downstream effectors also involved etiology. proteins initiate signaling cascade by promoting dimerization RAF kinases, which can act as oncoproteins well: BRAF V600E is most common oncogenic driver, mutated 8% malignancies. Research this field led to development...
10.1002/1878-0261.13605
article
EN
cc-by
Molecular Oncology
2024-02-16
10.1016/j.jbc.2024.107859
article
EN
cc-by
Journal of Biological Chemistry
2024-10-05
Coming Soon ...