William A. Rutala

ORCID: 0009-0008-4635-8709
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About
Contact & Profiles
Research Areas
  • Medical Device Sterilization and Disinfection
  • Infection Control in Healthcare
  • Infection Control and Ventilation
  • Nosocomial Infections in ICU
  • Healthcare and Environmental Waste Management
  • Clostridium difficile and Clostridium perfringens research
  • Antibiotic Resistance in Bacteria
  • Safe Handling of Antineoplastic Drugs
  • Antimicrobial agents and applications
  • Antibiotic Use and Resistance
  • Viral gastroenteritis research and epidemiology
  • Antimicrobial Resistance in Staphylococcus
  • Listeria monocytogenes in Food Safety
  • Bacillus and Francisella bacterial research
  • Antifungal resistance and susceptibility
  • Dental Research and COVID-19
  • Vibrio bacteria research studies
  • Burn Injury Management and Outcomes
  • Vaccine Coverage and Hesitancy
  • Bacterial Identification and Susceptibility Testing
  • Bacterial biofilms and quorum sensing
  • Healthcare cost, quality, practices
  • Legionella and Acanthamoeba research
  • Mycobacterium research and diagnosis
  • Urinary Tract Infections Management

University of North Carolina at Chapel Hill
2016-2025

University of North Carolina Health Care
2013-2024

University of North Carolina Hospitals
1996-2023

Communities In Schools of Orange County
1981-2023

Oregon Medical Research Center
2022-2023

New York Proton Center
2007-2023

Manhattan Institute for Policy Research
2022-2023

University of Pittsburgh
2022-2023

Lindsay Unified School District
2022-2023

Advisory Board Company (United States)
1985-2023

Background: Although many catheter-related blood-stream infections (CRBSIs) are preventable, measures to reduce these not uniformly implemented. Objective: To update an existing evidenced-based guideline that promotes strategies prevent CRBSIs. Data Sources: The MEDLINE database, conference proceedings, and bibliographies of review articles book chapters were searched for relevant articles. Studies Included: Laboratory-based studies, controlled clinical trials, prospective interventional...

10.1086/502007 article EN Infection Control and Hospital Epidemiology 2002-12-01

ABSTRACT Assessment of the risks posed by severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) on surfaces requires data survival this virus environmental and how is affected variables, such as air temperature (AT) relative humidity (RH). The use surrogate viruses has potential to overcome challenges working with SARS-CoV increase available surfaces. Two surrogates were evaluated in study; transmissible gastroenteritis (TGEV) mouse hepatitis (MHV) used determine effects AT RH...

10.1128/aem.02291-09 article EN Applied and Environmental Microbiology 2010-03-13

10.1016/0196-6553(90)90089-b article EN American Journal of Infection Control 1990-04-01

Factors associated with lack of antibody response to the hepatitis B virus plasma vaccine were retrospectively evaluated by means a logistic regression in 194 previously seronegative staff members community hospital. All subjects had received three doses intramuscular buttock injection using 1-in, 23-gauge needle. Overall, only 55.7% developed detectable surface antigen serum after immunization. The weight-height index served as surrogate measure obesity. Predictors poor immunogenic included...

10.1001/jama.1985.03360220053027 article EN JAMA 1985-12-13

Hospital water may serve as a reservoir of healthcare-associated pathogens, and contaminated can lead to outbreaks severe infections. The clinical features waterborne infections well prevention strategies control measures are reviewed. common pathogens were bacteria, including Legionella other gram-negative nontuberculous mycobacteria, although fungi viruses occasionally described. These caused variety infections, bacteremia invasive disseminated diseases, particularly among...

10.1093/cid/ciw122 article EN Clinical Infectious Diseases 2016-03-01

Prion diseases constitute a unique infection control problem because prions exhibit unusual resistance to conventional chemical and physical decontamination methods. Recommendations prevent cross-transmission of from medical devices contaminated by Creutzfeldt-Jakob disease (CJD) have been based primarily on prion inactivation studies. The recommendations in this article consider data but also use epidemiological studies transmission, infectivity human tissues, efficacy removing microbes...

10.1086/319997 article EN Clinical Infectious Diseases 2001-05-01

Fifty interactions between healthcare workers and patients were observed to obtain a quantifiable definition of "high-touch" (ie, frequently touched) surfaces based on frequency contact. Five defined as high-touch surfaces: the bed rails, surface, supply cart, over-bed table, intravenous pump.

10.1086/655016 article EN Infection Control and Hospital Epidemiology 2010-06-22

The purpose of the study was to examine risk factors for nosocomial pneumonia in surgical and medical/respiratory intensive care unit (ICU) populations. In a public teaching hospital, all cases ICUs (n = 20, respectively) were identified by prospective surveillance during 5-yr period from 1987-1991. Each group ICU compared with 40 control patients who did not acquire pneumonia, analyzed 25 potential factors. Surgical found have consistently higher rates than medical (RR 2.2). strongest...

10.1164/ajrccm.153.1.8542110 article EN American Journal of Respiratory and Critical Care Medicine 1996-01-01

Abstract We evaluated a personal protective equipment removal protocol designed to minimize wearer contamination with pathogens. Following this often resulted in virus transfer hands and clothing. An altered or other measures are needed prevent healthcare worker contamination.

10.3201/eid1408.080085 article EN cc-by Emerging infectious diseases 2008-08-01

Nosocomial pneumonia is the leading cause of mortality attributed to nosocomial infection. Appropriate empirical therapy has been associated with improved survival, but data are limited regarding etiologic agents hospital-acquired in nonventilated patients (HAP). This evaluation assessed whether currently recommended appropriate for both ventilator-associated (VAP) and HAP by evaluating infecting flora.Prospectively collected hospitalwide surveillance was obtained infection control...

10.1086/518460 article EN Infection Control and Hospital Epidemiology 2007-06-11

Health care-associated infections most commonly result from person-to-person transmission via the hands of health care workers.We studied efficacy hand hygiene agents (n = 14) following 10-second applications to reduce level challenge organisms (Serratia marcescens and MS2 bacteriophage) healthy volunteers using ASTM-E-1174-94 test method.The highest log 10 reductions S were achieved with containing chlorhexidine gluconate (CHG), triclosan, benzethonium chloride, controls, tap water alone...

10.1016/j.ajic.2004.08.005 article EN other-oa American Journal of Infection Control 2005-02-25

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10.1086/650197 article EN Infection Control and Hospital Epidemiology 2010-01-07
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